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The map label for this gene is murB [H]

Identifier: 161869755

GI number: 161869755

Start: 779071

End: 780165

Strand: Reverse

Name: murB [H]

Synonym: NMCC_0775

Alternate gene names: 161869755

Gene position: 780165-779071 (Counterclockwise)

Preceding gene: 161869757

Following gene: 161869754

Centisome position: 36.23

GC content: 53.88

Gene sequence:

>1095_bases
TTGAATTTCCCTAGTTATCTAGGACAGCCCCAAACATATTTTAAAGTTCAAACCATGCAACCCATCCGATACCGAACCGA
CCTCACCCCCTACAACACCTTCGGTCTTCGCGCCCAAGCCCGAGCCTTTATTGCGCTTGAACACGCCGACGGGTTGCGCG
ACATCGTCCGACTGCCCGAGTTCGACCGCGATACTGTTTTATGGCTGGGCGGCGGCAGCAACATCCTTTTGATGCAGGAT
TACGCCGGACTGGTCGTACACATGGAAAACAAAGGCATACGCGAGATTGCGCGTTCAGACGGCATGGTTCTGATTGAAGC
GCAGGCGGGCGAAATTTGGCACGATTTTGTCCTGCACACCGTTGCGCTGGGTTTGAGCGGTTTGGAAAACCTGAGCCTGA
TTCCGGGTACGGTCGGCGCATCGCCCGTGCAGAACATCGGCGCATACGGCGTGGAGGCGAAAGACGTGATTCACAGCGTG
CGCTGCTTTGATTTGGATACGGAAACCTTTGTAACCCTTTCCAATGCCGACTGCCGCTTTGCCTACCGCGAAAGCCTGTT
CAAGCAGGAAGGCAAAGGGCGTTATGTGATTGTTTCGGTCGTATTTGCATTAAAAACGCATTTTGTGCCGAACTTGGGCT
ACGGAGATTTGGCGGCGAAGGTTGCCGAATTGAGTGCAGGCAGGGAGGCGACGGCGAAAGATGTTTCCGATGCAGTGTGT
GCAATCCGCAACAGTAAACTTCCTAATCCTAACGTGCTTGGCAATGTCGGCAGTTTCTTTAAAAATCCCGTCATCGGCGC
GGAAAAAGCTGCCGCCCTGTTGGAGCAGCATCCCGATATGCCGCATTATCCGCAGCCCGACGGTTCGGTCAAACTCGCCG
CCGGCTGGCTGATCGACCAATGTCGTCTGAAAGGCTTTCAAATCGGCGGCGCGGCGGTACATGGCAGGCAGGCTTTGGTC
TTAGTGAACAAAAACAACGCCTCGGCAAACGATGTCCGGCAATTGGCGCAACACATCAAATTTACAGTATTTGCTCGGTT
TCAGGTAGAATTGCACGCCGAACCCAATTGGCTGCCTGCTTCGTTCAGCCTGTAA

Upstream 100 bases:

>100_bases
GCTGTTCTTGCAGTTACACCTGCGACAAATAGCTCAATGAGTTTATTTTGTTTATACCGGCTTAGACGACTTTTTCTCAT
AAAAGCAACTCTAACTTAAT

Downstream 100 bases:

>100_bases
ATCCAAGGAGTATGCCCGTGACCCGCCCCGCCAAAATCAATACTTACACACGCATCATCGACGCCAGCCTTGCGCTCTTC
AACGAGGAAGGCGAGCGCAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MNFPSYLGQPQTYFKVQTMQPIRYRTDLTPYNTFGLRAQARAFIALEHADGLRDIVRLPEFDRDTVLWLGGGSNILLMQD
YAGLVVHMENKGIREIARSDGMVLIEAQAGEIWHDFVLHTVALGLSGLENLSLIPGTVGASPVQNIGAYGVEAKDVIHSV
RCFDLDTETFVTLSNADCRFAYRESLFKQEGKGRYVIVSVVFALKTHFVPNLGYGDLAAKVAELSAGREATAKDVSDAVC
AIRNSKLPNPNVLGNVGSFFKNPVIGAEKAAALLEQHPDMPHYPQPDGSVKLAAGWLIDQCRLKGFQIGGAAVHGRQALV
LVNKNNASANDVRQLAQHIKFTVFARFQVELHAEPNWLPASFSL

Sequences:

>Translated_364_residues
MNFPSYLGQPQTYFKVQTMQPIRYRTDLTPYNTFGLRAQARAFIALEHADGLRDIVRLPEFDRDTVLWLGGGSNILLMQD
YAGLVVHMENKGIREIARSDGMVLIEAQAGEIWHDFVLHTVALGLSGLENLSLIPGTVGASPVQNIGAYGVEAKDVIHSV
RCFDLDTETFVTLSNADCRFAYRESLFKQEGKGRYVIVSVVFALKTHFVPNLGYGDLAAKVAELSAGREATAKDVSDAVC
AIRNSKLPNPNVLGNVGSFFKNPVIGAEKAAALLEQHPDMPHYPQPDGSVKLAAGWLIDQCRLKGFQIGGAAVHGRQALV
LVNKNNASANDVRQLAQHIKFTVFARFQVELHAEPNWLPASFSL
>Mature_364_residues
MNFPSYLGQPQTYFKVQTMQPIRYRTDLTPYNTFGLRAQARAFIALEHADGLRDIVRLPEFDRDTVLWLGGGSNILLMQD
YAGLVVHMENKGIREIARSDGMVLIEAQAGEIWHDFVLHTVALGLSGLENLSLIPGTVGASPVQNIGAYGVEAKDVIHSV
RCFDLDTETFVTLSNADCRFAYRESLFKQEGKGRYVIVSVVFALKTHFVPNLGYGDLAAKVAELSAGREATAKDVSDAVC
AIRNSKLPNPNVLGNVGSFFKNPVIGAEKAAALLEQHPDMPHYPQPDGSVKLAAGWLIDQCRLKGFQIGGAAVHGRQALV
LVNKNNASANDVRQLAQHIKFTVFARFQVELHAEPNWLPASFSL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=334, Percent_Identity=48.502994011976, Blast_Score=296, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 39917; Mature: 39917

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPSYLGQPQTYFKVQTMQPIRYRTDLTPYNTFGLRAQARAFIALEHADGLRDIVRLPE
CCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCCEECEEEEEEECCCCHHHHHHCCC
FDRDTVLWLGGGSNILLMQDYAGLVVHMENKGIREIARSDGMVLIEAQAGEIWHDFVLHT
CCCCEEEEEECCCCEEEEECCCCEEEEECCCCHHHHHHCCCEEEEEECCCHHHHHHHHHH
VALGLSGLENLSLIPGTVGASPVQNIGAYGVEAKDVIHSVRCFDLDTETFVTLSNADCRF
HHHHHCCCCCCEECCCCCCCCHHHHHCCCCCCHHHHHHHHHEEECCCCCEEEEECCCCHH
AYRESLFKQEGKGRYVIVSVVFALKTHFVPNLGYGDLAAKVAELSAGREATAKDVSDAVC
HHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AIRNSKLPNPNVLGNVGSFFKNPVIGAEKAAALLEQHPDMPHYPQPDGSVKLAAGWLIDQ
HHHCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHH
CRLKGFQIGGAAVHGRQALVLVNKNNASANDVRQLAQHIKFTVFARFQVELHAEPNWLPA
HHHCEEEECCEEECCCEEEEEEECCCCCHHHHHHHHHHCEEEEEEEEEEEEECCCCCCCC
SFSL
CCCC
>Mature Secondary Structure
MNFPSYLGQPQTYFKVQTMQPIRYRTDLTPYNTFGLRAQARAFIALEHADGLRDIVRLPE
CCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCCEECEEEEEEECCCCHHHHHHCCC
FDRDTVLWLGGGSNILLMQDYAGLVVHMENKGIREIARSDGMVLIEAQAGEIWHDFVLHT
CCCCEEEEEECCCCEEEEECCCCEEEEECCCCHHHHHHCCCEEEEEECCCHHHHHHHHHH
VALGLSGLENLSLIPGTVGASPVQNIGAYGVEAKDVIHSVRCFDLDTETFVTLSNADCRF
HHHHHCCCCCCEECCCCCCCCHHHHHCCCCCCHHHHHHHHHEEECCCCCEEEEECCCCHH
AYRESLFKQEGKGRYVIVSVVFALKTHFVPNLGYGDLAAKVAELSAGREATAKDVSDAVC
HHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AIRNSKLPNPNVLGNVGSFFKNPVIGAEKAAALLEQHPDMPHYPQPDGSVKLAAGWLIDQ
HHHCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHH
CRLKGFQIGGAAVHGRQALVLVNKNNASANDVRQLAQHIKFTVFARFQVELHAEPNWLPA
HHHCEEEECCEEECCCEEEEEEECCCCCHHHHHHHHHHCEEEEEEEEEEEEECCCCCCCC
SFSL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA