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The map label for this gene is hfq [H]

Identifier: 161869692

GI number: 161869692

Start: 719418

End: 719864

Strand: Reverse

Name: hfq [H]

Synonym: NMCC_0712

Alternate gene names: 161869692

Gene position: 719864-719418 (Counterclockwise)

Preceding gene: 161869693

Following gene: 161869691

Centisome position: 33.43

GC content: 47.43

Gene sequence:

>447_bases
GTGGATGCTGCAGCAACGCTCCTGACATACAAATGCCCGGCGGAAAACCGCCCAAACACAAAAAAAATTGGTAATTTTTC
CTATTCAAGGCTACAATTCGACACGCACAGGGCGTCTGCCCGATTTCACAATCATAATAGCGGAGTTAAAAATATGACAG
CTAAAGGACAAATGTTGCAAGATCCCTTCCTGAACGCCCTGCGTAAAGAGCATGTTCCGGTTTCGATTTACTTAGTTAAC
GGTATCAAATTGCAAGGTCAGGTTGAGTCTTTCGATCAATACGTTGTTCTCCTGAGAAACACTTCCGTCACCCAAATGGT
TTACAAACACGCCATTTCCACCATCGTACCGGCACGCTCCGTCAACCTACAACATGAAAACAGACCCCAAGCCGCACCGA
CTTCGACCCTCGTCCAAGTGGAAACCGTCCAGCAGCCTGCCGAATAA

Upstream 100 bases:

>100_bases
TGGTTGTCAAAGCCAACATTCAAAATCAACCCGTTACCATCGTATTGCTGAACTCGCCCACATCCGCCACACGCGTCAAC
GACGCCCGCAAAATCGAATC

Downstream 100 bases:

>100_bases
TCCGCACGAAGCATGACGTGTCATATCTTTCAATACCTTACCGGACAACGGTAAGGTATTTTTATTTTCAGACAGCATTT
AAAAATGTTATTGCAAAACA

Product: host factor-I protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MDAAATLLTYKCPAENRPNTKKIGNFSYSRLQFDTHRASARFHNHNSGVKNMTAKGQMLQDPFLNALRKEHVPVSIYLVN
GIKLQGQVESFDQYVVLLRNTSVTQMVYKHAISTIVPARSVNLQHENRPQAAPTSTLVQVETVQQPAE

Sequences:

>Translated_148_residues
MDAAATLLTYKCPAENRPNTKKIGNFSYSRLQFDTHRASARFHNHNSGVKNMTAKGQMLQDPFLNALRKEHVPVSIYLVN
GIKLQGQVESFDQYVVLLRNTSVTQMVYKHAISTIVPARSVNLQHENRPQAAPTSTLVQVETVQQPAE
>Mature_148_residues
MDAAATLLTYKCPAENRPNTKKIGNFSYSRLQFDTHRASARFHNHNSGVKNMTAKGQMLQDPFLNALRKEHVPVSIYLVN
GIKLQGQVESFDQYVVLLRNTSVTQMVYKHAISTIVPARSVNLQHENRPQAAPTSTLVQVETVQQPAE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=82, Percent_Identity=71.9512195121951, Blast_Score=121, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 16604; Mature: 16604

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAATLLTYKCPAENRPNTKKIGNFSYSRLQFDTHRASARFHNHNSGVKNMTAKGQMLQ
CCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHEECCCCCCCCCCCCCCCCHH
DPFLNALRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLRNTSVTQMVYKHAISTIVPARS
HHHHHHHHHCCCCEEEEEECCEEEECCHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCC
VNLQHENRPQAAPTSTLVQVETVQQPAE
CCCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MDAAATLLTYKCPAENRPNTKKIGNFSYSRLQFDTHRASARFHNHNSGVKNMTAKGQMLQ
CCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHEECCCCCCCCCCCCCCCCHH
DPFLNALRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLRNTSVTQMVYKHAISTIVPARS
HHHHHHHHHCCCCEEEEEECCEEEECCHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCC
VNLQHENRPQAAPTSTLVQVETVQQPAE
CCCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA