Click here to switch to the map view.

The map label for this gene is mlaC [H]

Identifier: 161869247

GI number: 161869247

Start: 268330

End: 268920

Strand: Direct

Name: mlaC [H]

Synonym: NMCC_0252

Alternate gene names: 161869247

Gene position: 268330-268920 (Clockwise)

Preceding gene: 161869246

Following gene: 161869248

Centisome position: 12.46

GC content: 52.28

Gene sequence:

>591_bases
ATGAAAAAATCCTCCCTCATCAGCGCATTGGGCATCGGTATTTTGAGCATCGGCATGGCATTTGCCGCTCCTGCCGACGC
GGTAAACCAAATCCGTCAAAACGCCACTCAAGTATTGAGCATCTTAAAAAGCGGTGATGCCAACACCGCCCGCCAAAAAG
CCGAAGCCTATGCGATTCCCTATTTCGATTTCCAACGTATGACCGCATTGGCGGTCGGCAACCCTTGGCGCACCGCGTCC
GACGCGCAAAAACAAGCGTTGGCCAAAGAATTTCAAACCCTGCTGATCCGCACCTATTCCGGCACGATGCTGAAATTAAA
AAACGCCAACGTCAACGTCAAAGACAATCCCATCGTCAATAAAGGCGGCAAAGAAATCATCGTCCGCGCCGAAGTCGGCG
TACCCGGGCAAAAACCCGTCAACATGGACTTCACCACCTACCAAAGCGGTGGTAAATACCGTACCTACAACGTCGCCATC
GAAGGCGCGAGCCTGGTTACCGTGTACCGCAACCAATTCGGCGAAATCATCAAAGCGAAAGGCGTGGACGGACTGATTGC
CGAGTTGAAGGCTAAAAACGGCAGCAAGTAA

Upstream 100 bases:

>100_bases
ATTCATGACGAGTTTTGCCGAGAAAAATGCCGACGGCGGCAATGCGGAAAAAGCCGCCGAATAAACGTATGCCATCATAT
TCAAACTAGGACACTTAATT

Downstream 100 bases:

>100_bases
TCCATAAGCCATGCCGCCAGACTGAAGATGGCATGGATTTTTTCCTACCGAACACTATGCATACAGAACTCAACAACGGA
ACACTGCACATCAGCGGCGA

Product: periplasmic transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKKSSLISALGIGILSIGMAFAAPADAVNQIRQNATQVLSILKSGDANTARQKAEAYAIPYFDFQRMTALAVGNPWRTAS
DAQKQALAKEFQTLLIRTYSGTMLKLKNANVNVKDNPIVNKGGKEIIVRAEVGVPGQKPVNMDFTTYQSGGKYRTYNVAI
EGASLVTVYRNQFGEIIKAKGVDGLIAELKAKNGSK

Sequences:

>Translated_196_residues
MKKSSLISALGIGILSIGMAFAAPADAVNQIRQNATQVLSILKSGDANTARQKAEAYAIPYFDFQRMTALAVGNPWRTAS
DAQKQALAKEFQTLLIRTYSGTMLKLKNANVNVKDNPIVNKGGKEIIVRAEVGVPGQKPVNMDFTTYQSGGKYRTYNVAI
EGASLVTVYRNQFGEIIKAKGVDGLIAELKAKNGSK
>Mature_196_residues
MKKSSLISALGIGILSIGMAFAAPADAVNQIRQNATQVLSILKSGDANTARQKAEAYAIPYFDFQRMTALAVGNPWRTAS
DAQKQALAKEFQTLLIRTYSGTMLKLKNANVNVKDNPIVNKGGKEIIVRAEVGVPGQKPVNMDFTTYQSGGKYRTYNVAI
EGASLVTVYRNQFGEIIKAKGVDGLIAELKAKNGSK

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=143, Percent_Identity=27.972027972028, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 21114; Mature: 21114

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSSLISALGIGILSIGMAFAAPADAVNQIRQNATQVLSILKSGDANTARQKAEAYAIP
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECC
YFDFQRMTALAVGNPWRTASDAQKQALAKEFQTLLIRTYSGTMLKLKNANVNVKDNPIVN
CCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
KGGKEIIVRAEVGVPGQKPVNMDFTTYQSGGKYRTYNVAIEGASLVTVYRNQFGEIIKAK
CCCCEEEEEEECCCCCCCCCCCCEEEECCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHC
GVDGLIAELKAKNGSK
CCCHHHHHHHCCCCCC
>Mature Secondary Structure
MKKSSLISALGIGILSIGMAFAAPADAVNQIRQNATQVLSILKSGDANTARQKAEAYAIP
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECC
YFDFQRMTALAVGNPWRTASDAQKQALAKEFQTLLIRTYSGTMLKLKNANVNVKDNPIVN
CCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
KGGKEIIVRAEVGVPGQKPVNMDFTTYQSGGKYRTYNVAIEGASLVTVYRNQFGEIIKAK
CCCCEEEEEEECCCCCCCCCCCCEEEECCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHC
GVDGLIAELKAKNGSK
CCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]