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The map label for this gene is zraR [H]

Identifier: 161525389

GI number: 161525389

Start: 2435196

End: 2436584

Strand: Reverse

Name: zraR [H]

Synonym: Bmul_2219

Alternate gene names: 161525389

Gene position: 2436584-2435196 (Counterclockwise)

Preceding gene: 161525392

Following gene: 161525388

Centisome position: 70.66

GC content: 68.18

Gene sequence:

>1389_bases
ATGGGAGCCGAGCAGCGGCATGTGATCTATTATTCGCGCGAGCCGGACGACGCATTGCGCGGTCATTTCGACGACTGCGG
CTGGCGCGTCGATCTCGCGGAGACCGTACGCGACGTACGGCGCGTCGTGCAGCAGGGCGTCGCCACCGCAGGATTCCTCG
ATTTCTCGCCGGGCTTCAAGCCCGCGGAGCTGCGCGAGCTGGAGTCGTGCCTGAGCATCCAGCACGTCGGCTGGATCGCG
GCAACGTGTCGCGGCCAGTTGCAGGACCCGATGCTGCGGCATGTGATCCGCGATTACTGTTTCGACTATGTGACGATGCC
GTACGAGACCGCGCGCATCGTGGAAACGGTCGGGCATGCGCACGGCATGATTGCACTGAGCGATCCGGTCGCGTCCGGCG
GGCGCGGCGAAGGCGAGATGGTCGGCACGTGCGACGCGATGCTCGCGTTGTTCAAGACCATCCGGCGCGTCGCGATGACC
GACGCGCCGGTTTTCATTTCCGGCGAATCGGGTACCGGCAAGGAACTCACGGCCGTTGCGATTCACGAACGCTCGGCGCG
TGGGCACGCGCCGTTCGTCGCGATCAATTGCGGCGCGATTCCGGCGACGCTGCTGCAGGCCGAACTGTTCGGCTACGAGC
GCGGCGCCTTCACGGGCGCGAACCAGCGCAAGATCGGGCGTGTCGAAGCCGCGAACGGCGGCACGCTGTTTCTCGACGAG
ATCGGCGATCTGCCGCTCGAGAGCCAGGCGAGCCTGCTGCGCTTCCTGCAGGAAGGGAAGATCGAACGGCTCGGCGCGCA
TGCGTCGGTGCCGGTCGACGTGCGCGTGATCTGCGCGACGCACGTCGACATGGAGGCGGCGCTGCGCGAAGGCCGGTTCC
GCGAGGATCTGTTTCATCGTCTCTGCGTGCTGAAGATCGAGGAACCGCCGCTGCGCGCGCGCGGCCGCGATATCGAGGTG
CTCGCGCGCCACATGCTCGAGCGTTTCAAGGGCGACGCGCATCGTCGCCTGCGCGGGTTCTCGCCCGATGCGGTCGCGGC
GCTGTACGGCTATGCGTGGCCCGGCAACGTGCGCGAGCTGATCAACCGCGTGCGGCGCGCGATCGTGATGTCGGAAGGCC
GGACGATCACCGCGGCCGATCTCGAGCTGAACGACTATGCGGCGCTCGCGCCGGTGTCGCTCGTCGAGGCGCGCGAAGCG
GCCGAGCGGCAGGCGATCGAGCAGGCGCTGCTGCGGCATCGCGGCCGTTTCGCGGACGCAGCGCGCGAACTGGGCGTGTC
GCGCGTGACGCTGTATCGGCTGATGTGTGCACACGGGATGCGCGACCGCGGCGACACGCTCGCGCCGTTTTCGCCGCCGC
CGCCGGAGCTTCCTCGCCACGCTTGCTAA

Upstream 100 bases:

>100_bases
GCCTGCTGTTGCCGCGCATCGGGCCGGGCCCGATTCGAATTTTTCGCACGTGACGTGCGTGCGCGGCAATCGTTACACGG
TGGACGAACGGGGTGAGCAT

Downstream 100 bases:

>100_bases
AATCTGCGGGTACGGCCGCCCTCGCGGCCGAAGGAACCCGCATGAAACAGTATCTCGACCTCGTTCGCACCATCCTCGAC
ACCGGCACCTGGCAGGAGAA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MGAEQRHVIYYSREPDDALRGHFDDCGWRVDLAETVRDVRRVVQQGVATAGFLDFSPGFKPAELRELESCLSIQHVGWIA
ATCRGQLQDPMLRHVIRDYCFDYVTMPYETARIVETVGHAHGMIALSDPVASGGRGEGEMVGTCDAMLALFKTIRRVAMT
DAPVFISGESGTGKELTAVAIHERSARGHAPFVAINCGAIPATLLQAELFGYERGAFTGANQRKIGRVEAANGGTLFLDE
IGDLPLESQASLLRFLQEGKIERLGAHASVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGRDIEV
LARHMLERFKGDAHRRLRGFSPDAVAALYGYAWPGNVRELINRVRRAIVMSEGRTITAADLELNDYAALAPVSLVEAREA
AERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAPFSPPPPELPRHAC

Sequences:

>Translated_462_residues
MGAEQRHVIYYSREPDDALRGHFDDCGWRVDLAETVRDVRRVVQQGVATAGFLDFSPGFKPAELRELESCLSIQHVGWIA
ATCRGQLQDPMLRHVIRDYCFDYVTMPYETARIVETVGHAHGMIALSDPVASGGRGEGEMVGTCDAMLALFKTIRRVAMT
DAPVFISGESGTGKELTAVAIHERSARGHAPFVAINCGAIPATLLQAELFGYERGAFTGANQRKIGRVEAANGGTLFLDE
IGDLPLESQASLLRFLQEGKIERLGAHASVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGRDIEV
LARHMLERFKGDAHRRLRGFSPDAVAALYGYAWPGNVRELINRVRRAIVMSEGRTITAADLELNDYAALAPVSLVEAREA
AERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAPFSPPPPELPRHAC
>Mature_461_residues
GAEQRHVIYYSREPDDALRGHFDDCGWRVDLAETVRDVRRVVQQGVATAGFLDFSPGFKPAELRELESCLSIQHVGWIAA
TCRGQLQDPMLRHVIRDYCFDYVTMPYETARIVETVGHAHGMIALSDPVASGGRGEGEMVGTCDAMLALFKTIRRVAMTD
APVFISGESGTGKELTAVAIHERSARGHAPFVAINCGAIPATLLQAELFGYERGAFTGANQRKIGRVEAANGGTLFLDEI
GDLPLESQASLLRFLQEGKIERLGAHASVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGRDIEVL
ARHMLERFKGDAHRRLRGFSPDAVAALYGYAWPGNVRELINRVRRAIVMSEGRTITAADLELNDYAALAPVSLVEAREAA
ERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAPFSPPPPELPRHAC

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=358, Percent_Identity=40.2234636871508, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1790437, Length=350, Percent_Identity=43.1428571428571, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI1790299, Length=378, Percent_Identity=40.7407407407407, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1788905, Length=344, Percent_Identity=40.6976744186046, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI87082117, Length=328, Percent_Identity=42.9878048780488, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789233, Length=313, Percent_Identity=43.1309904153355, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789087, Length=322, Percent_Identity=39.7515527950311, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=42.6791277258567, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1786524, Length=315, Percent_Identity=44.1269841269841, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=43.1623931623932, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787583, Length=316, Percent_Identity=36.7088607594937, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=33.4470989761092, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789828, Length=250, Percent_Identity=35.2, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51052; Mature: 50921

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAEQRHVIYYSREPDDALRGHFDDCGWRVDLAETVRDVRRVVQQGVATAGFLDFSPGFK
CCCCCCEEEEEECCCCHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCHHCCCEECCCCCC
PAELRELESCLSIQHVGWIAATCRGQLQDPMLRHVIRDYCFDYVTMPYETARIVETVGHA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HGMIALSDPVASGGRGEGEMVGTCDAMLALFKTIRRVAMTDAPVFISGESGTGKELTAVA
CCEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEE
IHERSARGHAPFVAINCGAIPATLLQAELFGYERGAFTGANQRKIGRVEAANGGTLFLDE
EECCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEEEC
IGDLPLESQASLLRFLQEGKIERLGAHASVPVDVRVICATHVDMEAALREGRFREDLFHR
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEEHHCCHHHHHHCCCHHHHHHHH
LCVLKIEEPPLRARGRDIEVLARHMLERFKGDAHRRLRGFSPDAVAALYGYAWPGNVREL
HHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHCCCCCCHHHHH
INRVRRAIVMSEGRTITAADLELNDYAALAPVSLVEAREAAERQAIEQALLRHRGRFADA
HHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ARELGVSRVTLYRLMCAHGMRDRGDTLAPFSPPPPELPRHAC
HHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GAEQRHVIYYSREPDDALRGHFDDCGWRVDLAETVRDVRRVVQQGVATAGFLDFSPGFK
CCCCCEEEEEECCCCHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCHHCCCEECCCCCC
PAELRELESCLSIQHVGWIAATCRGQLQDPMLRHVIRDYCFDYVTMPYETARIVETVGHA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HGMIALSDPVASGGRGEGEMVGTCDAMLALFKTIRRVAMTDAPVFISGESGTGKELTAVA
CCEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEE
IHERSARGHAPFVAINCGAIPATLLQAELFGYERGAFTGANQRKIGRVEAANGGTLFLDE
EECCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEEEC
IGDLPLESQASLLRFLQEGKIERLGAHASVPVDVRVICATHVDMEAALREGRFREDLFHR
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEEHHCCHHHHHHCCCHHHHHHHH
LCVLKIEEPPLRARGRDIEVLARHMLERFKGDAHRRLRGFSPDAVAALYGYAWPGNVREL
HHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHCCCCCCHHHHH
INRVRRAIVMSEGRTITAADLELNDYAALAPVSLVEAREAAERQAIEQALLRHRGRFADA
HHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ARELGVSRVTLYRLMCAHGMRDRGDTLAPFSPPPPELPRHAC
HHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]