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The map label for this gene is fabD [H]

Identifier: 161525214

GI number: 161525214

Start: 2238770

End: 2239702

Strand: Reverse

Name: fabD [H]

Synonym: Bmul_2044

Alternate gene names: 161525214

Gene position: 2239702-2238770 (Counterclockwise)

Preceding gene: 161525215

Following gene: 161525213

Centisome position: 64.95

GC content: 75.88

Gene sequence:

>933_bases
ATGACGCTCGCGATCCTTTGTTCGGGGCAGGGCGCGCAGCGCGCCGACATGTTCGCGCTGCCGGGCGCGGCGCCGCAGGC
CGACGCGCTGTTCGCCCACGCGGGCCGGCTGCTCGGCGACGATCCGCGCGTGTGGGTGCGCGACGCCGCGCCGGATGCGC
TGCGCGAGAACCGCGCCGCGCAGATCCTCTGTACGGTGCAGGCGCTTGCGGCGGCCGCGCTGCTCGACGCGCTGTGGCCG
CGCCGGCGCTGCGTTGTCGGCTACAGCGTCGGCGAAGTGGCATCGTGGAGCGTCGCCGGCAGTCTCGATCCGCACGACGC
GCTCGATCTCGCGGACGCGCGCGCACGCGCCATGGACGCCGCGAGCGGCGGCGACGAGCGCATGGCGTTCGTGCGCGGCT
TGTCGCGTGCGCAGCTCGCTGCGCTGTGCGACGGGCGCGAGGCGGCGATCGCCATCGCGAACCCGGGCGATGCGTTCGTG
ATCGCGGGCCGGCAGGCGGATGTCGATGCGGTCGCCGCCGACGCGGTGCGCGACGGCGCGCAGCGCGTCGCGCCGGTCTG
CGTGCGGATTGCGTCGCACACGCGGCGCCTGGCCTCCGCGGTGCCCGTATTCCGCGCGTCGCTCGCGGCCGTGCGCGTGC
AACGGCCGCTTGCCGGCACGCGGCTGTTGTCGGGCATCGACGGCGCATCGGTGCTCGACGTCGACGCGGGCCTCGACAAG
CTCGCCCGGCAGATCGCCGAGCCGGTCGAGTGGGCGGCGTGTCTTGCCGCATGCGTCGAAGCGGGCGCGACCGCGTTTCT
CGAACTGGGGCCGGGCCGCGCGCTCGCCGACATGGCGAGCGGCGCCTACCCGGCGCTGCCGGCGCGCAGCCTCGCCGATT
TCCGCTCGATCGACGGCGTCGCGCAGTGGCTCGCGCGCGTCGCCGCGCGCTGA

Upstream 100 bases:

>100_bases
ATCGCGCGTTCGTCGCGCGACGGCTGAGCCCCGGCGGCGCGGCCGACCTGCTCGCGATGAGCCTCTTCGTCGATGGATTC
GACACCGGCGAGGGCGCGCG

Downstream 100 bases:

>100_bases
TCGGGCGCGTCGCAACGCACGCATCGCCACTCGCGCGCGGCCGAGTGTTGCGTCGGCGCAGCAGCGTCGCGACGCGCGCT
TGCCACGCGATTCGGCATCG

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTLAILCSGQGAQRADMFALPGAAPQADALFAHAGRLLGDDPRVWVRDAAPDALRENRAAQILCTVQALAAAALLDALWP
RRRCVVGYSVGEVASWSVAGSLDPHDALDLADARARAMDAASGGDERMAFVRGLSRAQLAALCDGREAAIAIANPGDAFV
IAGRQADVDAVAADAVRDGAQRVAPVCVRIASHTRRLASAVPVFRASLAAVRVQRPLAGTRLLSGIDGASVLDVDAGLDK
LARQIAEPVEWAACLAACVEAGATAFLELGPGRALADMASGAYPALPARSLADFRSIDGVAQWLARVAAR

Sequences:

>Translated_310_residues
MTLAILCSGQGAQRADMFALPGAAPQADALFAHAGRLLGDDPRVWVRDAAPDALRENRAAQILCTVQALAAAALLDALWP
RRRCVVGYSVGEVASWSVAGSLDPHDALDLADARARAMDAASGGDERMAFVRGLSRAQLAALCDGREAAIAIANPGDAFV
IAGRQADVDAVAADAVRDGAQRVAPVCVRIASHTRRLASAVPVFRASLAAVRVQRPLAGTRLLSGIDGASVLDVDAGLDK
LARQIAEPVEWAACLAACVEAGATAFLELGPGRALADMASGAYPALPARSLADFRSIDGVAQWLARVAAR
>Mature_309_residues
TLAILCSGQGAQRADMFALPGAAPQADALFAHAGRLLGDDPRVWVRDAAPDALRENRAAQILCTVQALAAAALLDALWPR
RRCVVGYSVGEVASWSVAGSLDPHDALDLADARARAMDAASGGDERMAFVRGLSRAQLAALCDGREAAIAIANPGDAFVI
AGRQADVDAVAADAVRDGAQRVAPVCVRIASHTRRLASAVPVFRASLAAVRVQRPLAGTRLLSGIDGASVLDVDAGLDKL
ARQIAEPVEWAACLAACVEAGATAFLELGPGRALADMASGAYPALPARSLADFRSIDGVAQWLARVAAR

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=292, Percent_Identity=28.4246575342466, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=27.5409836065574, Blast_Score=78, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24665753, Length=304, Percent_Identity=28.6184210526316, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32001; Mature: 31870

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAILCSGQGAQRADMFALPGAAPQADALFAHAGRLLGDDPRVWVRDAAPDALRENRAA
CEEEEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCHH
QILCTVQALAAAALLDALWPRRRCVVGYSVGEVASWSVAGSLDPHDALDLADARARAMDA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHC
ASGGDERMAFVRGLSRAQLAALCDGREAAIAIANPGDAFVIAGRQADVDAVAADAVRDGA
CCCCHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHH
QRVAPVCVRIASHTRRLASAVPVFRASLAAVRVQRPLAGTRLLSGIDGASVLDVDAGLDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEHHHHHHH
LARQIAEPVEWAACLAACVEAGATAFLELGPGRALADMASGAYPALPARSLADFRSIDGV
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHH
AQWLARVAAR
HHHHHHHHCC
>Mature Secondary Structure 
TLAILCSGQGAQRADMFALPGAAPQADALFAHAGRLLGDDPRVWVRDAAPDALRENRAA
EEEEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCHH
QILCTVQALAAAALLDALWPRRRCVVGYSVGEVASWSVAGSLDPHDALDLADARARAMDA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHC
ASGGDERMAFVRGLSRAQLAALCDGREAAIAIANPGDAFVIAGRQADVDAVAADAVRDGA
CCCCHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHH
QRVAPVCVRIASHTRRLASAVPVFRASLAAVRVQRPLAGTRLLSGIDGASVLDVDAGLDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEHHHHHHH
LARQIAEPVEWAACLAACVEAGATAFLELGPGRALADMASGAYPALPARSLADFRSIDGV
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHH
AQWLARVAAR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]