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The map label for this gene is mdcB [H]

Identifier: 161525215

GI number: 161525215

Start: 2239699

End: 2240568

Strand: Reverse

Name: mdcB [H]

Synonym: Bmul_2045

Alternate gene names: 161525215

Gene position: 2240568-2239699 (Counterclockwise)

Preceding gene: 161525216

Following gene: 161525214

Centisome position: 64.97

GC content: 74.83

Gene sequence:

>870_bases
ATGAGCGCCGCAGCCGTTTGTCGCGCGCCGGCCGCATCCTGGTCGGACGCCGACCGTATCGCGGCGCTCGCCGAGCGCAG
CCTCGTGCTCGAAATCGAAACCTATCCGAAGCCGGGGCTCGTCAGCCACGTCGATACGGGTAGCCATTCGGACATGGACG
CCGCGACGTTCGCACGCAGCGCGGCCGTGCTACGGCCGTTCTTCGCGGAACTGGCCGACGCGGGCGCGCGCGACGCCGAG
ATGGCCGCGCTGCGCAAGATCGGCCTGCGCGCGGAGCATGCGATGCTCGCCGCGACGGGCGGCGTCAACACGCATCGCGG
CGCGATCTTCGGGCTCGGGCTGCTGTGCGCGGCGGCCGGCGCCCGCGCGCGTGCCGAGGCAGCCGGTACGCCTACGCTCG
GCGCGTGGGTTGCGCGCCGCTGGGGCGCCGACATTCTCGGCGGCCCGCGGCTGCCCGACAGCCACGGCGAACGCGCGAGC
CGCCGCTACGGCGTCGGCGGCGCACGCCGCGAAGCCGCCGACGGCTTTGCGACCGTCTACGGCATCGGTTTGCCTGCACT
ACGGCGCGCGGCACGCGACGTCCCGGACGATCCCGAGGCCGCGCGCGTCGATGCGTGCTTCGCGCTGATCGCCGCGCTCG
ACGACACGAACCTGCTGCATCGCGGCGGCCAGGACGGCCTCGATTTCGCCCGCGCGACCGCGCGCGCGTTCGTCGCACGC
GGCGGCGTGCGCGCGCGTGACTGGCGCCGGCACGCGGTGGCCGCGCATCGCGCGTTCGTCGCGCGACGGCTGAGCCCCGG
CGGCGCGGCCGACCTGCTCGCGATGAGCCTCTTCGTCGATGGATTCGACACCGGCGAGGGCGCGCGATGA

Upstream 100 bases:

>100_bases
TCAACTGGCGCGAACTGCAGGCGCGCTTGCCCGAAGTCGCGGTGAAGACGGCGATCGCCGTCGAGCTAATGCCCGCGGCC
GCGTTTGGCGGAGACGCGCG

Downstream 100 bases:

>100_bases
CGCTCGCGATCCTTTGTTCGGGGCAGGGCGCGCAGCGCGCCGACATGTTCGCGCTGCCGGGCGCGGCGCCGCAGGCCGAC
GCGCTGTTCGCCCACGCGGG

Product: triphosphoribosyl-dephospho-CoA synthase MdcB

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSAAAVCRAPAASWSDADRIAALAERSLVLEIETYPKPGLVSHVDTGSHSDMDAATFARSAAVLRPFFAELADAGARDAE
MAALRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAGARARAEAAGTPTLGAWVARRWGADILGGPRLPDSHGERAS
RRYGVGGARREAADGFATVYGIGLPALRRAARDVPDDPEAARVDACFALIAALDDTNLLHRGGQDGLDFARATARAFVAR
GGVRARDWRRHAVAAHRAFVARRLSPGGAADLLAMSLFVDGFDTGEGAR

Sequences:

>Translated_289_residues
MSAAAVCRAPAASWSDADRIAALAERSLVLEIETYPKPGLVSHVDTGSHSDMDAATFARSAAVLRPFFAELADAGARDAE
MAALRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAGARARAEAAGTPTLGAWVARRWGADILGGPRLPDSHGERAS
RRYGVGGARREAADGFATVYGIGLPALRRAARDVPDDPEAARVDACFALIAALDDTNLLHRGGQDGLDFARATARAFVAR
GGVRARDWRRHAVAAHRAFVARRLSPGGAADLLAMSLFVDGFDTGEGAR
>Mature_288_residues
SAAAVCRAPAASWSDADRIAALAERSLVLEIETYPKPGLVSHVDTGSHSDMDAATFARSAAVLRPFFAELADAGARDAEM
AALRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAGARARAEAAGTPTLGAWVARRWGADILGGPRLPDSHGERASR
RYGVGGARREAADGFATVYGIGLPALRRAARDVPDDPEAARVDACFALIAALDDTNLLHRGGQDGLDFARATARAFVARG
GVRARDWRRHAVAAHRAFVARRLSPGGAADLLAMSLFVDGFDTGEGAR

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=275, Percent_Identity=36.3636363636364, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 30099; Mature: 29968

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAAVCRAPAASWSDADRIAALAERSLVLEIETYPKPGLVSHVDTGSHSDMDAATFARS
CCCCHHHCCCCCCCCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
AAVLRPFFAELADAGARDAEMAALRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHC
ARARAEAAGTPTLGAWVARRWGADILGGPRLPDSHGERASRRYGVGGARREAADGFATVY
CHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHCCHHHHH
GIGLPALRRAARDVPDDPEAARVDACFALIAALDDTNLLHRGGQDGLDFARATARAFVAR
HCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHH
GGVRARDWRRHAVAAHRAFVARRLSPGGAADLLAMSLFVDGFDTGEGAR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SAAAVCRAPAASWSDADRIAALAERSLVLEIETYPKPGLVSHVDTGSHSDMDAATFARS
CCCHHHCCCCCCCCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
AAVLRPFFAELADAGARDAEMAALRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHC
ARARAEAAGTPTLGAWVARRWGADILGGPRLPDSHGERASRRYGVGGARREAADGFATVY
CHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHCCHHHHH
GIGLPALRRAARDVPDDPEAARVDACFALIAALDDTNLLHRGGQDGLDFARATARAFVAR
HCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHH
GGVRARDWRRHAVAAHRAFVARRLSPGGAADLLAMSLFVDGFDTGEGAR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10561613 [H]