Click here to switch to the map view.

The map label for this gene is hfq [H]

Identifier: 161524895

GI number: 161524895

Start: 1902882

End: 1903613

Strand: Direct

Name: hfq [H]

Synonym: Bmul_1722

Alternate gene names: 161524895

Gene position: 1902882-1903613 (Clockwise)

Preceding gene: 161524893

Following gene: 161524910

Centisome position: 55.18

GC content: 66.8

Gene sequence:

>732_bases
ATGCGCGTTAGCGTCTATAGTGGGTTACGGTTCGACACAATCGCGACTGGGCGCTTCCCGATCGAACAGGGTAGAATCCC
GCCAAACAGATTTGTGACGACCACGCCACACACGCACAACATATTCTCTGACGCAGGCTCCTGCCGCACCTCAATGGCCA
ATCCCGCAGAATCCCATCCGCAAAACGACTTCATCAATTCCGCGCGAAAGGAACGTAAGCGCGTCGAAATCTACCTCGTC
AACGGCATTCGTCTGACCGGGTGTATCGAGTCGTTCGACCAGTATCTGGTGATGCTGCGCACCCCCGTGGGTCTGCAAGG
CATCTACAAGCGTGCGATTTCGACGATCCAGCTCGACACGGGCGGATCGCGCCCCGGCGGCGGTCCGCGCGGCCCGCGCA
CGGGCGGGCGGCCGGGCGGCCGCGAAGGCGGCGGCCACAGCCCGTACGGCTCGCACGGCGGCTCCCGTGAGCCGCGCGAG
GGCTACGGCTCGCGCGAACCGCGTGAAGGTTACGGTTCGCGTGAACCGCGTGAAGGCTACGGGTCGCGCGAGCCGCGCGA
GGGGTATGGTTCCCGTGAGCCGCGCGAAGGTTACGGCGCGCCGCGTGAAAACTACGGTGCGCCGCGCGACGCCGGCGACG
CGTCGGGCGGCGGATCGCCCTCCGATACGCGCGGCAGCAACGGGCCCGTCATCGTGACGCGCCGCCGCCGGATCGTGCCG
GACGGCCAGTAA

Upstream 100 bases:

>100_bases
AGGAAAGACCGGAAAATTCTGCCGAAACGCACGCGGACACGCATATTCGTCCGCGGATATGCGCGGCAGCTGACGTTGGC
CATTTGGCCGCATCGCGCAA

Downstream 100 bases:

>100_bases
AAGCAAAAAGGGCAAGCCGGTCGGCTTGCCCTTCTCTCTTCGGCGCGCTGCGGCGCCACGCGCCGCCGCAGGGTCGGTCA
GTGTGCCGCGCTCGGCAGAC

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRVSVYSGLRFDTIATGRFPIEQGRIPPNRFVTTTPHTHNIFSDAGSCRTSMANPAESHPQNDFINSARKERKRVEIYLV
NGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGGPRGPRTGGRPGGREGGGHSPYGSHGGSREPRE
GYGSREPREGYGSREPREGYGSREPREGYGSREPREGYGAPRENYGAPRDAGDASGGGSPSDTRGSNGPVIVTRRRRIVP
DGQ

Sequences:

>Translated_243_residues
MRVSVYSGLRFDTIATGRFPIEQGRIPPNRFVTTTPHTHNIFSDAGSCRTSMANPAESHPQNDFINSARKERKRVEIYLV
NGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGGPRGPRTGGRPGGREGGGHSPYGSHGGSREPRE
GYGSREPREGYGSREPREGYGSREPREGYGSREPREGYGAPRENYGAPRDAGDASGGGSPSDTRGSNGPVIVTRRRRIVP
DGQ
>Mature_243_residues
MRVSVYSGLRFDTIATGRFPIEQGRIPPNRFVTTTPHTHNIFSDAGSCRTSMANPAESHPQNDFINSARKERKRVEIYLV
NGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGGPRGPRTGGRPGGREGGGHSPYGSHGGSREPRE
GYGSREPREGYGSREPREGYGSREPREGYGSREPREGYGAPRENYGAPRDAGDASGGGSPSDTRGSNGPVIVTRRRRIVP
DGQ

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=56, Percent_Identity=55.3571428571429, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 26331; Mature: 26331

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSVYSGLRFDTIATGRFPIEQGRIPPNRFVTTTPHTHNIFSDAGSCRTSMANPAESHP
CEEECCCCCEEEEEECCCCCHHCCCCCCCCEEECCCCCCHHHHCCCHHHHHCCCCCCCCC
QNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDT
CHHHHHHHHHHHHEEEEEEECCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEECC
GGSRPGGGPRGPRTGGRPGGREGGGHSPYGSHGGSREPREGYGSREPREGYGSREPREGY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
GSREPREGYGSREPREGYGAPRENYGAPRDAGDASGGGSPSDTRGSNGPVIVTRRRRIVP
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
DGQ
CCC
>Mature Secondary Structure
MRVSVYSGLRFDTIATGRFPIEQGRIPPNRFVTTTPHTHNIFSDAGSCRTSMANPAESHP
CEEECCCCCEEEEEECCCCCHHCCCCCCCCEEECCCCCCHHHHCCCHHHHHCCCCCCCCC
QNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDT
CHHHHHHHHHHHHEEEEEEECCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEECC
GGSRPGGGPRGPRTGGRPGGREGGGHSPYGSHGGSREPREGYGSREPREGYGSREPREGY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
GSREPREGYGSREPREGYGAPRENYGAPRDAGDASGGGSPSDTRGSNGPVIVTRRRRIVP
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
DGQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA