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The map label for this gene is ttuB [H]

Identifier: 161524700

GI number: 161524700

Start: 1684163

End: 1685443

Strand: Direct

Name: ttuB [H]

Synonym: Bmul_1527

Alternate gene names: 161524700

Gene position: 1684163-1685443 (Clockwise)

Preceding gene: 161524699

Following gene: 161524701

Centisome position: 48.84

GC content: 66.51

Gene sequence:

>1281_bases
ATGGCAACTAATCTCGCACCCCGCCGCTGGTGGACGATCATGCCGATCGTCTTCATCACCTACAGCCTCGCCTACCTCGA
CCGCGCGAACTACGGGTTCGCGGCGGCGGCCGGCATCAACCAGGATCTCGGGATCGGCAAGGGCCTGTCGTCGCTGATCG
GCGCGCTGTTCTTCCTCGGCTACTTCTTCTTCCAGATTCCCGGCGCGATCTATGCGGAACGCCGCAGCGTGAAGAAGCTC
GTGTTCGTGAGCCTCGTGCTGTGGGGCGCGTGCGCGGCGCTGACCGGCGTGGTCAGCAACATCCCGTCGCTGATGGTGAT
CCGGTTCGTGCTCGGCGTGGTCGAGGCGGCCGTGATGCCGGCGATGCTGATCTACATCAGCAACTGGTTCACGAAGAGCG
AGCGCTCGCGCGCGAACACATTCCTGATCCTCGGCAACCCGGTGACGGTGCTCTGGATGTCGGTCGTGTCGGGCTATCTC
GTGCACGAATTCGGCTGGCGCCACATGTTCATCGCGGAAGGCGTGCCGGCGATCCTCTGGGCCGTGTGCTGGTGGTTCCT
CGTGCAGGACAAGCCCGCGCAGTCGCCGTGGCTGTCCGCGCAGGAAAAGCGCGATCTTGAGACGACGCTCGCGGCCGAGC
AGGCGGCGATCAAGCCGGTGCGCAACTACGGCGAAGCGTTCCGCTCGCCGGCCGTGATCAAGCTCTGCGCGCAGTATTTC
TGCTGGAGCATCGGCGTGTACGGCTTCGTGCTCTGGCTGCCGTCGATCGTGAAGAACGGCTCCGCGCTCGGGATGGTCGC
GACCGGCTGGCTGTCGGCGCTGCCGTATCTCGCCGCGACGATCGCGATGCTCGCCGCATCGTGGGCGTCGGACAAGGTCG
GATCGCGGCGCGGGTTCGTGTGGCCGTTCCTGCTGGTCGGCGCGGCCGCGTTCGCCGCGTCGTTCGCGCTCGGTTCGACG
CACTTCTGGATCTCGTACGCGCTGCTCGTCGTCGCGGGCGCCGCGATGTATGCGCCGTACGGCCCGTTCTTCGCGATCGT
GCCGGAACTGCTGCCGAAGAACGTCGCCGGCGGCGCGATGGCGCTGATCAACAGCATGGGCGCGCTCGGTTCGTTCGTCG
GCTCGTATTTCGTCGGCTATCTGAACGGCGCGACCGGCTCGCCGCTTGCGTCGTATGCGTTCATGAGCGCCGCGCTCGTC
GCCGCCGTGATCCTGACGCTGTCCGTCAAACCCCAGCCGCGCGACGCCCATTCGCTCGCGGCGCCGCTGCAAGGAAAATG
A

Upstream 100 bases:

>100_bases
CGCGCGCATCGCGATGCGCGAAGCCGCAGCAACGCATGCAGCAATCACCCCGATCGACGACGCCGACGCAAGCGCTCCGG
TCGACACAGGAGACACTCTG

Downstream 100 bases:

>100_bases
AAGATGAAGCCTCGTATCGTCGCGTACAAGCCGCTGCCCGATGACGTCCTCGCGTATCTGCGCGAGCATGCGGACGTCGT
GCAGGCCGACGGCGCCGACG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MATNLAPRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGIGKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKL
VFVSLVLWGACAALTGVVSNIPSLMVIRFVLGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYL
VHEFGWRHMFIAEGVPAILWAVCWWFLVQDKPAQSPWLSAQEKRDLETTLAAEQAAIKPVRNYGEAFRSPAVIKLCAQYF
CWSIGVYGFVLWLPSIVKNGSALGMVATGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASFALGST
HFWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPLASYAFMSAALV
AAVILTLSVKPQPRDAHSLAAPLQGK

Sequences:

>Translated_426_residues
MATNLAPRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGIGKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKL
VFVSLVLWGACAALTGVVSNIPSLMVIRFVLGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYL
VHEFGWRHMFIAEGVPAILWAVCWWFLVQDKPAQSPWLSAQEKRDLETTLAAEQAAIKPVRNYGEAFRSPAVIKLCAQYF
CWSIGVYGFVLWLPSIVKNGSALGMVATGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASFALGST
HFWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPLASYAFMSAALV
AAVILTLSVKPQPRDAHSLAAPLQGK
>Mature_425_residues
ATNLAPRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGIGKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKLV
FVSLVLWGACAALTGVVSNIPSLMVIRFVLGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYLV
HEFGWRHMFIAEGVPAILWAVCWWFLVQDKPAQSPWLSAQEKRDLETTLAAEQAAIKPVRNYGEAFRSPAVIKLCAQYFC
WSIGVYGFVLWLPSIVKNGSALGMVATGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASFALGSTH
FWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPLASYAFMSAALVA
AVILTLSVKPQPRDAHSLAAPLQGK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=245, Percent_Identity=24.8979591836735, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI9945322, Length=364, Percent_Identity=24.7252747252747, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI9966811, Length=367, Percent_Identity=25.0681198910082, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI21322234, Length=259, Percent_Identity=27.4131274131274, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI154350196, Length=365, Percent_Identity=23.013698630137, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87082071, Length=369, Percent_Identity=27.9132791327913, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=23.953488372093, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI2367379, Length=283, Percent_Identity=24.3816254416961, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789515, Length=424, Percent_Identity=24.5283018867925, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789152, Length=403, Percent_Identity=22.5806451612903, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17552542, Length=329, Percent_Identity=26.4437689969605, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115533556, Length=362, Percent_Identity=25.1381215469613, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115533554, Length=362, Percent_Identity=25.1381215469613, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17535049, Length=430, Percent_Identity=24.6511627906977, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193205400, Length=261, Percent_Identity=24.904214559387, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560030, Length=282, Percent_Identity=24.113475177305, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=255, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=255, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=334, Percent_Identity=26.0479041916168, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32565916, Length=177, Percent_Identity=23.728813559322, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=275, Percent_Identity=26.5454545454545, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=173, Percent_Identity=24.2774566473988, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17566884, Length=181, Percent_Identity=25.414364640884, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=207, Percent_Identity=26.5700483091787, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323032, Length=222, Percent_Identity=25.2252252252252, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24580790, Length=340, Percent_Identity=25.5882352941176, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45550460, Length=398, Percent_Identity=24.6231155778894, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24655255, Length=349, Percent_Identity=25.5014326647564, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24583789, Length=356, Percent_Identity=23.5955056179775, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24584153, Length=390, Percent_Identity=22.5641025641026, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI20130135, Length=300, Percent_Identity=24.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655271, Length=300, Percent_Identity=24.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573299, Length=300, Percent_Identity=23, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653727, Length=374, Percent_Identity=25.1336898395722, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648416, Length=271, Percent_Identity=24.3542435424354, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356189, Length=271, Percent_Identity=24.3542435424354, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI62484226, Length=282, Percent_Identity=26.241134751773, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641682, Length=281, Percent_Identity=23.8434163701068, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19922400, Length=236, Percent_Identity=22.8813559322034, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654215, Length=236, Percent_Identity=22.8813559322034, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573708, Length=264, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573707, Length=264, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129235, Length=355, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45939; Mature: 45808

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
ATNLAPRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGIGKGLSSLIGALFFLG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
YFFFQIPGAIYAERRSVKKLVFVSLVLWGACAALTGVVSNIPSLMVIRFVLGVVEAAVMP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYLVHEFGWRHMFIAEGVPAILW
HHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHH
AVCWWFLVQDKPAQSPWLSAQEKRDLETTLAAEQAAIKPVRNYGEAFRSPAVIKLCAQYF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CWSIGVYGFVLWLPSIVKNGSALGMVATGWLSALPYLAATIAMLAASWASDKVGSRRGFV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
WPFLLVGAAAFAASFALGSTHFWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAM
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHH
ALINSMGALGSFVGSYFVGYLNGATGSPLASYAFMSAALVAAVILTLSVKPQPRDAHSLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
APLQGK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]