| Definition | Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010084 |
| Length | 3,448,466 |
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The map label for this gene is phbB [H]
Identifier: 161524658
GI number: 161524658
Start: 1637098
End: 1637838
Strand: Direct
Name: phbB [H]
Synonym: Bmul_1485
Alternate gene names: 161524658
Gene position: 1637098-1637838 (Clockwise)
Preceding gene: 161524657
Following gene: 161524659
Centisome position: 47.47
GC content: 63.16
Gene sequence:
>741_bases ATGTCTCAGCGAATTGCGTACGTAACGGGCGGGATGGGCGGCATCGGCACCAGCATCTGCCAGCGTCTGTCGAAAGACGG CTTCAAGGTGGTCGCAGGCTGCGGCCCGAACTCGCCGCGCCGCGTGAAGTGGCTCGAGGAGCAGAAGGCGCTCGGGTTCG ACTTCATCGCGTCGGAAGGCAACGTCGGCGACTGGGACTCCACGAAGGCGGCATTCGACAAGGTCAAGGCCGAAGTCGGC GAAATCGACGTGCTGGTGAACAATGCGGGCATTACGCGCGACGTCGTGTTCCGCAAGATGACGCACGAAGACTGGACTGC CGTCATCGATACCAACCTGACGAGCCTGTTCAACGTGACGAAACAGGTGATCGACGGGATGGTCGAGCGTGGCTGGGGCC GCATCATCAACATTTCGTCGGTGAACGGCCAGAAGGGGCAATTCGGCCAGACCAACTACTCGACCGCAAAGGCCGGCATT CACGGCTTCACGATGGCGCTCGCGCAGGAAGTCGCGACGAAGGGCGTGACCGTCAACACCGTGTCGCCCGGTTATATCGG CACCGACATGGTGAAGGCGATCCGCCCCGACGTGCTCGAGAAGATCGTGGCGACGATTCCGGTGCGCCGTCTCGGCACGC CGGAGGAAATCGGCTCGATCGTCGCGTGGCTCGCGTCGAACGATTCCGGCTTCGCGACGGGCGCCGACTTCTCGCTGAAC GGCGGCCTGCACATGGGCTGA
Upstream 100 bases:
>100_bases GAACCGTATCCCGGTGCCGGCCAGCCCAGCATCGGCCGGCGCCGTGTGAAGTCGGAGGGCGCTTCGGCGGCCCTCGAAAC CCAAAAATGGAGTGAGATTT
Downstream 100 bases:
>100_bases ACCCGCGGGCTGCGCGGATCGAACAGCGCGCGGCCCCGGGCTTTCCGAAGCGCCCCGCCACCCGGTTCCGGGCGGCGGGG ATTCGTCACTTGCGCTACGC
Product: acetyacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 246; Mature: 245
Protein sequence:
>246_residues MSQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEEQKALGFDFIASEGNVGDWDSTKAAFDKVKAEVG EIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGI HGFTMALAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGTPEEIGSIVAWLASNDSGFATGADFSLN GGLHMG
Sequences:
>Translated_246_residues MSQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEEQKALGFDFIASEGNVGDWDSTKAAFDKVKAEVG EIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGI HGFTMALAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGTPEEIGSIVAWLASNDSGFATGADFSLN GGLHMG >Mature_245_residues SQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEEQKALGFDFIASEGNVGDWDSTKAAFDKVKAEVGE IDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIH GFTMALAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGTPEEIGSIVAWLASNDSGFATGADFSLNG GLHMG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=36.3636363636364, Blast_Score=148, Evalue=6e-36, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.520325203252, Blast_Score=131, Evalue=7e-31, Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.2834645669291, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI4504505, Length=249, Percent_Identity=32.1285140562249, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=29.3172690763052, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=30.7086614173228, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=27.8225806451613, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=28.8, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.9352226720648, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=28, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=26.3598326359833, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI59889578, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=28.0487804878049, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI66933014, Length=187, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=33.4928229665072, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=28.8557213930348, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=31.0679611650485, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI150247226, Length=192, Percent_Identity=29.6875, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI40548397, Length=207, Percent_Identity=28.9855072463768, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI214010158, Length=207, Percent_Identity=28.9855072463768, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI214010156, Length=207, Percent_Identity=28.9855072463768, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI22758144, Length=207, Percent_Identity=28.9855072463768, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI22507405, Length=192, Percent_Identity=29.6875, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI19743808, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=27, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI4503817, Length=185, Percent_Identity=28.6486486486486, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=41.9354838709677, Blast_Score=198, Evalue=3e-52, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=36.2549800796813, Blast_Score=145, Evalue=4e-36, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=32.0833333333333, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.5785123966942, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=29.5081967213115, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=32, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.9795918367347, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1787820, Length=232, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=31.8181818181818, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.9166666666667, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=26.4, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=26.7015706806283, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=41.2955465587045, Blast_Score=167, Evalue=5e-42, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=36.9918699186992, Blast_Score=159, Evalue=2e-39, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=32.6771653543307, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=29.6, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=34.1013824884793, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=30.241935483871, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.5546558704453, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI115534694, Length=239, Percent_Identity=28.4518828451883, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI193203115, Length=233, Percent_Identity=29.1845493562232, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI193203117, Length=240, Percent_Identity=28.75, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=27.4900398406374, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=28.7313432835821, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=28.2868525896414, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=30.1960784313725, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=27.6515151515151, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=28.2868525896414, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.8, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538486, Length=246, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562904, Length=252, Percent_Identity=28.1746031746032, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=28.5185185185185, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.9693486590038, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=26.3940520446097, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=29.8850574712644, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17565030, Length=251, Percent_Identity=28.2868525896414, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=26.1194029850746, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=24.9056603773585, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17531453, Length=278, Percent_Identity=26.2589928057554, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI32563809, Length=212, Percent_Identity=23.5849056603774, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17507613, Length=212, Percent_Identity=23.5849056603774, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=26.6917293233083, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI72000259, Length=199, Percent_Identity=27.1356783919598, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17563726, Length=164, Percent_Identity=27.4390243902439, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=31.8548387096774, Blast_Score=107, Evalue=1e-24, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=7e-14, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=35.3413654618474, Blast_Score=139, Evalue=1e-33, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.201581027668, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=28.8, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=29.7619047619048, Blast_Score=104, Evalue=4e-23, Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=31.4516129032258, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=31.496062992126, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=33.0739299610895, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI18859837, Length=230, Percent_Identity=32.1739130434783, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.5303643724696, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=33.1360946745562, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=29.0816326530612, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24581726, Length=177, Percent_Identity=25.4237288135593, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI281364494, Length=199, Percent_Identity=28.1407035175879, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24641388, Length=205, Percent_Identity=32.1951219512195, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI116007234, Length=230, Percent_Identity=28.695652173913, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI21355631, Length=183, Percent_Identity=26.2295081967213, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26258; Mature: 26127
Theoretical pI: Translated: 7.51; Mature: 7.51
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEEQKALGFDFIASEG CCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCC NVGDWDSTKAAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVT CCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCHHEEECCCHHHHHHHH KQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNT HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC VSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGTPEEIGSIVAWLASNDSGFATGADFSLN CCCCCCCHHHHHHHCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEC GGLHMG CCCCCC >Mature Secondary Structure SQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEEQKALGFDFIASEG CCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCC NVGDWDSTKAAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVT CCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCHHEEECCCHHHHHHHH KQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNT HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC VSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGTPEEIGSIVAWLASNDSGFATGADFSLN CCCCCCCHHHHHHHCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEC GGLHMG CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]