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The map label for this gene is pdxH [H]

Identifier: 161523908

GI number: 161523908

Start: 800975

End: 801619

Strand: Reverse

Name: pdxH [H]

Synonym: Bmul_0728

Alternate gene names: 161523908

Gene position: 801619-800975 (Counterclockwise)

Preceding gene: 161523910

Following gene: 161523907

Centisome position: 23.25

GC content: 67.6

Gene sequence:

>645_bases
ATGACGACTCTCGCCGATCTCCGCATCAACTATTCGCGCGCTTCGCTCGACGAAGCCGATGCCGCCCCCGATCCGTTCGC
CCAGTTCGACCGCTGGTTCAACGAGGCGCTGGCCGCCAAGCTTCCGGAGCCGAACACGATGACGCTCGCGACCGTCGGTG
CTGACGGTCGGCCGTCGGCGCGCATCGTGCTCGTCAAGGGCGTCGACGAGCGCGGGTTCGTCTTCTTCACCAACTACGAA
AGCCGCAAGGGCCGCGATCTCGCTGCGCATCCGTACGCGGCGCTGCTGTTCTACTGGATCGAGCTCGAGCGCCAGGTGCG
CATCGAAGGCCGCGTCGAGAAGACGAGCGCCGAGGAAAGCGACCGCTATTTCGCCTCGCGTCCGGTCGGCTCGCGAATCG
GGGCATGGGCGTCCGAGCAGAGTACCGTGATCGACAGCCGCGCGACGCTCGAAGCGCGCGAGAAAGCATTCAGCGAGCGC
TACGGTGACGATCCGCCGCGCCCGCCGCACTGGGGCGGCTATCGCGTCGTGCCCGATACGCTGGAATTCTGGCAGGGCCG
CCCGTCGCGGCTGCACGATCGTCTGGTCTACACGCGCGATGCCGCGGCGCCGCACGGCTGGACGATCTCGCGACTGTCGC
CGTAA

Upstream 100 bases:

>100_bases
GCCTCTATTTTGCCTGATCTCCCCGCCGCGACGCGCCGCTGTGCACGCACGATTCTTCCGCGTTCGCTATACTGGCCCCC
GATTGAAGCGTTTGCATAAC

Downstream 100 bases:

>100_bases
GCGCGGCGCCGGCGTGCGGCCGGCCGCATCACGTGTTGCATCCGGGCGCGTCGCAGCGCGGCGCGCCGGTCAAGATACTT
GGCTGTATTCGATTCAACGA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MTTLADLRINYSRASLDEADAAPDPFAQFDRWFNEALAAKLPEPNTMTLATVGADGRPSARIVLVKGVDERGFVFFTNYE
SRKGRDLAAHPYAALLFYWIELERQVRIEGRVEKTSAEESDRYFASRPVGSRIGAWASEQSTVIDSRATLEAREKAFSER
YGDDPPRPPHWGGYRVVPDTLEFWQGRPSRLHDRLVYTRDAAAPHGWTISRLSP

Sequences:

>Translated_214_residues
MTTLADLRINYSRASLDEADAAPDPFAQFDRWFNEALAAKLPEPNTMTLATVGADGRPSARIVLVKGVDERGFVFFTNYE
SRKGRDLAAHPYAALLFYWIELERQVRIEGRVEKTSAEESDRYFASRPVGSRIGAWASEQSTVIDSRATLEAREKAFSER
YGDDPPRPPHWGGYRVVPDTLEFWQGRPSRLHDRLVYTRDAAAPHGWTISRLSP
>Mature_213_residues
TTLADLRINYSRASLDEADAAPDPFAQFDRWFNEALAAKLPEPNTMTLATVGADGRPSARIVLVKGVDERGFVFFTNYES
RKGRDLAAHPYAALLFYWIELERQVRIEGRVEKTSAEESDRYFASRPVGSRIGAWASEQSTVIDSRATLEAREKAFSERY
GDDPPRPPHWGGYRVVPDTLEFWQGRPSRLHDRLVYTRDAAAPHGWTISRLSP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=201, Percent_Identity=46.7661691542289, Blast_Score=182, Evalue=2e-46,
Organism=Escherichia coli, GI1787926, Length=215, Percent_Identity=43.2558139534884, Blast_Score=184, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17553712, Length=197, Percent_Identity=47.7157360406091, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319509, Length=211, Percent_Identity=46.9194312796209, Blast_Score=186, Evalue=2e-48,
Organism=Drosophila melanogaster, GI45551845, Length=228, Percent_Identity=46.0526315789474, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24644901, Length=228, Percent_Identity=46.0526315789474, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24644903, Length=174, Percent_Identity=27.0114942528736, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24232; Mature: 24101

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLADLRINYSRASLDEADAAPDPFAQFDRWFNEALAAKLPEPNTMTLATVGADGRPSA
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCE
RIVLVKGVDERGFVFFTNYESRKGRDLAAHPYAALLFYWIELERQVRIEGRVEKTSAEES
EEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEECEEECCCCCHH
DRYFASRPVGSRIGAWASEQSTVIDSRATLEAREKAFSERYGDDPPRPPHWGGYRVVPDT
CCEECCCCCCHHHCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCH
LEFWQGRPSRLHDRLVYTRDAAAPHGWTISRLSP
HHHHCCCHHHHHHHEEEECCCCCCCCEEECCCCC
>Mature Secondary Structure 
TTLADLRINYSRASLDEADAAPDPFAQFDRWFNEALAAKLPEPNTMTLATVGADGRPSA
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCE
RIVLVKGVDERGFVFFTNYESRKGRDLAAHPYAALLFYWIELERQVRIEGRVEKTSAEES
EEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEECEEECCCCCHH
DRYFASRPVGSRIGAWASEQSTVIDSRATLEAREKAFSERYGDDPPRPPHWGGYRVVPDT
CCEECCCCCCHHHCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCH
LEFWQGRPSRLHDRLVYTRDAAAPHGWTISRLSP
HHHHCCCHHHHHHHEEEECCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA