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The map label for this gene is kynB

Identifier: 161523900

GI number: 161523900

Start: 793277

End: 793918

Strand: Reverse

Name: kynB

Synonym: Bmul_0720

Alternate gene names: 161523900

Gene position: 793918-793277 (Counterclockwise)

Preceding gene: 161523902

Following gene: 161523899

Centisome position: 23.02

GC content: 72.27

Gene sequence:

>642_bases
ATGGACATACTCTGGGACATCTCCCCGCCCATCAGCGCCGCCACGCCCGTGTGGCCGGGCGACACGCCGGTGTCGGTGGA
GCGCGTCTGGCGGATCGAGGCCGGCTCGCCGGTCAACGTCGCACGGCTGACGCTGTCGCCGCATACCGGCGCGCACTGCG
ACGCGCCGCTGCACTACGATGCCGACGGCGCCGCGATCGGCGCCGTGCCGCTCGACACCTATGTCGGCCCGTGCCGCGTG
ATCCACTGCATCGGCGCGTCGCCGGTCGTGCGGCCGGCCGACGTCGCAGCCGCGCTCGACGGCGTACCGCCGCGCGTGCT
GCTGCGCACGTACGCGAATGCGCCGACCGCGCACTGGGACAGCGCGTTCTGCGCGGTCGCACCGGACACCGTCGATCTGC
TTGCCGCGCACGGCGTGAAGCTGATCGGCATCGACACGCCGTCGCTCGATCCGCAGGAATCGAAGACGATGGACGCGCAC
CACCGCGTGCATGCGCACCGGATGGCGATCCTCGAAGGCATCGTGCTCGACGAGGTGCCGCCCGGCGACTATGAACTGAT
CGCCCTGCCGCTCAAATTCGCGACGCTCGACGCGAGCCCCGTGCGCGCCGTCCTGCGCGCGCTGCCCGCGCGCGCCGCCT
GA

Upstream 100 bases:

>100_bases
TTATCTGCCAATCGGGCGGATTGTCCATGTTTATTTCGCAAGCACTTTCTGCAAGCGTCCGCCTATCATTCGAAGGATCG
ATTCATCGCTTCGTCATGCC

Downstream 100 bases:

>100_bases
TTCTTTCGACCGACGAACCCACCATGATGATCAAGACCCGTGAAGATGCGCTCGCGCTCGATCGCGACGATCCGCTTGCC
CCGTTGCGCAGCCAGTTCGC

Product: arylformamidase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MDILWDISPPISAATPVWPGDTPVSVERVWRIEAGSPVNVARLTLSPHTGAHCDAPLHYDADGAAIGAVPLDTYVGPCRV
IHCIGASPVVRPADVAAALDGVPPRVLLRTYANAPTAHWDSAFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAH
HRVHAHRMAILEGIVLDEVPPGDYELIALPLKFATLDASPVRAVLRALPARAA

Sequences:

>Translated_213_residues
MDILWDISPPISAATPVWPGDTPVSVERVWRIEAGSPVNVARLTLSPHTGAHCDAPLHYDADGAAIGAVPLDTYVGPCRV
IHCIGASPVVRPADVAAALDGVPPRVLLRTYANAPTAHWDSAFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAH
HRVHAHRMAILEGIVLDEVPPGDYELIALPLKFATLDASPVRAVLRALPARAA
>Mature_213_residues
MDILWDISPPISAATPVWPGDTPVSVERVWRIEAGSPVNVARLTLSPHTGAHCDAPLHYDADGAAIGAVPLDTYVGPCRV
IHCIGASPVVRPADVAAALDGVPPRVLLRTYANAPTAHWDSAFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAH
HRVHAHRMAILEGIVLDEVPPGDYELIALPLKFATLDASPVRAVLRALPARAA

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KYNB_BURM1 (A9AGH3)

Other databases:

- EMBL:   CP000868
- EMBL:   AP009385
- RefSeq:   YP_001578912.1
- RefSeq:   YP_001946967.1
- ProteinModelPortal:   A9AGH3
- SMR:   A9AGH3
- GeneID:   5767638
- GeneID:   6358590
- GenomeReviews:   AP009385_GR
- GenomeReviews:   CP000868_GR
- KEGG:   bmj:BMULJ_02540
- KEGG:   bmu:Bmul_0720
- HOGENOM:   HBG686791
- OMA:   CPVNVGR
- ProtClustDB:   CLSK930430
- InterPro:   IPR017484
- InterPro:   IPR007325
- TIGRFAMs:   TIGR03035

Pfam domain/function: PF04199 Cyclase

EC number: =3.5.1.9

Molecular weight: Translated: 22469; Mature: 22469

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILWDISPPISAATPVWPGDTPVSVERVWRIEAGSPVNVARLTLSPHTGAHCDAPLHYD
CCEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEEC
ADGAAIGAVPLDTYVGPCRVIHCIGASPVVRPADVAAALDGVPPRVLLRTYANAPTAHWD
CCCCEEECEEHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
SAFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAHHRVHAHRMAILEGIVLDEVP
CEEEEECCCHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGDYELIALPLKFATLDASPVRAVLRALPARAA
CCCEEEEEEEEEEEECCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDILWDISPPISAATPVWPGDTPVSVERVWRIEAGSPVNVARLTLSPHTGAHCDAPLHYD
CCEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEEC
ADGAAIGAVPLDTYVGPCRVIHCIGASPVVRPADVAAALDGVPPRVLLRTYANAPTAHWD
CCCCEEECEEHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
SAFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAHHRVHAHRMAILEGIVLDEVP
CEEEEECCCHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGDYELIALPLKFATLDASPVRAVLRALPARAA
CCCEEEEEEEEEEEECCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA