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The map label for this gene is gpmA [H]

Identifier: 161523626

GI number: 161523626

Start: 491822

End: 492634

Strand: Reverse

Name: gpmA [H]

Synonym: Bmul_0446

Alternate gene names: 161523626

Gene position: 492634-491822 (Counterclockwise)

Preceding gene: 161523632

Following gene: 161523625

Centisome position: 14.29

GC content: 66.05

Gene sequence:

>813_bases
ATGGCGGACCCGGCTGCGGGCCCCGCGCGACGCGCACCGCTTCCTTCACTACCGACCGCAAGATCCATGTACAAACTCGT
TCTCATCCGCCACGGCGAATCGACGTGGAACAAGGAAAACCGCTTCACCGGCTGGGTCGACGTCGACCTCACCGAACAGG
GTCGCAACGAGGCCTATCAGGCCGGCGAACTGCTCAAGGAAGCCGGCTACACGTTCGACATCGCGTACACGTCGGTGCTC
AAGCGCGCGATCCGCACGCTGTGGCACGTGCAGGACCGGATGGATCTCATGTATCTGCCGGTCGTCCATTCGTGGCGACT
GAACGAGCGCCACTACGGTGCGCTGTCGGGCCTGAACAAGGCTGAAACGGCCGCCAAGTTCGGCGACGACCAGGTGCTCG
TCTGGCGCCGCAGCTACGACACGCCGCCGCCCGCGCTGGAACCGACCGACGAGCGCGCGCCGTACAACGATCCGCGCTAC
GCGAAGGTGCCGCGCGAGCAGCTGCCGCTCACCGAGTGCCTGAAGGACACGGTCGCCCGCGTGCTGCCGCTCTGGAACGA
GTCGATCGCGCCGGCGATCCGCGCGGGCAAGCAGGTGCTGATCGCGGCGCATGGCAATTCGCTGCGCGCGCTCATCAAGT
ACCTCGACGGCATCTCGGACAGCGACATCGTCGGCCTGAACATCCCGAACGGCGTGCCGCTCGTCTACGAACTCGACGAG
AACCTGAAGCCGATCAAGCACTATTACCTCGGCGACCAGGAAGCGATCGCGAAGGCGCAGGCCGCGGTCGCGAAGCAGGG
CAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCAGGTTCGTGTAATCGGTAAAGAACGTCACGGAATTCCGCCGAAAAAAGAGAAATCGGAAAAGGGCAATCCCGCCATTA
TAAAATAACCGTCTTGCGCG

Downstream 100 bases:

>100_bases
CGCCCGTCGCGTCGCGCCGGCCTCCCCGGCGCGGCGTTTCACGGCCGCGCGAACCTTCGCGGGCCGCGCGCTGTCGAATC
CGCTTTCGAAGCCGTCGCGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MADPAAGPARRAPLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVL
KRAIRTLWHVQDRMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPYNDPRY
AKVPREQLPLTECLKDTVARVLPLWNESIAPAIRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
NLKPIKHYYLGDQEAIAKAQAAVAKQGKAG

Sequences:

>Translated_270_residues
MADPAAGPARRAPLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVL
KRAIRTLWHVQDRMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPYNDPRY
AKVPREQLPLTECLKDTVARVLPLWNESIAPAIRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
NLKPIKHYYLGDQEAIAKAQAAVAKQGKAG
>Mature_269_residues
ADPAAGPARRAPLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVLK
RAIRTLWHVQDRMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPYNDPRYA
KVPREQLPLTECLKDTVARVLPLWNESIAPAIRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEN
LKPIKHYYLGDQEAIAKAQAAVAKQGKAG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=254, Percent_Identity=58.6614173228346, Blast_Score=313, Evalue=8e-86,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=62.2489959839357, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=60.6425702811245, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI4502445, Length=256, Percent_Identity=51.5625, Blast_Score=268, Evalue=4e-72,
Organism=Homo sapiens, GI40353764, Length=256, Percent_Identity=51.5625, Blast_Score=268, Evalue=4e-72,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=62.962962962963, Blast_Score=196, Evalue=1e-50,
Organism=Escherichia coli, GI1786970, Length=248, Percent_Identity=64.9193548387097, Blast_Score=331, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=54.0650406504065, Blast_Score=250, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6324516, Length=293, Percent_Identity=31.740614334471, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320183, Length=298, Percent_Identity=31.8791946308725, Blast_Score=145, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24646216, Length=253, Percent_Identity=52.9644268774704, Blast_Score=277, Evalue=4e-75,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=53.6, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=53.6, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=53.6, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=41.0358565737052, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=41.0358565737052, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=41.0358565737052, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 30169; Mature: 30037

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPAAGPARRAPLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQ
CCCCCCCCCCCCCCCCCCCHHHHHEEHEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHH
AGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDRMDLMYLPVVHSWRLNERHYGALSGLNK
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEECHHHCEECCCCHHHHHHCCCH
AETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPYNDPRYAKVPREQLPLTECLKDTVAR
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHH
VLPLWNESIAPAIRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
HHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCC
NLKPIKHYYLGDQEAIAKAQAAVAKQGKAG
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADPAAGPARRAPLPSLPTARSMYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQ
CCCCCCCCCCCCCCCCCCHHHHHEEHEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHH
AGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDRMDLMYLPVVHSWRLNERHYGALSGLNK
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEECHHHCEECCCCHHHHHHCCCH
AETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPYNDPRYAKVPREQLPLTECLKDTVAR
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHH
VLPLWNESIAPAIRAGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDE
HHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCC
NLKPIKHYYLGDQEAIAKAQAAVAKQGKAG
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA