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The map label for this gene is dppA [H]

Identifier: 161523561

GI number: 161523561

Start: 419468

End: 421063

Strand: Reverse

Name: dppA [H]

Synonym: Bmul_0381

Alternate gene names: 161523561

Gene position: 421063-419468 (Counterclockwise)

Preceding gene: 161523562

Following gene: 161523559

Centisome position: 12.21

GC content: 65.29

Gene sequence:

>1596_bases
ATGCAGGTCAAGCTGTTCGCCGCGGCCGCCGTCGCCGCCGCACTCGCCGCCCCCGGCCTCGTCGCGGCCAAGCCGCTCAC
CGTCTGCACCGAGTCGAGCCCGGACGGCTTCGACGTCGTCCAGTACAACTCGCTCGTCACGACCAATGCGTCGGCCGACG
TGATCTTCAACACGCTCGTGTCCTACGACGAAGCCGCGAAGAAGGTCGCGCCGGCGCTCGCCGACAAGTGGGAAGCGAGC
GCGGACGGCCTCACGTACACGTTCCATCTGCGTCCGAACGTCGCGTTCCAGACGACCGACTACTTCAAGCCGAGCCGCCC
GCTCAACGCCGACGACGTCGTGTTCACGTTCAGCCGGATGCTCGACGACGCGAATCCGTGGCACAAGGTCGCCGGCGCGA
GCGGCTTCCCGCACGCGCAGTCGATGGGGCTCGCGAAGCTCGTGAAGTCGGTCTCGAAGGTCGACGATCTGACGGTGAAG
TTCGTGCTGAACGAACCGAACGCGACCTTCGTGCCGATCCTGACGATGGGCTTCGCGTCGATCTACTCGGCCGAATACGC
GGCCCAGCTGCTGAAGGCCGGCAAGCAGTCCGACCTGAACGCGAAGCCGATCGGCACCGGCCCGTTCGTGCTGAAGAGCT
ACACGAAGGACGCGCTGATCCGCTACGACGTGAATCCGTCGTACTGGGGCGCAAAGCCGAAGGTCGACCGGCTCATCTAC
GCGATCACGCCCGATCCGTCGGTTCGCCTGCAGAAGCTGAAGGCCGGCGAATGCCAGATCGCGCTGTCGCCGAAGCCGCA
GGACGTGCTCGCCGCGAAGGGCGAAAGCGCGCTGAAGGTCGTGCAGACGCCCGCGTTCATGACGGCGTTCGTTGCGCTGA
ACACGCAGAAGAAACCGCTCGACAACGCGAAGGTGCGCGAAGCGCTGAACCTCGCGTTCGATCGCGCGACCTACCTGAAG
GTCGTGTTCGACAACACCGCGACGGCCGCCAACAACCCGTATCCGCCGAACACGTGGAGCTACGCGAAGGACGTCGCGCC
GTATCCGTACGATCCGGCAAAGGCGAAACAGCTGCTCGCGCAGGCCGGCTTCGCGAACGGCTTCTCGACGACGATCTGGA
CGCGTCCGACCGGCAGCGTGCTGAACCCGAATCCGAAGGCAGGCGCGGAGCTGCTGCAGGCCGACCTCGCGAAGATCGGC
GTGAAGGCCGACGTGAAGGTCATCGAATGGGGCGAACTGATCAAGCAGGCGAAGCTCGGCCAGCATGACATGCTGTTCAT
GGGCTGGGCCGGCGACAACGGCGATCCGGACAACTATCTGACGCCGCTGTTCAGCTGCAACGCGGTGAAGTCGGGCATCA
ACTTCGCGCGCTTCTGCGATGCGCAGCTCGACAAGCTGATCGCCGACGGCAAGGCGACGGCCGATCAGGGCAAGCGCACG
AAGCTGTACGAATCCGCGCAGAAGATCATTCACGACCAGGCGCTGTGGATTCCGCTCGGCTATCCGACCGCCGCCGCCCT
CACGCGCGCGAACGTCAGCGGCTATCGCGTGAGTCCGTTCGGACGCCAGAACTTCGCGACGGTCGCGGTGCAGTAA

Upstream 100 bases:

>100_bases
CTTTGACGGTATGCTATCCGGCAGCCGCGCCGGCCCGCCGCCGTCATCGCGCGCCGGCCATTCGTCATCCGCAGAACGCA
CAAGTCACGAGGGAGATTCC

Downstream 100 bases:

>100_bases
CGCCGCGGCGCGCGCGGGCAGCGGCTCTCGCCGCTGCAGCGCGACGCGGCCCGTGCACGCGCGAAGCGCGCTCGCTCAGC
GCGCGATGCGGAACCGCAGC

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MQVKLFAAAAVAAALAAPGLVAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVAPALADKWEAS
ADGLTYTFHLRPNVAFQTTDYFKPSRPLNADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLAKLVKSVSKVDDLTVK
FVLNEPNATFVPILTMGFASIYSAEYAAQLLKAGKQSDLNAKPIGTGPFVLKSYTKDALIRYDVNPSYWGAKPKVDRLIY
AITPDPSVRLQKLKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNAKVREALNLAFDRATYLK
VVFDNTATAANNPYPPNTWSYAKDVAPYPYDPAKAKQLLAQAGFANGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIG
VKADVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQGKRT
KLYESAQKIIHDQALWIPLGYPTAAALTRANVSGYRVSPFGRQNFATVAVQ

Sequences:

>Translated_531_residues
MQVKLFAAAAVAAALAAPGLVAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVAPALADKWEAS
ADGLTYTFHLRPNVAFQTTDYFKPSRPLNADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLAKLVKSVSKVDDLTVK
FVLNEPNATFVPILTMGFASIYSAEYAAQLLKAGKQSDLNAKPIGTGPFVLKSYTKDALIRYDVNPSYWGAKPKVDRLIY
AITPDPSVRLQKLKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNAKVREALNLAFDRATYLK
VVFDNTATAANNPYPPNTWSYAKDVAPYPYDPAKAKQLLAQAGFANGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIG
VKADVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQGKRT
KLYESAQKIIHDQALWIPLGYPTAAALTRANVSGYRVSPFGRQNFATVAVQ
>Mature_531_residues
MQVKLFAAAAVAAALAAPGLVAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVAPALADKWEAS
ADGLTYTFHLRPNVAFQTTDYFKPSRPLNADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLAKLVKSVSKVDDLTVK
FVLNEPNATFVPILTMGFASIYSAEYAAQLLKAGKQSDLNAKPIGTGPFVLKSYTKDALIRYDVNPSYWGAKPKVDRLIY
AITPDPSVRLQKLKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNAKVREALNLAFDRATYLK
VVFDNTATAANNPYPPNTWSYAKDVAPYPYDPAKAKQLLAQAGFANGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIG
VKADVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQGKRT
KLYESAQKIIHDQALWIPLGYPTAAALTRANVSGYRVSPFGRQNFATVAVQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=518, Percent_Identity=44.5945945945946, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1787551, Length=527, Percent_Identity=34.3453510436433, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1787052, Length=523, Percent_Identity=31.5487571701721, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1787762, Length=481, Percent_Identity=26.1954261954262, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789887, Length=509, Percent_Identity=27.1119842829077, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1787495, Length=536, Percent_Identity=23.8805970149254, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081878, Length=488, Percent_Identity=25.8196721311475, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789397, Length=493, Percent_Identity=25.7606490872211, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57285; Mature: 57285

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKLFAAAAVAAALAAPGLVAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLV
CEEEEHHHHHHHHHHHCCCCEECCCEEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHH
SYDEAAKKVAPALADKWEASADGLTYTFHLRPNVAFQTTDYFKPSRPLNADDVVFTFSRM
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHH
LDDANPWHKVAGASGFPHAQSMGLAKLVKSVSKVDDLTVKFVLNEPNATFVPILTMGFAS
HCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHHCCEEEEEEEECCCCCEEHHHHHHHHH
IYSAEYAAQLLKAGKQSDLNAKPIGTGPFVLKSYTKDALIRYDVNPSYWGAKPKVDRLIY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEE
AITPDPSVRLQKLKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPL
EECCCCCHHHHEECCCCEEEEECCCCHHHHHCCCCCCEEECCCCHHHHHHHEECCCCCCC
DNAKVREALNLAFDRATYLKVVFDNTATAANNPYPPNTWSYAKDVAPYPYDPAKAKQLLA
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHH
QAGFANGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIGVKADVKVIEWGELIKQAKLG
HHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCC
QHDMLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQGKRT
CCCEEEEEECCCCCCCCCHHCHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHH
KLYESAQKIIHDQALWIPLGYPTAAALTRANVSGYRVSPFGRQNFATVAVQ
HHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MQVKLFAAAAVAAALAAPGLVAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLV
CEEEEHHHHHHHHHHHCCCCEECCCEEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHH
SYDEAAKKVAPALADKWEASADGLTYTFHLRPNVAFQTTDYFKPSRPLNADDVVFTFSRM
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHH
LDDANPWHKVAGASGFPHAQSMGLAKLVKSVSKVDDLTVKFVLNEPNATFVPILTMGFAS
HCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHHCCEEEEEEEECCCCCEEHHHHHHHHH
IYSAEYAAQLLKAGKQSDLNAKPIGTGPFVLKSYTKDALIRYDVNPSYWGAKPKVDRLIY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEE
AITPDPSVRLQKLKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPL
EECCCCCHHHHEECCCCEEEEECCCCHHHHHCCCCCCEEECCCCHHHHHHHEECCCCCCC
DNAKVREALNLAFDRATYLKVVFDNTATAANNPYPPNTWSYAKDVAPYPYDPAKAKQLLA
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHH
QAGFANGFSTTIWTRPTGSVLNPNPKAGAELLQADLAKIGVKADVKVIEWGELIKQAKLG
HHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCC
QHDMLFMGWAGDNGDPDNYLTPLFSCNAVKSGINFARFCDAQLDKLIADGKATADQGKRT
CCCEEEEEECCCCCCCCCHHCHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHH
KLYESAQKIIHDQALWIPLGYPTAAALTRANVSGYRVSPFGRQNFATVAVQ
HHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]