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The map label for this gene is ucpA [C]

Identifier: 161523562

GI number: 161523562

Start: 421525

End: 422298

Strand: Reverse

Name: ucpA [C]

Synonym: Bmul_0382

Alternate gene names: 161523562

Gene position: 422298-421525 (Counterclockwise)

Preceding gene: 161523563

Following gene: 161523561

Centisome position: 12.25

GC content: 70.54

Gene sequence:

>774_bases
ATGACTACTCCGCTGAAGGTCTTCATCACCGGCGCGTCGAGCGGCCTCGGCCTCGCGATGGCCGAAGAATACGCCCGCCA
GGGCGCCGTCCTCGCCCTCGTCGCGCGACGCACCGACGTACTCGATGCATTCGCGCGACGCTTTCCGAAACTCTCCGTTT
CCGTCTATCGCGCCGACGTGCGCGATGCCGATGCACTCGCCGCCGCGGCCGCGTCGTTCATCGCCGCGCATGGCTGCCCG
GACGTCGTGATCGCGAACGCCGGCATCAGCCAGGGCGCCGTGACGGGCCAGGGCGATCTCGCCGCGTTCCGCGACGTGAT
GGACATCAACTACTACGGGATGGTCGCGACGTTCGAGCCGTTCGTCGGCCCGATGACGGCCGCGCGCCACGGCACGCTGG
TCGGCGTCGCGAGCGTTGCCGGCGTGCGCGGGCTGCCGGGCTCCGGCGCGTACAGCGCGTCGAAATCGGCGGCGATCAAG
TACCTCGAGGCACTGCGCGTCGAGCTGCGCCCGGCCGGCGTCGCGGTCGTGACGATCGCGCCCGGCTACATCCGCACGCC
GATGACCGCGCACAACCCGTATCCGATGCCGTTCCTGATGGACGCCGACCGGTTCGCCGCCCAGGCGGCCCGCGCGATCG
CGCGCAAGCACGCGTTCCGCGTGATTCCGTGGCAGATGGGCGTCGTCGCGAAGGTGCTGCACGTGCTGCCGCGCTGGCTG
TACGACCGTCTGTTCGAAAGGGCGCCGCGCAAGCCGAGAGCCGGCGCGCACTAA

Upstream 100 bases:

>100_bases
CCCGCCTACACGAACAGCATTCCGGGTACCGCGCAGGTGCTCGACTTCCTCGTGAAGCAGGTTCAGGACAAGAAGCTCTG
ATCCTCGCCCGCGCGCCGGC

Downstream 100 bases:

>100_bases
CGTTCCGCCGCTCGGCGTGCGCGCCGTCGGCTGCCGGCTGTTTCCACACGTAGAAGCCGGCGCGATCGCACGCCGAAGGC
GGGCATGCAACGGCGGCGTC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTTPLKVFITGASSGLGLAMAEEYARQGAVLALVARRTDVLDAFARRFPKLSVSVYRADVRDADALAAAAASFIAAHGCP
DVVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEPFVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIK
YLEALRVELRPAGVAVVTIAPGYIRTPMTAHNPYPMPFLMDADRFAAQAARAIARKHAFRVIPWQMGVVAKVLHVLPRWL
YDRLFERAPRKPRAGAH

Sequences:

>Translated_257_residues
MTTPLKVFITGASSGLGLAMAEEYARQGAVLALVARRTDVLDAFARRFPKLSVSVYRADVRDADALAAAAASFIAAHGCP
DVVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEPFVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIK
YLEALRVELRPAGVAVVTIAPGYIRTPMTAHNPYPMPFLMDADRFAAQAARAIARKHAFRVIPWQMGVVAKVLHVLPRWL
YDRLFERAPRKPRAGAH
>Mature_256_residues
TTPLKVFITGASSGLGLAMAEEYARQGAVLALVARRTDVLDAFARRFPKLSVSVYRADVRDADALAAAAASFIAAHGCPD
VVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEPFVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIKY
LEALRVELRPAGVAVVTIAPGYIRTPMTAHNPYPMPFLMDADRFAAQAARAIARKHAFRVIPWQMGVVAKVLHVLPRWLY
DRLFERAPRKPRAGAH

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=31.6062176165803, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=29.4416243654822, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=28.7958115183246, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI40807363, Length=232, Percent_Identity=30.1724137931034, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4503817, Length=199, Percent_Identity=31.1557788944724, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4758504, Length=201, Percent_Identity=32.8358208955224, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI223718074, Length=189, Percent_Identity=32.2751322751323, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI31543615, Length=226, Percent_Identity=23.0088495575221, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=193, Percent_Identity=32.1243523316062, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=33.1550802139037, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787335, Length=182, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=25.1396648044693, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=242, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=29.3193717277487, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17570069, Length=186, Percent_Identity=31.7204301075269, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=186, Percent_Identity=29.5698924731183, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17507613, Length=191, Percent_Identity=31.413612565445, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=191, Percent_Identity=31.413612565445, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=203, Percent_Identity=29.5566502463054, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=241, Percent_Identity=26.9709543568465, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=188, Percent_Identity=28.1914893617021, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=229, Percent_Identity=29.6943231441048, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322067, Length=198, Percent_Identity=28.7878787878788, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=219, Percent_Identity=26.9406392694064, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=31.9371727748691, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=34.0425531914894, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=31.9148936170213, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24649181, Length=267, Percent_Identity=26.2172284644195, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644339, Length=208, Percent_Identity=31.7307692307692, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28571526, Length=185, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355631, Length=205, Percent_Identity=28.780487804878, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24580925, Length=190, Percent_Identity=30.5263157894737, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364892, Length=216, Percent_Identity=26.8518518518519, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640442, Length=189, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641388, Length=193, Percent_Identity=32.6424870466321, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17737361, Length=198, Percent_Identity=31.3131313131313, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355319, Length=185, Percent_Identity=25.9459459459459, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356301, Length=188, Percent_Identity=28.1914893617021, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27292; Mature: 27161

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLKVFITGASSGLGLAMAEEYARQGAVLALVARRTDVLDAFARRFPKLSVSVYRADV
CCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEECCC
RDADALAAAAASFIAAHGCPDVVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEP
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCC
FVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIKYLEALRVELRPAGVAVVTIA
HHCCHHHHCCCCEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
PGYIRTPMTAHNPYPMPFLMDADRFAAQAARAIARKHAFRVIPWQMGVVAKVLHVLPRWL
CCHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHHH
YDRLFERAPRKPRAGAH
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTPLKVFITGASSGLGLAMAEEYARQGAVLALVARRTDVLDAFARRFPKLSVSVYRADV
CCCEEEEEEECCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEECCC
RDADALAAAAASFIAAHGCPDVVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEP
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCC
FVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIKYLEALRVELRPAGVAVVTIA
HHCCHHHHCCCCEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
PGYIRTPMTAHNPYPMPFLMDADRFAAQAARAIARKHAFRVIPWQMGVVAKVLHVLPRWL
CCHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHHH
YDRLFERAPRKPRAGAH
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]