| Definition | Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010084 |
| Length | 3,448,466 |
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The map label for this gene is aceK [H]
Identifier: 161523559
GI number: 161523559
Start: 416180
End: 417997
Strand: Reverse
Name: aceK [H]
Synonym: Bmul_0379
Alternate gene names: 161523559
Gene position: 417997-416180 (Counterclockwise)
Preceding gene: 161523561
Following gene: 161523558
Centisome position: 12.12
GC content: 63.31
Gene sequence:
>1818_bases ATGAATCACTTCCCCAAACTGCTGTCGTCGCAGATCGGCTTCGACGTCGCACAGTCGATGCTCGAGTACTTCGACCGCCA CTACCGGATCTTCCGCGAAGCGGCCGTCGAAGCGAAGGCGCTGTTCGAGCGCGCCGACTGGCATGGGCTGCAGCGGCTGG CGCGCGAGCGGATCACGTCGTACGACGAGCGCGTGCAGGAATGCGTCGAGGTGCTGCAGGACGAATACGACGCGGAGAGC ATCGACGACGAAGTCTGGCAGCAGATCAAGCTCCATTACATCGGCCTGCTGACGTCGCACCGCCAGCCCGAGTGCGCGGA AACCTTCTTCAATTCGGTGTGCTGCAAGATCCTGCACCGGTCGTATTTCAACAACGACTTCATCTTCGTGCGCCCGGCGA TCTCGACCGAATACCTCGAGAACGACGAGCCGGCCGCGAAACCGACGTATCGCGCGTACTATCCGGGCACCGACGGGCTC GCGGTCACGCTCGAGCGGATCGTCACGAACTTCCAGCTCGAGCCGCCGTTCGAGGATCTCGCGCGCGACATCGCGTGCGT GATGCAGGCGATCCACGACGAATTCGGCCGTTTCGACGAAGCGCCGAATTTCCAGATCCACGTGCTGTCGTCGCTGTTCT TCCGCAACAAGAGCGCGTACATCGTCGGCCGCATCATCAACGCCGATCGCGTGCTGCCGTTCGCGGTGCCGATCCGCCAC GTGCGGCCCGGCCTGCTCGCGCTGGACACGGTGCTGCTGCGCCGCGACCTGCTGCAGATCATCTTCAGCTTCTCGCACTC GTACTTCCTCGTCGACATGGACGTGCCGTCCGCGTACGTCGATTTCCTCTGCACGATCATGCCCGGCAAGCCGAAGGCCG AGATCTACACGTCGGTCGGGCTGCAGAAGCAGGGCAAGAACCTGTTCTACCGCGACCTGCTGCATCACCTGTCGCATTCG AGCGACCGCTTCATCGTCGCGCCGGGGATCAAGGGCCTCGTGATGCTCGTGTTCACGCTGCCGTCGTTCCCGTACGTGTT CAAGATCATCAAGGATCACTTCCCGCCGCCGAAGGAAACGACGCGCCGGCAGATCATGGAGAAGTATCTGCTCGTGAAGC GCCACGACCGGCTCGGACGCATGGCCGACACGCTCGAATATTCGAGCGTCGCGCTGCCGCTCGCGCGGCTCGATCACGCG CTCGTGCGCGAACTCGAGAAGGAAGTCCCGTCGCTGCTCGAGTACGAGGGCGACAATCTCGTGATCAAGCATCTCTACAT CGAGCGCCGGATGACGCCGCTGAACCTCTATCTGCAGAACGGCACCGACGCGGAAGTCGAGCACGGCGTGAAGGAATACG GCAACGCGGTGAAGGAGTTGATGAAGGCCAACATCTTCCCCGGCGACATGCTGTACAAGAATTTCGGCGTCACGCGCCAC GGCCGCGTCGTGTTCTACGACTACGACGAGATCGAGTATCTGACGGACTGCAACGTGCGCCGCGTGCCGCCGCCGCGCAA CGAAGAAGACGAGCTGTCCGGCGAACCGTGGTATACCGTCGGCCCGCACGACATCTTTCCCGAGACCTACGGTCCGTTCC TGCTCGGCGATCCGCGCGTGCGCGCCGCGTTCCTCAAGCATCACGCGGACTTCTTCGATCCGGCGCTGTGGCAGGCGAGC AAGGACAAGCTGCTGCAGGGCGAACTGCCCGATTTCTTTCCGTACGATGCGTCGCTGCGCTTCTGCGTACGCTATCCGGA GCGCTTTCGCGCGACGGACGAGCGTGCGCCGGCGCGCGGCGCGCAGCGTGCGGCCTGA
Upstream 100 bases:
>100_bases CCGGCGTGCCGCGCCGGATGTCATGGAAACGGCGACTTGGGCGCTAAAATGGCGCGTGGAGCGAACAGTCCCCCGCCCCT TTTGAGCGAGCCTGCACGCA
Downstream 100 bases:
>100_bases TGTGTTTCACCCGAACCCGATATCGAACGATTCACGATGACGGACACCACCACGATGAATACCCAAGATCACCCGCTTTC CCACCTGTTCGACAACAACG
Product: bifunctional isocitrate dehydrogenase kinase/phosphatase protein
Products: NA
Alternate protein names: IDH kinase/phosphatase; IDHK/P [H]
Number of amino acids: Translated: 605; Mature: 605
Protein sequence:
>605_residues MNHFPKLLSSQIGFDVAQSMLEYFDRHYRIFREAAVEAKALFERADWHGLQRLARERITSYDERVQECVEVLQDEYDAES IDDEVWQQIKLHYIGLLTSHRQPECAETFFNSVCCKILHRSYFNNDFIFVRPAISTEYLENDEPAAKPTYRAYYPGTDGL AVTLERIVTNFQLEPPFEDLARDIACVMQAIHDEFGRFDEAPNFQIHVLSSLFFRNKSAYIVGRIINADRVLPFAVPIRH VRPGLLALDTVLLRRDLLQIIFSFSHSYFLVDMDVPSAYVDFLCTIMPGKPKAEIYTSVGLQKQGKNLFYRDLLHHLSHS SDRFIVAPGIKGLVMLVFTLPSFPYVFKIIKDHFPPPKETTRRQIMEKYLLVKRHDRLGRMADTLEYSSVALPLARLDHA LVRELEKEVPSLLEYEGDNLVIKHLYIERRMTPLNLYLQNGTDAEVEHGVKEYGNAVKELMKANIFPGDMLYKNFGVTRH GRVVFYDYDEIEYLTDCNVRRVPPPRNEEDELSGEPWYTVGPHDIFPETYGPFLLGDPRVRAAFLKHHADFFDPALWQAS KDKLLQGELPDFFPYDASLRFCVRYPERFRATDERAPARGAQRAA
Sequences:
>Translated_605_residues MNHFPKLLSSQIGFDVAQSMLEYFDRHYRIFREAAVEAKALFERADWHGLQRLARERITSYDERVQECVEVLQDEYDAES IDDEVWQQIKLHYIGLLTSHRQPECAETFFNSVCCKILHRSYFNNDFIFVRPAISTEYLENDEPAAKPTYRAYYPGTDGL AVTLERIVTNFQLEPPFEDLARDIACVMQAIHDEFGRFDEAPNFQIHVLSSLFFRNKSAYIVGRIINADRVLPFAVPIRH VRPGLLALDTVLLRRDLLQIIFSFSHSYFLVDMDVPSAYVDFLCTIMPGKPKAEIYTSVGLQKQGKNLFYRDLLHHLSHS SDRFIVAPGIKGLVMLVFTLPSFPYVFKIIKDHFPPPKETTRRQIMEKYLLVKRHDRLGRMADTLEYSSVALPLARLDHA LVRELEKEVPSLLEYEGDNLVIKHLYIERRMTPLNLYLQNGTDAEVEHGVKEYGNAVKELMKANIFPGDMLYKNFGVTRH GRVVFYDYDEIEYLTDCNVRRVPPPRNEEDELSGEPWYTVGPHDIFPETYGPFLLGDPRVRAAFLKHHADFFDPALWQAS KDKLLQGELPDFFPYDASLRFCVRYPERFRATDERAPARGAQRAA >Mature_605_residues MNHFPKLLSSQIGFDVAQSMLEYFDRHYRIFREAAVEAKALFERADWHGLQRLARERITSYDERVQECVEVLQDEYDAES IDDEVWQQIKLHYIGLLTSHRQPECAETFFNSVCCKILHRSYFNNDFIFVRPAISTEYLENDEPAAKPTYRAYYPGTDGL AVTLERIVTNFQLEPPFEDLARDIACVMQAIHDEFGRFDEAPNFQIHVLSSLFFRNKSAYIVGRIINADRVLPFAVPIRH VRPGLLALDTVLLRRDLLQIIFSFSHSYFLVDMDVPSAYVDFLCTIMPGKPKAEIYTSVGLQKQGKNLFYRDLLHHLSHS SDRFIVAPGIKGLVMLVFTLPSFPYVFKIIKDHFPPPKETTRRQIMEKYLLVKRHDRLGRMADTLEYSSVALPLARLDHA LVRELEKEVPSLLEYEGDNLVIKHLYIERRMTPLNLYLQNGTDAEVEHGVKEYGNAVKELMKANIFPGDMLYKNFGVTRH GRVVFYDYDEIEYLTDCNVRRVPPPRNEEDELSGEPWYTVGPHDIFPETYGPFLLGDPRVRAAFLKHHADFFDPALWQAS KDKLLQGELPDFFPYDASLRFCVRYPERFRATDERAPARGAQRAA
Specific function: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source
COG id: COG4579
COG function: function code T; Isocitrate dehydrogenase kinase/phosphatase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the AceK family [H]
Homologues:
Organism=Escherichia coli, GI1790446, Length=572, Percent_Identity=41.0839160839161, Blast_Score=451, Evalue=1e-128,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR010452 - ProDom: PD043552 [H]
Pfam domain/function: PF06315 AceK [H]
EC number: =2.7.11.5 [H]
Molecular weight: Translated: 70257; Mature: 70257
Theoretical pI: Translated: 6.21; Mature: 6.21
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNHFPKLLSSQIGFDVAQSMLEYFDRHYRIFREAAVEAKALFERADWHGLQRLARERITS CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YDERVQECVEVLQDEYDAESIDDEVWQQIKLHYIGLLTSHRQPECAETFFNSVCCKILHR HHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH SYFNNDFIFVRPAISTEYLENDEPAAKPTYRAYYPGTDGLAVTLERIVTNFQLEPPFEDL HHCCCCEEEEECCCCHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHH ARDIACVMQAIHDEFGRFDEAPNFQIHVLSSLFFRNKSAYIVGRIINADRVLPFAVPIRH HHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHH VRPGLLALDTVLLRRDLLQIIFSFSHSYFLVDMDVPSAYVDFLCTIMPGKPKAEIYTSVG HCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHCC LQKQGKNLFYRDLLHHLSHSSDRFIVAPGIKGLVMLVFTLPSFPYVFKIIKDHFPPPKET CHHCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHH TRRQIMEKYLLVKRHDRLGRMADTLEYSSVALPLARLDHALVRELEKEVPSLLEYEGDNL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE VIKHLYIERRMTPLNLYLQNGTDAEVEHGVKEYGNAVKELMKANIFPGDMLYKNFGVTRH EEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC GRVVFYDYDEIEYLTDCNVRRVPPPRNEEDELSGEPWYTVGPHDIFPETYGPFLLGDPRV CEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCHHCCCCCCCCCEECCHHH RAAFLKHHADFFDPALWQASKDKLLQGELPDFFPYDASLRFCVRYPERFRATDERAPARG HHHHHHHHHHHCCHHHHHCCHHHHHCCCCCCCCCCCCCHHHEECCCHHHCCCCCCCCCCC AQRAA CCCCC >Mature Secondary Structure MNHFPKLLSSQIGFDVAQSMLEYFDRHYRIFREAAVEAKALFERADWHGLQRLARERITS CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YDERVQECVEVLQDEYDAESIDDEVWQQIKLHYIGLLTSHRQPECAETFFNSVCCKILHR HHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH SYFNNDFIFVRPAISTEYLENDEPAAKPTYRAYYPGTDGLAVTLERIVTNFQLEPPFEDL HHCCCCEEEEECCCCHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHH ARDIACVMQAIHDEFGRFDEAPNFQIHVLSSLFFRNKSAYIVGRIINADRVLPFAVPIRH HHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHH VRPGLLALDTVLLRRDLLQIIFSFSHSYFLVDMDVPSAYVDFLCTIMPGKPKAEIYTSVG HCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHCC LQKQGKNLFYRDLLHHLSHSSDRFIVAPGIKGLVMLVFTLPSFPYVFKIIKDHFPPPKET CHHCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHH TRRQIMEKYLLVKRHDRLGRMADTLEYSSVALPLARLDHALVRELEKEVPSLLEYEGDNL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE VIKHLYIERRMTPLNLYLQNGTDAEVEHGVKEYGNAVKELMKANIFPGDMLYKNFGVTRH EEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC GRVVFYDYDEIEYLTDCNVRRVPPPRNEEDELSGEPWYTVGPHDIFPETYGPFLLGDPRV CEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCHHCCCCCCCCCEECCHHH RAAFLKHHADFFDPALWQASKDKLLQGELPDFFPYDASLRFCVRYPERFRATDERAPARG HHHHHHHHHHHCCHHHHHCCHHHHHCCCCCCCCCCCCCHHHEECCCHHHCCCCCCCCCCC AQRAA CCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA