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The map label for this gene is frvX [H]

Identifier: 160902580

GI number: 160902580

Start: 1200792

End: 1201832

Strand: Direct

Name: frvX [H]

Synonym: Pmob_1119

Alternate gene names: 160902580

Gene position: 1200792-1201832 (Clockwise)

Preceding gene: 160902579

Following gene: 160902581

Centisome position: 55.35

GC content: 36.22

Gene sequence:

>1041_bases
ATGGATACTTCTACTTTACTAAAAAATTTATCCAATACTTTTGGGGTGTCTTCTTTTGAAAATTACACCTTTCCTTTGAT
TGAAGAAGAATTAAAAAACATCTCACCAGATATAAAATTAGAAAAAGTAGGAATAGGTAATTTAGTGGCAACTTATGGAA
ATGAGAGTCCCAAAATTGCCTTTTTCGCACATGTAGACGAAATTGGAATAGTTATATCAAAAATAATCGATGAACACTTC
GCTCGTATTTCTCCCGTTGGTGGAGTCGATCCAAGAACCTTGGTAGGAAAAAGGGTTCTTTTTAAAACGAAAGATGCAGA
AAAAATAGGTGTAATAGGGTTTTTAGCCCCTCACCTTCAAAAAAAGGAAGATAGAGAAAAATCTCCCTCCTTTGATGAGC
TTTTCGTCGATTTTTCAATTTCAGGGGGAACAAGCAATATCAACGTTGGTGATATGGGCGTTATACAAGTCCAGGCTGTT
GAACTTGAAAATGGAAAGATATCAAATAAATCTTTAGACAACAGAGTAGGTGCTGCGGTACTAATTAAGTCTTTGGAGTA
CCTACAAAATCTTAAATTTGAAGGACAATTGACTTTGTCTTTTAACAAAGGTGAGGAAGTGGGATTAGTTGGAGCACAAG
GTAGCGCTCACCACCGAAAACCAGATTTTGCCATAGTAGTTGATGTAACTTTTGGCGAAAAACTACCAGAAAACTTTGAG
CCTATCAAGCTTGGTGAAGGACCAGTTATAGGTATAGGTACCACCGTTACCAGAAGTATTTTCGAAGAACTAACAAAAAC
TGCAAAAAGTAACAATATCAAATACCAATTAGAAACTTTTACTAGAGGCAGTGGCACCGAAGCGGATGTAGTTCAAATAT
CTTCTACCGGAGTAAAAACAGGTGTTGTTTCAGTTCCAATCCTTAACATGCATTCTCCCAACGAGGTTGTAGATGTAAAA
GATGTGGAAGAAAGCGCAAAATTATTATCTTTCTTTGCTTTAAACACCAGCTTAACTTGGAAAGGAAGTAGAAATTTATG
A

Upstream 100 bases:

>100_bases
GAACTGTAAAAATATAGTGGAGCAAAGAGATATTAAATCAATTTTTTTTAATCTTTAAAATACTATTTATCCTGTGTCAA
AACCAAAAAGGAGGTCACGA

Downstream 100 bases:

>100_bases
GGAAGTATTTAAAAGACTTAACTAATCTTGCCGGTATATCTTCAAGAGAAGAAAAAATAAGAGAGTACATCAAATCAAAT
GTTGCCAACAAGGTCGATGA

Product: peptidase M42 family protein

Products: D-glucose; GDP

Alternate protein names: TET; TET aminopeptidase; Leucyl aminopeptidase; PhTET2 [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MDTSTLLKNLSNTFGVSSFENYTFPLIEEELKNISPDIKLEKVGIGNLVATYGNESPKIAFFAHVDEIGIVISKIIDEHF
ARISPVGGVDPRTLVGKRVLFKTKDAEKIGVIGFLAPHLQKKEDREKSPSFDELFVDFSISGGTSNINVGDMGVIQVQAV
ELENGKISNKSLDNRVGAAVLIKSLEYLQNLKFEGQLTLSFNKGEEVGLVGAQGSAHHRKPDFAIVVDVTFGEKLPENFE
PIKLGEGPVIGIGTTVTRSIFEELTKTAKSNNIKYQLETFTRGSGTEADVVQISSTGVKTGVVSVPILNMHSPNEVVDVK
DVEESAKLLSFFALNTSLTWKGSRNL

Sequences:

>Translated_346_residues
MDTSTLLKNLSNTFGVSSFENYTFPLIEEELKNISPDIKLEKVGIGNLVATYGNESPKIAFFAHVDEIGIVISKIIDEHF
ARISPVGGVDPRTLVGKRVLFKTKDAEKIGVIGFLAPHLQKKEDREKSPSFDELFVDFSISGGTSNINVGDMGVIQVQAV
ELENGKISNKSLDNRVGAAVLIKSLEYLQNLKFEGQLTLSFNKGEEVGLVGAQGSAHHRKPDFAIVVDVTFGEKLPENFE
PIKLGEGPVIGIGTTVTRSIFEELTKTAKSNNIKYQLETFTRGSGTEADVVQISSTGVKTGVVSVPILNMHSPNEVVDVK
DVEESAKLLSFFALNTSLTWKGSRNL
>Mature_346_residues
MDTSTLLKNLSNTFGVSSFENYTFPLIEEELKNISPDIKLEKVGIGNLVATYGNESPKIAFFAHVDEIGIVISKIIDEHF
ARISPVGGVDPRTLVGKRVLFKTKDAEKIGVIGFLAPHLQKKEDREKSPSFDELFVDFSISGGTSNINVGDMGVIQVQAV
ELENGKISNKSLDNRVGAAVLIKSLEYLQNLKFEGQLTLSFNKGEEVGLVGAQGSAHHRKPDFAIVVDVTFGEKLPENFE
PIKLGEGPVIGIGTTVTRSIFEELTKTAKSNNIKYQLETFTRGSGTEADVVQISSTGVKTGVVSVPILNMHSPNEVVDVK
DVEESAKLLSFFALNTSLTWKGSRNL

Specific function: Functions as an aminopeptidase, with a clear preference for leucine as the N-terminal amino acid. However, can also cleave moderately long polypeptide substrates of various compositions in a fairly unspecific manner. Has neither carboxypeptidase nor endop

COG id: COG1363

COG function: function code G; Cellulase M and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M42 family [H]

Homologues:

Organism=Escherichia coli, GI1790332, Length=348, Percent_Identity=28.735632183908, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082417, Length=344, Percent_Identity=26.453488372093, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788727, Length=354, Percent_Identity=26.271186440678, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008007 [H]

Pfam domain/function: PF05343 Peptidase_M42 [H]

EC number: 3.2.1.4

Molecular weight: Translated: 37643; Mature: 37643

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSTLLKNLSNTFGVSSFENYTFPLIEEELKNISPDIKLEKVGIGNLVATYGNESPKIA
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCEE
FFAHVDEIGIVISKIIDEHFARISPVGGVDPRTLVGKRVLFKTKDAEKIGVIGFLAPHLQ
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEEECCCCCCEEEEEHHHHHHH
KKEDREKSPSFDELFVDFSISGGTSNINVGDMGVIQVQAVELENGKISNKSLDNRVGAAV
CHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
LIKSLEYLQNLKFEGQLTLSFNKGEEVGLVGAQGSAHHRKPDFAIVVDVTFGEKLPENFE
HHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCC
PIKLGEGPVIGIGTTVTRSIFEELTKTAKSNNIKYQLETFTRGSGTEADVVQISSTGVKT
CEEECCCCEEEECHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEEECCCCCC
GVVSVPILNMHSPNEVVDVKDVEESAKLLSFFALNTSLTWKGSRNL
CEEEEEEEECCCCCCEEEHHHHHHHHHHHHHEEECCEEEECCCCCC
>Mature Secondary Structure
MDTSTLLKNLSNTFGVSSFENYTFPLIEEELKNISPDIKLEKVGIGNLVATYGNESPKIA
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCEE
FFAHVDEIGIVISKIIDEHFARISPVGGVDPRTLVGKRVLFKTKDAEKIGVIGFLAPHLQ
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEEECCCCCCEEEEEHHHHHHH
KKEDREKSPSFDELFVDFSISGGTSNINVGDMGVIQVQAVELENGKISNKSLDNRVGAAV
CHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
LIKSLEYLQNLKFEGQLTLSFNKGEEVGLVGAQGSAHHRKPDFAIVVDVTFGEKLPENFE
HHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCC
PIKLGEGPVIGIGTTVTRSIFEELTKTAKSNNIKYQLETFTRGSGTEADVVQISSTGVKT
CEEECCCCEEEECHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEEECCCCCC
GVVSVPILNMHSPNEVVDVKDVEESAKLLSFFALNTSLTWKGSRNL
CEEEEEEEECCCCCCEEEHHHHHHHHHHHHHEEECCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPglucose; H2O

Specific reaction: GDP-glucose + H2O = D-glucose + GDP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]