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The map label for this gene is atoD [H]

Identifier: 160902536

GI number: 160902536

Start: 1150233

End: 1150889

Strand: Direct

Name: atoD [H]

Synonym: Pmob_1075

Alternate gene names: 160902536

Gene position: 1150233-1150889 (Clockwise)

Preceding gene: 160902529

Following gene: 160902537

Centisome position: 53.02

GC content: 37.6

Gene sequence:

>657_bases
TTGAAAATCGTCAGCCCACAAGAAGCAATTTCCTTCATTTCTGAAGGAACTACCTTAATGATAGGGGGGTTTTTGGGCGT
TGGAACACCAGAAACTTTGATAGACGAACTAATAAATAAAAGGAAAAGTAACTTAACAGTTATATGCAACGATACTTCTT
TTGAAGACAAGGGTATCGGTAGATTAATTGCTAGCAAACTCGTAAAAAAAGTGATAACCTCCCATATTGGAACGAACAAA
GAAACTCAAAGACAATGTATAGAAAACGAGTTGGAAGTTGAGTTTGTCCCTCAAGGCACATTAATAGAACAAATTAGAGC
TGGGGGGGCTGGGCTTGGAGGCATATTAACTCCAACCGGGATAGGAACTATAAGAGAAAAAAATAAACAACTCATTGAGA
TAGAGGGGAAAAAATATATTCTTGAAAAAGCTCTTAGAGGAAGAGTAGCGCTTGTTAAATCCAGTAAAGCCGATCATCTT
GGAAATTTACAATGTTCATTCACCGCAAGAAACTTTAACCCGGTTATGGCCCTAGCTTGTGACATCGTTATTGCCGAAGT
AGATGAACTTGTTCCAACAGGTAGTATATGTCCTGATGAAATTCATATTCCTGGAGCTATTGTTGATTACGTTGTTATAA
GGAGTGAAAAAAGATGA

Upstream 100 bases:

>100_bases
ACAAAAATGTAAAAAAAGAGGTAAAATATTACATGTATAAAAAAGTTAAGAAATTTTTTGATAAAAGTATAACAAAAACA
TTACAGAAGGGGTGAGTGAA

Downstream 100 bases:

>100_bases
ATGAAAAAGAAAGGATCGCTAAAAGGGTAGCAAAAGAATTGAAACCAGGAAATATTGTCAACTTAGGAATCGGTTTGCCG
ACTTTGGTATCTAACTTTGT

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKIVSPQEAISFISEGTTLMIGGFLGVGTPETLIDELINKRKSNLTVICNDTSFEDKGIGRLIASKLVKKVITSHIGTNK
ETQRQCIENELEVEFVPQGTLIEQIRAGGAGLGGILTPTGIGTIREKNKQLIEIEGKKYILEKALRGRVALVKSSKADHL
GNLQCSFTARNFNPVMALACDIVIAEVDELVPTGSICPDEIHIPGAIVDYVVIRSEKR

Sequences:

>Translated_218_residues
MKIVSPQEAISFISEGTTLMIGGFLGVGTPETLIDELINKRKSNLTVICNDTSFEDKGIGRLIASKLVKKVITSHIGTNK
ETQRQCIENELEVEFVPQGTLIEQIRAGGAGLGGILTPTGIGTIREKNKQLIEIEGKKYILEKALRGRVALVKSSKADHL
GNLQCSFTARNFNPVMALACDIVIAEVDELVPTGSICPDEIHIPGAIVDYVVIRSEKR
>Mature_218_residues
MKIVSPQEAISFISEGTTLMIGGFLGVGTPETLIDELINKRKSNLTVICNDTSFEDKGIGRLIASKLVKKVITSHIGTNK
ETQRQCIENELEVEFVPQGTLIEQIRAGGAGLGGILTPTGIGTIREKNKQLIEIEGKKYILEKALRGRVALVKSSKADHL
GNLQCSFTARNFNPVMALACDIVIAEVDELVPTGSICPDEIHIPGAIVDYVVIRSEKR

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=230, Percent_Identity=40.8695652173913, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI11545841, Length=235, Percent_Identity=39.1489361702128, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1788551, Length=217, Percent_Identity=51.6129032258064, Blast_Score=243, Evalue=9e-66,
Organism=Escherichia coli, GI1787985, Length=244, Percent_Identity=27.4590163934426, Blast_Score=81, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17531517, Length=229, Percent_Identity=37.117903930131, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24655794, Length=222, Percent_Identity=41.4414414414414, Blast_Score=173, Evalue=8e-44,
Organism=Drosophila melanogaster, GI21358325, Length=222, Percent_Identity=41.4414414414414, Blast_Score=173, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23640; Mature: 23640

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVSPQEAISFISEGTTLMIGGFLGVGTPETLIDELINKRKSNLTVICNDTSFEDKGIG
CCCCCHHHHHHHHHCCCEEEEECEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
RLIASKLVKKVITSHIGTNKETQRQCIENELEVEFVPQGTLIEQIRAGGAGLGGILTPTG
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCCCCCCCCC
IGTIREKNKQLIEIEGKKYILEKALRGRVALVKSSKADHLGNLQCSFTARNFNPVMALAC
CCHHHHCCCEEEEECCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHH
DIVIAEVDELVPTGSICPDEIHIPGAIVDYVVIRSEKR
HHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIVSPQEAISFISEGTTLMIGGFLGVGTPETLIDELINKRKSNLTVICNDTSFEDKGIG
CCCCCHHHHHHHHHCCCEEEEECEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
RLIASKLVKKVITSHIGTNKETQRQCIENELEVEFVPQGTLIEQIRAGGAGLGGILTPTG
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCCCCCCCCC
IGTIREKNKQLIEIEGKKYILEKALRGRVALVKSSKADHLGNLQCSFTARNFNPVMALAC
CCHHHHCCCEEEEECCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHH
DIVIAEVDELVPTGSICPDEIHIPGAIVDYVVIRSEKR
HHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]