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The map label for this gene is pgi [H]

Identifier: 160902527

GI number: 160902527

Start: 1135131

End: 1136504

Strand: Direct

Name: pgi [H]

Synonym: Pmob_1066

Alternate gene names: 160902527

Gene position: 1135131-1136504 (Clockwise)

Preceding gene: 160902526

Following gene: 160902528

Centisome position: 52.32

GC content: 35.74

Gene sequence:

>1374_bases
ATGAATGGTATAAAATTTGATTTTTCAAATGTTTTCCATCCCAATATTGAAAATGGCTTAACGGAAGAAGAAATAAACGA
CCAAGGCAATAGAGTTCAAGATATTGTGGAAACGATAATACAAAACAATCCTGGCTTTTTAAATCTGCCCTTCACAAGGG
TTTACATAGATAGAGTTTTGGATTTAAAAACGTGGATACAAAGTTTTGAAAGTGTAGTAGTTTTAGGCATAGGTGGTTCT
GCATTAGGAAATCAGGCGCTGCAAACAGCCCTTAATCCATTGCATTATAACGCTTTATCTAAAGAAATAAGAAAAACCCC
TAAGATTTTCATCCTTGATAATGTTGACCCCGATTTTATAGCATCAGTTTTGGACCAAATCGATCCAAAGACTACCTTGT
TCAATGTTATTTCAAAATCTGGAACAACAGCAGAAGCCATGGCAAATTATCTGGTTGCAAGAGGAATAATCGAAGGATAC
GGATTAGATCCAAAAAAACACTTCCTATTCACCACCGATCCTGAAAAAGGTATATTAAAGAAAATAGCCGAAGAAGAAGG
AATCAAAACCTTGGATATACCTCCTTCAATTGGCGGTAGATTCAGCGTTTTAACCCCTGTTGGCTTATTATCAGCTTTGG
CAAGTGGAATAGATATAATTGATCTATACAACGGTGCAAAAGAAATGCACAAAAGGGTTACCAATCCAAATATTTGGGAA
AATCCTGCGGCTTTTAACGCCTTAGTGCATTATCTATATTACCAGAAAGGTTACAATATTTCCGTAATGATGTCCTACTC
AAACAAATTGTTTCTACTAGCTGATTGGTACAGACAATTATGGGCAGAAAGCCTTGGAAAAAAATACAATTTAAAAGGTG
AAGTAGTCAACGTTGGGCAAACTCCAATAAAAGCATTAGGCACAACAGACCAACATTCCCAAGTTCAACTATACAACGAA
GGTCCATACGATAAGGTAATCACTTTCATACAACTAGAAAATTTTGAACGAAACATAAAAATCCCTAATATACACTGTGA
CCTTCCCGAGCTATCATATCTGGGAGGTAAAAATCTTTCAGCCCTTTTGAATACAGAATTAGCTGGTACGGAATACGCTT
TAACAGAAAACAATAGACCAAATCTAAAAGTTATTTTCCCTCAGATCAATCCCTTCAATGTGGGACAATTCATATTCGCA
TATGAATTTCAAACAGCAGTAATGGGAAATCTTTTAGATATAAACCCTTATGACCAACCAGGCGTCGAATTAGGTAAAAA
GGTTACTTATGCTTTGATGGGCAGGAAAGGGTACGAAGATTTTAACATCGAAGTAGAAAACAAACTTAAAAACAAAAAAC
AGGTGACGATGTAA

Upstream 100 bases:

>100_bases
TTAACCTATCTAAATCCAAGAGAAAATTTAAAAGATTTGGAAATTGCCAGCTTGATACGATATTGAAAGTTTAATTTAAA
CGTAAGAAGGGGGAAAAAAG

Downstream 100 bases:

>100_bases
AAAATGGTAATAGGAATTACAGGCCCGGCTGGATCTGGAAAAAGCACTATATCAAAGATAATAAAAACAATATACAAAGA
TAAGGCATCCATAATCGATG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MNGIKFDFSNVFHPNIENGLTEEEINDQGNRVQDIVETIIQNNPGFLNLPFTRVYIDRVLDLKTWIQSFESVVVLGIGGS
ALGNQALQTALNPLHYNALSKEIRKTPKIFILDNVDPDFIASVLDQIDPKTTLFNVISKSGTTAEAMANYLVARGIIEGY
GLDPKKHFLFTTDPEKGILKKIAEEEGIKTLDIPPSIGGRFSVLTPVGLLSALASGIDIIDLYNGAKEMHKRVTNPNIWE
NPAAFNALVHYLYYQKGYNISVMMSYSNKLFLLADWYRQLWAESLGKKYNLKGEVVNVGQTPIKALGTTDQHSQVQLYNE
GPYDKVITFIQLENFERNIKIPNIHCDLPELSYLGGKNLSALLNTELAGTEYALTENNRPNLKVIFPQINPFNVGQFIFA
YEFQTAVMGNLLDINPYDQPGVELGKKVTYALMGRKGYEDFNIEVENKLKNKKQVTM

Sequences:

>Translated_457_residues
MNGIKFDFSNVFHPNIENGLTEEEINDQGNRVQDIVETIIQNNPGFLNLPFTRVYIDRVLDLKTWIQSFESVVVLGIGGS
ALGNQALQTALNPLHYNALSKEIRKTPKIFILDNVDPDFIASVLDQIDPKTTLFNVISKSGTTAEAMANYLVARGIIEGY
GLDPKKHFLFTTDPEKGILKKIAEEEGIKTLDIPPSIGGRFSVLTPVGLLSALASGIDIIDLYNGAKEMHKRVTNPNIWE
NPAAFNALVHYLYYQKGYNISVMMSYSNKLFLLADWYRQLWAESLGKKYNLKGEVVNVGQTPIKALGTTDQHSQVQLYNE
GPYDKVITFIQLENFERNIKIPNIHCDLPELSYLGGKNLSALLNTELAGTEYALTENNRPNLKVIFPQINPFNVGQFIFA
YEFQTAVMGNLLDINPYDQPGVELGKKVTYALMGRKGYEDFNIEVENKLKNKKQVTM
>Mature_457_residues
MNGIKFDFSNVFHPNIENGLTEEEINDQGNRVQDIVETIIQNNPGFLNLPFTRVYIDRVLDLKTWIQSFESVVVLGIGGS
ALGNQALQTALNPLHYNALSKEIRKTPKIFILDNVDPDFIASVLDQIDPKTTLFNVISKSGTTAEAMANYLVARGIIEGY
GLDPKKHFLFTTDPEKGILKKIAEEEGIKTLDIPPSIGGRFSVLTPVGLLSALASGIDIIDLYNGAKEMHKRVTNPNIWE
NPAAFNALVHYLYYQKGYNISVMMSYSNKLFLLADWYRQLWAESLGKKYNLKGEVVNVGQTPIKALGTTDQHSQVQLYNE
GPYDKVITFIQLENFERNIKIPNIHCDLPELSYLGGKNLSALLNTELAGTEYALTENNRPNLKVIFPQINPFNVGQFIFA
YEFQTAVMGNLLDINPYDQPGVELGKKVTYALMGRKGYEDFNIEVENKLKNKKQVTM

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=417, Percent_Identity=28.0575539568345, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI296080693, Length=357, Percent_Identity=28.0112044817927, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1790457, Length=390, Percent_Identity=30, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71996708, Length=385, Percent_Identity=27.7922077922078, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71996703, Length=385, Percent_Identity=27.7922077922078, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319673, Length=377, Percent_Identity=28.6472148541114, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24651916, Length=396, Percent_Identity=29.2929292929293, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24651914, Length=396, Percent_Identity=29.2929292929293, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17737445, Length=396, Percent_Identity=29.2929292929293, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 51324; Mature: 51324

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGIKFDFSNVFHPNIENGLTEEEINDQGNRVQDIVETIIQNNPGFLNLPFTRVYIDRVL
CCCCEECCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHH
DLKTWIQSFESVVVLGIGGSALGNQALQTALNPLHYNALSKEIRKTPKIFILDNVDPDFI
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCCCHHHH
ASVLDQIDPKTTLFNVISKSGTTAEAMANYLVARGIIEGYGLDPKKHFLFTTDPEKGILK
HHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHH
KIAEEEGIKTLDIPPSIGGRFSVLTPVGLLSALASGIDIIDLYNGAKEMHKRVTNPNIWE
HHHHHCCCEEEECCCCCCCCEEHHHHHHHHHHHHCCCEEEEHHCCHHHHHHHCCCCCCCC
NPAAFNALVHYLYYQKGYNISVMMSYSNKLFLLADWYRQLWAESLGKKYNLKGEVVNVGQ
CHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCCEEECCC
TPIKALGTTDQHSQVQLYNEGPYDKVITFIQLENFERNIKIPNIHCDLPELSYLGGKNLS
CCHHHCCCCCCCCEEEEECCCCHHHHEEEEEEECCCCCCCCCEEEECCCHHHHCCCCCHH
ALLNTELAGTEYALTENNRPNLKVIFPQINPFNVGQFIFAYEFQTAVMGNLLDINPYDQP
HHHCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHCCEEECCCCCCC
GVELGKKVTYALMGRKGYEDFNIEVENKLKNKKQVTM
CHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCCCCCCC
>Mature Secondary Structure
MNGIKFDFSNVFHPNIENGLTEEEINDQGNRVQDIVETIIQNNPGFLNLPFTRVYIDRVL
CCCCEECCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHH
DLKTWIQSFESVVVLGIGGSALGNQALQTALNPLHYNALSKEIRKTPKIFILDNVDPDFI
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCCCHHHH
ASVLDQIDPKTTLFNVISKSGTTAEAMANYLVARGIIEGYGLDPKKHFLFTTDPEKGILK
HHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHH
KIAEEEGIKTLDIPPSIGGRFSVLTPVGLLSALASGIDIIDLYNGAKEMHKRVTNPNIWE
HHHHHCCCEEEECCCCCCCCEEHHHHHHHHHHHHCCCEEEEHHCCHHHHHHHCCCCCCCC
NPAAFNALVHYLYYQKGYNISVMMSYSNKLFLLADWYRQLWAESLGKKYNLKGEVVNVGQ
CHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCCEEECCC
TPIKALGTTDQHSQVQLYNEGPYDKVITFIQLENFERNIKIPNIHCDLPELSYLGGKNLS
CCHHHCCCCCCCCEEEEECCCCHHHHEEEEEEECCCCCCCCCEEEECCCHHHHCCCCCHH
ALLNTELAGTEYALTENNRPNLKVIFPQINPFNVGQFIFAYEFQTAVMGNLLDINPYDQP
HHHCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHCCEEECCCCCCC
GVELGKKVTYALMGRKGYEDFNIEVENKLKNKKQVTM
CHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]