Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 160902528

GI number: 160902528

Start: 1136508

End: 1137089

Strand: Direct

Name: coaE [H]

Synonym: Pmob_1067

Alternate gene names: 160902528

Gene position: 1136508-1137089 (Clockwise)

Preceding gene: 160902527

Following gene: 160902529

Centisome position: 52.38

GC content: 30.58

Gene sequence:

>582_bases
ATGGTAATAGGAATTACAGGCCCGGCTGGATCTGGAAAAAGCACTATATCAAAGATAATAAAAACAATATACAAAGATAA
GGCATCCATAATCGATGTGGATAGGTTAGGACACGAGGTCTTAACCTATTTTTTTATCAAAGAGAAATTGAAAGAAAATT
TTGGAGAAGAAATATTCGATGATGATAACAATATTTCTAGATCAAAACTTGGCGAAATAGTTTTTTCAAATCAAGAAAAG
TTAGAATTATTGAATCAGATAGTCCATCCAGAAATTCTTAATAAAACTGAACAAATACTGAAAGAAATTTCAAATAAAAA
TGATATAATAATCATAGATGCAGCTTTGCTTTTCAAAATAGGATTGGACAAATTATGCGATAAAATTATCTACGTAGATG
CCCCAGAAGAATTACGTATTGAAAGGCTGTCAGAAAAACGTGGTATCCCCTTGGAGAAGGCAAAAAACATCGTCAAATCC
CAAGAACACATAAACTCTAAGCGTTGTGATTTCAAAATATTGAATATTGGTAATTTTGACCAATTGTACAAAGAAACAGA
AAAAATTATCCAAAACTTATGA

Upstream 100 bases:

>100_bases
AAAGGTTACTTATGCTTTGATGGGCAGGAAAGGGTACGAAGATTTTAACATCGAAGTAGAAAACAAACTTAAAAACAAAA
AACAGGTGACGATGTAAAAA

Downstream 100 bases:

>100_bases
GGAGGTGTTCGGAATGAAGAAAGTTGTTTCTATTCTTTTCACGGTTTTACTTGTTTCTTTTGCTTTTTCTCAAGTCGAGA
TAGAGTTTTGGCATGGCATG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MVIGITGPAGSGKSTISKIIKTIYKDKASIIDVDRLGHEVLTYFFIKEKLKENFGEEIFDDDNNISRSKLGEIVFSNQEK
LELLNQIVHPEILNKTEQILKEISNKNDIIIIDAALLFKIGLDKLCDKIIYVDAPEELRIERLSEKRGIPLEKAKNIVKS
QEHINSKRCDFKILNIGNFDQLYKETEKIIQNL

Sequences:

>Translated_193_residues
MVIGITGPAGSGKSTISKIIKTIYKDKASIIDVDRLGHEVLTYFFIKEKLKENFGEEIFDDDNNISRSKLGEIVFSNQEK
LELLNQIVHPEILNKTEQILKEISNKNDIIIIDAALLFKIGLDKLCDKIIYVDAPEELRIERLSEKRGIPLEKAKNIVKS
QEHINSKRCDFKILNIGNFDQLYKETEKIIQNL
>Mature_193_residues
MVIGITGPAGSGKSTISKIIKTIYKDKASIIDVDRLGHEVLTYFFIKEKLKENFGEEIFDDDNNISRSKLGEIVFSNQEK
LELLNQIVHPEILNKTEQILKEISNKNDIIIIDAALLFKIGLDKLCDKIIYVDAPEELRIERLSEKRGIPLEKAKNIVKS
QEHINSKRCDFKILNIGNFDQLYKETEKIIQNL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI110227607, Length=162, Percent_Identity=32.0987654320988, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI110227605, Length=162, Percent_Identity=32.0987654320988, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI110227603, Length=162, Percent_Identity=32.0987654320988, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI110227601, Length=162, Percent_Identity=32.0987654320988, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI205277394, Length=166, Percent_Identity=31.9277108433735, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI191252797, Length=169, Percent_Identity=26.0355029585799, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI191252795, Length=169, Percent_Identity=26.0355029585799, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554944, Length=203, Percent_Identity=32.512315270936, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25143409, Length=198, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=209, Percent_Identity=28.7081339712919, Blast_Score=82, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24658602, Length=168, Percent_Identity=29.1666666666667, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644728, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22114; Mature: 22114

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIGITGPAGSGKSTISKIIKTIYKDKASIIDVDRLGHEVLTYFFIKEKLKENFGEEIFD
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHC
DDNNISRSKLGEIVFSNQEKLELLNQIVHPEILNKTEQILKEISNKNDIIIIDAALLFKI
CCCCCCHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
GLDKLCDKIIYVDAPEELRIERLSEKRGIPLEKAKNIVKSQEHINSKRCDFKILNIGNFD
HHHHHHHHHEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHH
QLYKETEKIIQNL
HHHHHHHHHHHCC
>Mature Secondary Structure
MVIGITGPAGSGKSTISKIIKTIYKDKASIIDVDRLGHEVLTYFFIKEKLKENFGEEIFD
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHC
DDNNISRSKLGEIVFSNQEKLELLNQIVHPEILNKTEQILKEISNKNDIIIIDAALLFKI
CCCCCCHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
GLDKLCDKIIYVDAPEELRIERLSEKRGIPLEKAKNIVKSQEHINSKRCDFKILNIGNFD
HHHHHHHHHEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHH
QLYKETEKIIQNL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]