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The map label for this gene is hppA [H]

Identifier: 160902456

GI number: 160902456

Start: 1055739

End: 1057721

Strand: Direct

Name: hppA [H]

Synonym: Pmob_0992

Alternate gene names: 160902456

Gene position: 1055739-1057721 (Clockwise)

Preceding gene: 160902455

Following gene: 160902457

Centisome position: 48.66

GC content: 38.02

Gene sequence:

>1983_bases
ATGGGTGCTATTTCTCAAATCATATCGGTTATATCTGGGTTTATCGGATTAATTTTTACCGTTTTTTTGGTGTTCAATAT
TTTAGAAAAATCCCCTGGGAATGAAAAAATGCAGAAACTTTCAAAAATTATTCAAGTGGGAGCTCGCTCTTTTTTATTCT
CTGAATATAGGATCCTTTTTGTTGTTATATTTTTATTCGCAGCTTTTCTGTGGCTTGTAAGTTCTTATCAAATGGCTTTG
TCTTTTATTTTAGGATCAGTATTTTCTGTTTTATCAGGTTTTCTAGGGATGTCAATAGCCACCAGAGCCAATGCCAGAAC
AACCAATGCAGCGATAAACAATTTAAAAGACGCATTGGCTGTGTCTTTTAATGGCGGAGCGGTTATGGGTATGATTGTTA
CTTCTTTAGGATTAATGGGATTGGGAGGTATATTTTTTCTTGGCAAAGGAAATACTGAACTAATGAGTGGTTATGCTATG
GGAGCATCTTTTGTGGCACTTTTTGCAAGAGTGGGAGGGGGCATTTTCACAAAAGCCGCCGATGTAGGAGCTGATCTAGT
TGGTAAGGTTGAAGCAAATATTCCAGAAGATGATCCAAGAAATCCGGCAGTTATCGCTGACAACGTCGGAGATAATGTGG
GAGATGTTGCAGGTATGGGAGCTGATCTGTATGAATCCTACGTTGGTTCTATTTTTTCTGCCTCAGTCTTAGGAAGTATC
GTTTTTTCTGCTAAGGGAGCACTTTTCCCGTTTTTTGTTGCTTCATCAGGTTTGATATTATCAATTTTTGGTATTATTTT
TGTTAATTACTACATCAAAAAAGCAAAGGAAGTTGAGCCTGAAAAGGTCCTACACTTTGGTACATATATGACGACATTTC
TTCAATCGATAGTTGTCTTTTTCTTATCTAAAATTGTATTCGGAGATTTTTCTGGCGGTTTAATTGTTATTTTAGGTATG
GTAGTTGGAATTCTTATAGGGGTTTCCACTGAATACTACACTGCAAAAAAACCTGTAATAGAGCTAGCTAAAAGCGCTCC
ATCAGGTTCGGCTCCGTTGATTATCAATGGTCTTGCCCTAGGGATGGAATCAACGCTTATCCCTATTCTTTTAATAGGAG
CAGCTATTGTAATTTCATTCTACGTTTACGGTCTTTTTGGAATAGCTATTGCTGCTGTTGGAATGCTTTCAACACTGGGT
ATGAGTTTATCAATCGATGCATACGGTCCTATCGCTGATAATGCAGGTGGAATTGCAGAAATGGCTCATTTAGAACCATA
CGTTCGAGAAAGAACGGACAAGTTGGATGCTGTTGGAAATACCACAGCGGCTATGGGAAAAGGTTTTGCAATAGGATCTG
CTGCATTAACGGCATTGGCTTTGTTCGCTTCTTATTTGCAAGTAACAAATATTTCAGTAGTTGATTTGAATGATGCAAAT
GTGTTCACAGCAATGTTAATCGGTGCCATGCTTCCATTTCTGTTTTCCTCTTTGGTAATGAAAGCAGTTGGTAACGCTGC
AAATCTTATGGTTGAAGAAGTAAGAAGGCAATTTAAAGAAATTGTTGGATTAATGGAAGGAAAAGCTGATCCAGACTACG
GTAAGTGTGTAAAGATCGCTACCGATGGTGCTTTGAAATATATGATACTTCCTTCTTTAATCGCTGTAATAGCTCCAATA
ATTATTTATCTCTTGTTAGGCAAGCAAGCTGTTGCTGGAATGTTAGCTGGAACAACAGGCTCAGGCGTTATGTTAGCGAT
ATTCATGGCTAACTCTGGAGGTGCCTGGGATAACGCTAAGAAGTTAATAGAAACAGGAAAATATGGTGGAAAAGGGTCTT
TGGCTCACAAGGCTTCTGTTGTAGGAGATACTGTGGGGGATCCTTTAAAAGATACAGCAGGACCTTCCATAAATATTTTA
ATAAAACTTATGTCCATAGTTTCTATAGTGATTATTCCTGTCTTAATCAGAATTTTTGAGTGA

Upstream 100 bases:

>100_bases
TATTAGGCATAAGGTATCTTAATCTACCTCATCAGTATTTTTTTATCTATCACTCAAAAACATATGGTATAATTAATTAA
ATTATCAAAGGAGGAAAAGT

Downstream 100 bases:

>100_bases
AACTCTTAGTTAAAATGGTTGGTGTGAATACCATTTTTCCTTCTGGGTAGGAAACGGGTTACAGGACGGAGCCTTGTTTG
CGTCACTGTGCAAACCATGT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MGAISQIISVISGFIGLIFTVFLVFNILEKSPGNEKMQKLSKIIQVGARSFLFSEYRILFVVIFLFAAFLWLVSSYQMAL
SFILGSVFSVLSGFLGMSIATRANARTTNAAINNLKDALAVSFNGGAVMGMIVTSLGLMGLGGIFFLGKGNTELMSGYAM
GASFVALFARVGGGIFTKAADVGADLVGKVEANIPEDDPRNPAVIADNVGDNVGDVAGMGADLYESYVGSIFSASVLGSI
VFSAKGALFPFFVASSGLILSIFGIIFVNYYIKKAKEVEPEKVLHFGTYMTTFLQSIVVFFLSKIVFGDFSGGLIVILGM
VVGILIGVSTEYYTAKKPVIELAKSAPSGSAPLIINGLALGMESTLIPILLIGAAIVISFYVYGLFGIAIAAVGMLSTLG
MSLSIDAYGPIADNAGGIAEMAHLEPYVRERTDKLDAVGNTTAAMGKGFAIGSAALTALALFASYLQVTNISVVDLNDAN
VFTAMLIGAMLPFLFSSLVMKAVGNAANLMVEEVRRQFKEIVGLMEGKADPDYGKCVKIATDGALKYMILPSLIAVIAPI
IIYLLLGKQAVAGMLAGTTGSGVMLAIFMANSGGAWDNAKKLIETGKYGGKGSLAHKASVVGDTVGDPLKDTAGPSINIL
IKLMSIVSIVIIPVLIRIFE

Sequences:

>Translated_660_residues
MGAISQIISVISGFIGLIFTVFLVFNILEKSPGNEKMQKLSKIIQVGARSFLFSEYRILFVVIFLFAAFLWLVSSYQMAL
SFILGSVFSVLSGFLGMSIATRANARTTNAAINNLKDALAVSFNGGAVMGMIVTSLGLMGLGGIFFLGKGNTELMSGYAM
GASFVALFARVGGGIFTKAADVGADLVGKVEANIPEDDPRNPAVIADNVGDNVGDVAGMGADLYESYVGSIFSASVLGSI
VFSAKGALFPFFVASSGLILSIFGIIFVNYYIKKAKEVEPEKVLHFGTYMTTFLQSIVVFFLSKIVFGDFSGGLIVILGM
VVGILIGVSTEYYTAKKPVIELAKSAPSGSAPLIINGLALGMESTLIPILLIGAAIVISFYVYGLFGIAIAAVGMLSTLG
MSLSIDAYGPIADNAGGIAEMAHLEPYVRERTDKLDAVGNTTAAMGKGFAIGSAALTALALFASYLQVTNISVVDLNDAN
VFTAMLIGAMLPFLFSSLVMKAVGNAANLMVEEVRRQFKEIVGLMEGKADPDYGKCVKIATDGALKYMILPSLIAVIAPI
IIYLLLGKQAVAGMLAGTTGSGVMLAIFMANSGGAWDNAKKLIETGKYGGKGSLAHKASVVGDTVGDPLKDTAGPSINIL
IKLMSIVSIVIIPVLIRIFE
>Mature_659_residues
GAISQIISVISGFIGLIFTVFLVFNILEKSPGNEKMQKLSKIIQVGARSFLFSEYRILFVVIFLFAAFLWLVSSYQMALS
FILGSVFSVLSGFLGMSIATRANARTTNAAINNLKDALAVSFNGGAVMGMIVTSLGLMGLGGIFFLGKGNTELMSGYAMG
ASFVALFARVGGGIFTKAADVGADLVGKVEANIPEDDPRNPAVIADNVGDNVGDVAGMGADLYESYVGSIFSASVLGSIV
FSAKGALFPFFVASSGLILSIFGIIFVNYYIKKAKEVEPEKVLHFGTYMTTFLQSIVVFFLSKIVFGDFSGGLIVILGMV
VGILIGVSTEYYTAKKPVIELAKSAPSGSAPLIINGLALGMESTLIPILLIGAAIVISFYVYGLFGIAIAAVGMLSTLGM
SLSIDAYGPIADNAGGIAEMAHLEPYVRERTDKLDAVGNTTAAMGKGFAIGSAALTALALFASYLQVTNISVVDLNDANV
FTAMLIGAMLPFLFSSLVMKAVGNAANLMVEEVRRQFKEIVGLMEGKADPDYGKCVKIATDGALKYMILPSLIAVIAPII
IYLLLGKQAVAGMLAGTTGSGVMLAIFMANSGGAWDNAKKLIETGKYGGKGSLAHKASVVGDTVGDPLKDTAGPSINILI
KLMSIVSIVIIPVLIRIFE

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 69105; Mature: 68973

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAISQIISVISGFIGLIFTVFLVFNILEKSPGNEKMQKLSKIIQVGARSFLFSEYRILF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVIFLFAAFLWLVSSYQMALSFILGSVFSVLSGFLGMSIATRANARTTNAAINNLKDALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHE
VSFNGGAVMGMIVTSLGLMGLGGIFFLGKGNTELMSGYAMGASFVALFARVGGGIFTKAA
EECCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
DVGADLVGKVEANIPEDDPRNPAVIADNVGDNVGDVAGMGADLYESYVGSIFSASVLGSI
HHCHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VFSAKGALFPFFVASSGLILSIFGIIFVNYYIKKAKEVEPEKVLHFGTYMTTFLQSIVVF
HHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FLSKIVFGDFSGGLIVILGMVVGILIGVSTEYYTAKKPVIELAKSAPSGSAPLIINGLAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHCCCCCCCCEEEEHHHH
GMESTLIPILLIGAAIVISFYVYGLFGIAIAAVGMLSTLGMSLSIDAYGPIADNAGGIAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHH
MAHLEPYVRERTDKLDAVGNTTAAMGKGFAIGSAALTALALFASYLQVTNISVVDLNDAN
HHHHCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCH
VFTAMLIGAMLPFLFSSLVMKAVGNAANLMVEEVRRQFKEIVGLMEGKADPDYGKCVKIA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
TDGALKYMILPSLIAVIAPIIIYLLLGKQAVAGMLAGTTGSGVMLAIFMANSGGAWDNAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHH
KLIETGKYGGKGSLAHKASVVGDTVGDPLKDTAGPSINILIKLMSIVSIVIIPVLIRIFE
HHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GAISQIISVISGFIGLIFTVFLVFNILEKSPGNEKMQKLSKIIQVGARSFLFSEYRILF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVIFLFAAFLWLVSSYQMALSFILGSVFSVLSGFLGMSIATRANARTTNAAINNLKDALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHE
VSFNGGAVMGMIVTSLGLMGLGGIFFLGKGNTELMSGYAMGASFVALFARVGGGIFTKAA
EECCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
DVGADLVGKVEANIPEDDPRNPAVIADNVGDNVGDVAGMGADLYESYVGSIFSASVLGSI
HHCHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VFSAKGALFPFFVASSGLILSIFGIIFVNYYIKKAKEVEPEKVLHFGTYMTTFLQSIVVF
HHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FLSKIVFGDFSGGLIVILGMVVGILIGVSTEYYTAKKPVIELAKSAPSGSAPLIINGLAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHCCCCCCCCEEEEHHHH
GMESTLIPILLIGAAIVISFYVYGLFGIAIAAVGMLSTLGMSLSIDAYGPIADNAGGIAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHH
MAHLEPYVRERTDKLDAVGNTTAAMGKGFAIGSAALTALALFASYLQVTNISVVDLNDAN
HHHHCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCH
VFTAMLIGAMLPFLFSSLVMKAVGNAANLMVEEVRRQFKEIVGLMEGKADPDYGKCVKIA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
TDGALKYMILPSLIAVIAPIIIYLLLGKQAVAGMLAGTTGSGVMLAIFMANSGGAWDNAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHH
KLIETGKYGGKGSLAHKASVVGDTVGDPLKDTAGPSINILIKLMSIVSIVIIPVLIRIFE
HHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]