Click here to switch to the map view.

The map label for this gene is ackA [H]

Identifier: 160902120

GI number: 160902120

Start: 697284

End: 698489

Strand: Direct

Name: ackA [H]

Synonym: Pmob_0647

Alternate gene names: 160902120

Gene position: 697284-698489 (Clockwise)

Preceding gene: 160902119

Following gene: 160902122

Centisome position: 32.14

GC content: 35.9

Gene sequence:

>1206_bases
ATGAAAATACTAGTGATCAACTCCGGAAGTTCATCCTTAAAATATCAAATATTAGAAATGGAAAACGAAAGTTGTCTGGT
TAAAGGGTTGGTTGAAAGAATAGGGGAACAAGAATCAGATATTGAACAAGAAAACGAAGGAAAAGAGTACAAAAACATAA
CCAAGATAAAAGACCATGAAGAAGCGTTGAAAAAAGCTATGGAATTGATCACTGATCCTGAATATGGATGTTTAAAAGAA
TTAAATGAGATAGATGCGGTTGGGCACAGGGTAGTACATGGAGGAGAAGAGTTTTTCTCTTCCGTACTGATAGATGAAGA
AGTTATTAAAGCTATAGAAGAGAACTCTGATCTTGCTCCTTTACATAACCCTCCCAATTTGATGGGCATAAGAGCAGCTA
AAAAATTATTACCCAACGTACCTCAAGTAGCGGTATTTGATACATCATTTCACCATTCGATGCCAGAGAAAGCGTACATG
TATGGTTTACCTTACGAAGTTTATCAAAAATACAAGATAAGACGTTATGGATTTCATGGGACCAGTCACAGGTACGTATC
TCAAAAAGCCTCTGAGATATTAAAAAAAGATATGAAAGAATTAAAGATGATAACGGCACATTTAGGTAACGGTGCATCTT
TAGCTGCAATCGACAGAGGAAAAGTGATTGATACATCGATGGGCTTCACACCTTTGGAAGGATTGATAATGGGAACAAGA
AGTGGAGATATAGATCCAGGAATAGTTTTTTTCCTTATAAGAAAAGGCTACAGCGTAGACGAAGTGGACGATTTGTTGAA
CAAAAGAAGTGGTGTCTACGGTTTGAGTAAAATGAGCAACGACATGAGAGACATCAGAAAAGGAATAGAAAATGGGGATA
AAAAGGCAAAGTTGGCATACGATGTGTATGTATATCGTTTAGCAAAATACATAGGAAGTTATATAACCGCACTAAAAGGG
TTAGATGTGCTGGTATTCACAGCGGGTGTGGGAGAAAATGACGAACATGTAAGAATGGACGTCTGTGATTACTTAGACTT
CTTTGGAGTTAAAATTGATAAAGAAAAAAATACTTTGTTGAATAGAAAAAACGGAATTATCTCAGCTTCGGATTCTGATG
TTGACATTTTAATAGTAAAAACTGATGAGGAATTAATGATAGCTCAAGATACTAAAAGAATAGTGGAAGAAGTGAACGAG
AAATAG

Upstream 100 bases:

>100_bases
CTTTTAGGTTCTGCTAATAAAGCTTAATTCAAAGTACAGCCATGGCTTCCATGGTTGTACTTTTTTATTTTAACCAAAAA
TATTAACAGGAGGATTTCGA

Downstream 100 bases:

>100_bases
TAATGCCTGTTTAAAGGGCATTACTATTTTTTGCTATAACTTTTTGCCAAATTAAAGTATTCTTTAGCGTGTTCTTTAAT
TTGTTCGAACTCTTCATCAG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKILVINSGSSSLKYQILEMENESCLVKGLVERIGEQESDIEQENEGKEYKNITKIKDHEEALKKAMELITDPEYGCLKE
LNEIDAVGHRVVHGGEEFFSSVLIDEEVIKAIEENSDLAPLHNPPNLMGIRAAKKLLPNVPQVAVFDTSFHHSMPEKAYM
YGLPYEVYQKYKIRRYGFHGTSHRYVSQKASEILKKDMKELKMITAHLGNGASLAAIDRGKVIDTSMGFTPLEGLIMGTR
SGDIDPGIVFFLIRKGYSVDEVDDLLNKRSGVYGLSKMSNDMRDIRKGIENGDKKAKLAYDVYVYRLAKYIGSYITALKG
LDVLVFTAGVGENDEHVRMDVCDYLDFFGVKIDKEKNTLLNRKNGIISASDSDVDILIVKTDEELMIAQDTKRIVEEVNE
K

Sequences:

>Translated_401_residues
MKILVINSGSSSLKYQILEMENESCLVKGLVERIGEQESDIEQENEGKEYKNITKIKDHEEALKKAMELITDPEYGCLKE
LNEIDAVGHRVVHGGEEFFSSVLIDEEVIKAIEENSDLAPLHNPPNLMGIRAAKKLLPNVPQVAVFDTSFHHSMPEKAYM
YGLPYEVYQKYKIRRYGFHGTSHRYVSQKASEILKKDMKELKMITAHLGNGASLAAIDRGKVIDTSMGFTPLEGLIMGTR
SGDIDPGIVFFLIRKGYSVDEVDDLLNKRSGVYGLSKMSNDMRDIRKGIENGDKKAKLAYDVYVYRLAKYIGSYITALKG
LDVLVFTAGVGENDEHVRMDVCDYLDFFGVKIDKEKNTLLNRKNGIISASDSDVDILIVKTDEELMIAQDTKRIVEEVNE
K
>Mature_401_residues
MKILVINSGSSSLKYQILEMENESCLVKGLVERIGEQESDIEQENEGKEYKNITKIKDHEEALKKAMELITDPEYGCLKE
LNEIDAVGHRVVHGGEEFFSSVLIDEEVIKAIEENSDLAPLHNPPNLMGIRAAKKLLPNVPQVAVFDTSFHHSMPEKAYM
YGLPYEVYQKYKIRRYGFHGTSHRYVSQKASEILKKDMKELKMITAHLGNGASLAAIDRGKVIDTSMGFTPLEGLIMGTR
SGDIDPGIVFFLIRKGYSVDEVDDLLNKRSGVYGLSKMSNDMRDIRKGIENGDKKAKLAYDVYVYRLAKYIGSYITALKG
LDVLVFTAGVGENDEHVRMDVCDYLDFFGVKIDKEKNTLLNRKNGIISASDSDVDILIVKTDEELMIAQDTKRIVEEVNE
K

Specific function: Phosphorylates propionate (54%) in addition to acetate (100%). Uses GTP (100%), ITP (163%), UTP (56%), and CTP (21%) as phosphoryl donors in addition to ATP (100%) [H]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=402, Percent_Identity=45.771144278607, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=41.9191919191919, Blast_Score=310, Evalue=1e-85,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 45148; Mature: 45148

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVINSGSSSLKYQILEMENESCLVKGLVERIGEQESDIEQENEGKEYKNITKIKDHE
CEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHCCCHHCCCHHHCCHHHHHHHHHHHHH
EALKKAMELITDPEYGCLKELNEIDAVGHRVVHGGEEFFSSVLIDEEVIKAIEENSDLAP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
LHNPPNLMGIRAAKKLLPNVPQVAVFDTSFHHSMPEKAYMYGLPYEVYQKYKIRRYGFHG
CCCCCCHHHHHHHHHHCCCCCCEEEEECHHHCCCCCHHEEECCCHHHHHHHHHHHCCCCC
TSHRYVSQKASEILKKDMKELKMITAHLGNGASLAAIDRGKVIDTSMGFTPLEGLIMGTR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCEEEECC
SGDIDPGIVFFLIRKGYSVDEVDDLLNKRSGVYGLSKMSNDMRDIRKGIENGDKKAKLAY
CCCCCCHHEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
DVYVYRLAKYIGSYITALKGLDVLVFTAGVGENDEHVRMDVCDYLDFFGVKIDKEKNTLL
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEHHHHHHHHHHHCCEECCCHHHHH
NRKNGIISASDSDVDILIVKTDEELMIAQDTKRIVEEVNEK
HCCCCEEEECCCCEEEEEEECCCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILVINSGSSSLKYQILEMENESCLVKGLVERIGEQESDIEQENEGKEYKNITKIKDHE
CEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHCCCHHCCCHHHCCHHHHHHHHHHHHH
EALKKAMELITDPEYGCLKELNEIDAVGHRVVHGGEEFFSSVLIDEEVIKAIEENSDLAP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
LHNPPNLMGIRAAKKLLPNVPQVAVFDTSFHHSMPEKAYMYGLPYEVYQKYKIRRYGFHG
CCCCCCHHHHHHHHHHCCCCCCEEEEECHHHCCCCCHHEEECCCHHHHHHHHHHHCCCCC
TSHRYVSQKASEILKKDMKELKMITAHLGNGASLAAIDRGKVIDTSMGFTPLEGLIMGTR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCEEEECC
SGDIDPGIVFFLIRKGYSVDEVDDLLNKRSGVYGLSKMSNDMRDIRKGIENGDKKAKLAY
CCCCCCHHEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
DVYVYRLAKYIGSYITALKGLDVLVFTAGVGENDEHVRMDVCDYLDFFGVKIDKEKNTLL
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEHHHHHHHHHHHCCEECCCHHHHH
NRKNGIISASDSDVDILIVKTDEELMIAQDTKRIVEEVNEK
HCCCCEEEECCCCEEEEEEECCCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571; 10074080 [H]