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The map label for this gene is fba [H]

Identifier: 160902119

GI number: 160902119

Start: 696272

End: 697210

Strand: Direct

Name: fba [H]

Synonym: Pmob_0646

Alternate gene names: 160902119

Gene position: 696272-697210 (Clockwise)

Preceding gene: 160902118

Following gene: 160902120

Centisome position: 32.09

GC content: 36.85

Gene sequence:

>939_bases
ATGCCTTACGTAAATACAAAGGATATTTTAGAAAAGGCGAATAAGGAATACTATGCGGTTGCAGCTTTCAACATTAACAA
TCTTGAGTTTCTCCAGGCTATAGTTGAAGGAGGGATAGAGAAAAAATCTCCTCTGATAATCGAAACAAGTGAAGGGGCAA
TGAAGTATGCTGGCATGGGTGATCCTTTGAGAGGAGCAAGCCTGTTTGTAAAAATGGTTAGAGAGTTTGCAGATTCTTTA
GATATACCAATCGCTCTGCATTTAGACCACGGGAAGAATTTTAAATATATAATATCCGCAATTAAAGCTGGTTATTCATC
TGTAATGATAGATGCATCTGATAAACCATTGGAAGAAAATCTAAAAGCTACGAAAGATATTGTAAGAATAGCCCATGCAG
CAGGTGTTTCAGTGGAAGCAGAATTAGGAAAGTTAGCTGGAATAGAAGACAACGTTGCTTCAGCTGAATCTGTTCTAGTT
AATCCCGATGAGGCGAAATATTTTGTAGAGGAAACCCAAGTTGATTTTCTAGCTCCGGCTATTGGCACTTCCCATGGAGC
ATTTAAGTTTAAAGGAGAAGCTAAATTAGACTTTGATAGATTGAAAAAAGTTAAAGAATTGACAAAAATGCCTTTGGTAC
TACACGGTGCTTCAAGTGTTGTGCAAGAAATGGTCGAAATAGCTGAAAATTATGGAGCTGATTTCGGAGGATCAAAAGGT
GTACCCTCAGATATATTGAAAGAAACCGTTCGATTAGGTATAAATAAAGTAAATACAGATACTGACCTTAGGATGGCTTT
TATTGCAGGATTAAGAGAATTCTTGCAGAACAATCCCAAAGAGTTTGATCCTAGAAAATACATGGAAACGGCAAAGTCTT
ATGTGAAAAAGGTTGTTTCAGATAGATTGGAGCTTTTAGGTTCTGCTAATAAAGCTTAA

Upstream 100 bases:

>100_bases
GACAATTAAAAGATAAAGAAGTAACTTAAAAAGGGCGCTACTAAAGTTTTAGAGACTCTAAAAATAATAACAAAAATTCA
ATAAAAGGAGGAAACAAATT

Downstream 100 bases:

>100_bases
TTCAAAGTACAGCCATGGCTTCCATGGTTGTACTTTTTTATTTTAACCAAAAATATTAACAGGAGGATTTCGAATGAAAA
TACTAGTGATCAACTCCGGA

Product: fructose-1,6-bisphosphate aldolase, class II

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPYVNTKDILEKANKEYYAVAAFNINNLEFLQAIVEGGIEKKSPLIIETSEGAMKYAGMGDPLRGASLFVKMVREFADSL
DIPIALHLDHGKNFKYIISAIKAGYSSVMIDASDKPLEENLKATKDIVRIAHAAGVSVEAELGKLAGIEDNVASAESVLV
NPDEAKYFVEETQVDFLAPAIGTSHGAFKFKGEAKLDFDRLKKVKELTKMPLVLHGASSVVQEMVEIAENYGADFGGSKG
VPSDILKETVRLGINKVNTDTDLRMAFIAGLREFLQNNPKEFDPRKYMETAKSYVKKVVSDRLELLGSANKA

Sequences:

>Translated_312_residues
MPYVNTKDILEKANKEYYAVAAFNINNLEFLQAIVEGGIEKKSPLIIETSEGAMKYAGMGDPLRGASLFVKMVREFADSL
DIPIALHLDHGKNFKYIISAIKAGYSSVMIDASDKPLEENLKATKDIVRIAHAAGVSVEAELGKLAGIEDNVASAESVLV
NPDEAKYFVEETQVDFLAPAIGTSHGAFKFKGEAKLDFDRLKKVKELTKMPLVLHGASSVVQEMVEIAENYGADFGGSKG
VPSDILKETVRLGINKVNTDTDLRMAFIAGLREFLQNNPKEFDPRKYMETAKSYVKKVVSDRLELLGSANKA
>Mature_311_residues
PYVNTKDILEKANKEYYAVAAFNINNLEFLQAIVEGGIEKKSPLIIETSEGAMKYAGMGDPLRGASLFVKMVREFADSLD
IPIALHLDHGKNFKYIISAIKAGYSSVMIDASDKPLEENLKATKDIVRIAHAAGVSVEAELGKLAGIEDNVASAESVLVN
PDEAKYFVEETQVDFLAPAIGTSHGAFKFKGEAKLDFDRLKKVKELTKMPLVLHGASSVVQEMVEIAENYGADFGGSKGV
PSDILKETVRLGINKVNTDTDLRMAFIAGLREFLQNNPKEFDPRKYMETAKSYVKKVVSDRLELLGSANKA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=313, Percent_Identity=38.0191693290735, Blast_Score=213, Evalue=9e-57,
Organism=Escherichia coli, GI87082041, Length=314, Percent_Identity=37.2611464968153, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1788072, Length=304, Percent_Identity=31.9078947368421, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789293, Length=338, Percent_Identity=23.9644970414201, Blast_Score=85, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6322790, Length=362, Percent_Identity=23.7569060773481, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 34169; Mature: 34037

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYVNTKDILEKANKEYYAVAAFNINNLEFLQAIVEGGIEKKSPLIIETSEGAMKYAGMG
CCCCCHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCC
DPLRGASLFVKMVREFADSLDIPIALHLDHGKNFKYIISAIKAGYSSVMIDASDKPLEEN
CCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHH
LKATKDIVRIAHAAGVSVEAELGKLAGIEDNVASAESVLVNPDEAKYFVEETQVDFLAPA
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHCCCCEEECCCHHHHHHHHHHHHHHHHH
IGTSHGAFKFKGEAKLDFDRLKKVKELTKMPLVLHGASSVVQEMVEIAENYGADFGGSKG
HCCCCCCEEECCCCCCCHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
VPSDILKETVRLGINKVNTDTDLRMAFIAGLREFLQNNPKEFDPRKYMETAKSYVKKVVS
CCHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DRLELLGSANKA
HHHHHHHCCCCC
>Mature Secondary Structure 
PYVNTKDILEKANKEYYAVAAFNINNLEFLQAIVEGGIEKKSPLIIETSEGAMKYAGMG
CCCCHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCC
DPLRGASLFVKMVREFADSLDIPIALHLDHGKNFKYIISAIKAGYSSVMIDASDKPLEEN
CCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHH
LKATKDIVRIAHAAGVSVEAELGKLAGIEDNVASAESVLVNPDEAKYFVEETQVDFLAPA
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHCCCCEEECCCHHHHHHHHHHHHHHHHH
IGTSHGAFKFKGEAKLDFDRLKKVKELTKMPLVLHGASSVVQEMVEIAENYGADFGGSKG
HCCCCCCEEECCCCCCCHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
VPSDILKETVRLGINKVNTDTDLRMAFIAGLREFLQNNPKEFDPRKYMETAKSYVKKVVS
CCHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DRLELLGSANKA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]