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The map label for this gene is fucA [H]

Identifier: 160902115

GI number: 160902115

Start: 692861

End: 693508

Strand: Direct

Name: fucA [H]

Synonym: Pmob_0642

Alternate gene names: 160902115

Gene position: 692861-693508 (Clockwise)

Preceding gene: 160902114

Following gene: 160902116

Centisome position: 31.94

GC content: 33.33

Gene sequence:

>648_bases
ATGTTACTAGCTGAAGAAAGGAAAATGATAGCAGAATATGGTAAGAAACTTATTGATTCAGGCTTGACTACTGGAACTGG
TGGCAATATAAGTATTTTTAATCGTGATCAACAATTAATGGCTATAACTCCTTCAGGTGTTCCCTATCATAATATTTCAC
CAGAAGATGTGGCAGTTCTGGATTTAAATAATAACATTCTAGATAGCAACAAAAAACCTTCTAGTGAATACGAAATGCAC
AAAATATTTTATGAAAAGAGGAAAAATGTTACTGCAGTTGTACATACTCATTCGGTTTATGCAACTACTATTGCTTGCTT
GAATTGGGAATTACCAGCTGTTCATTATCTCATTGGTTATGCTGGGAGTAAGGTTCCGTTAGCAAAATATGCCACCTTTG
GAACAAAAGAGTTAGCAAAAAACGCTTATCAAGCTATGGGAAATTATAATGCCGTTTTATTAGCAAATCATGGGCTTTTA
GCAGTAGGAAAGGATATAGATTGGGCTTTTAATACTGCAGAGGAAATAGAATTTACTTGTCAGATTTATTATCAGACTAA
AACTATTGGTGAACCCGTTATTTTATCTTCTGAAGAAATGAAAAAAATCATGGAAAAATTTGATAGCTACGGTCAGATAC
AAAAATAG

Upstream 100 bases:

>100_bases
TGGTAATTCGAAGGAAAAAACTTAATAGCATTGAAGATTTTATTAAAATAGTCCAAAAAATAACAAATCAGGAAGATGCT
TAATGTAGGAGGAGACAAAA

Downstream 100 bases:

>100_bases
CTAAAGATTTTAAAACCCTAAATAACCTGTCAACATTTTATATTTTAATGTTTACTTTGTTTCGTTTAGTAAGCCTAAAC
GCTATCTAAAAAATAGATAG

Product: class II aldolase/adducin family protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLLAEERKMIAEYGKKLIDSGLTTGTGGNISIFNRDQQLMAITPSGVPYHNISPEDVAVLDLNNNILDSNKKPSSEYEMH
KIFYEKRKNVTAVVHTHSVYATTIACLNWELPAVHYLIGYAGSKVPLAKYATFGTKELAKNAYQAMGNYNAVLLANHGLL
AVGKDIDWAFNTAEEIEFTCQIYYQTKTIGEPVILSSEEMKKIMEKFDSYGQIQK

Sequences:

>Translated_215_residues
MLLAEERKMIAEYGKKLIDSGLTTGTGGNISIFNRDQQLMAITPSGVPYHNISPEDVAVLDLNNNILDSNKKPSSEYEMH
KIFYEKRKNVTAVVHTHSVYATTIACLNWELPAVHYLIGYAGSKVPLAKYATFGTKELAKNAYQAMGNYNAVLLANHGLL
AVGKDIDWAFNTAEEIEFTCQIYYQTKTIGEPVILSSEEMKKIMEKFDSYGQIQK
>Mature_215_residues
MLLAEERKMIAEYGKKLIDSGLTTGTGGNISIFNRDQQLMAITPSGVPYHNISPEDVAVLDLNNNILDSNKKPSSEYEMH
KIFYEKRKNVTAVVHTHSVYATTIACLNWELPAVHYLIGYAGSKVPLAKYATFGTKELAKNAYQAMGNYNAVLLANHGLL
AVGKDIDWAFNTAEEIEFTCQIYYQTKTIGEPVILSSEEMKKIMEKFDSYGQIQK

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=215, Percent_Identity=39.5348837209302, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789094, Length=184, Percent_Identity=30.9782608695652, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790642, Length=195, Percent_Identity=27.6923076923077, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786247, Length=195, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790008, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 24039; Mature: 24039

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAEERKMIAEYGKKLIDSGLTTGTGGNISIFNRDQQLMAITPSGVPYHNISPEDVAVL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCEEEE
DLNNNILDSNKKPSSEYEMHKIFYEKRKNVTAVVHTHSVYATTIACLNWELPAVHYLIGY
ECCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHHEEECCCCHHHHHHHHC
AGSKVPLAKYATFGTKELAKNAYQAMGNYNAVLLANHGLLAVGKDIDWAFNTAEEIEFTC
CCCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCHHHEEEEE
QIYYQTKTIGEPVILSSEEMKKIMEKFDSYGQIQK
EEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLLAEERKMIAEYGKKLIDSGLTTGTGGNISIFNRDQQLMAITPSGVPYHNISPEDVAVL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCEEEE
DLNNNILDSNKKPSSEYEMHKIFYEKRKNVTAVVHTHSVYATTIACLNWELPAVHYLIGY
ECCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHHEEECCCCHHHHHHHHC
AGSKVPLAKYATFGTKELAKNAYQAMGNYNAVLLANHGLLAVGKDIDWAFNTAEEIEFTC
CCCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCHHHEEEEE
QIYYQTKTIGEPVILSSEEMKKIMEKFDSYGQIQK
EEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]