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The map label for this gene is oxaA [H]

Identifier: 160877622

GI number: 160877622

Start: 5344859

End: 5346484

Strand: Reverse

Name: oxaA [H]

Synonym: Sbal195_4521

Alternate gene names: 160877622

Gene position: 5346484-5344859 (Counterclockwise)

Preceding gene: 160877623

Following gene: 160877621

Centisome position: 99.99

GC content: 45.02

Gene sequence:

>1626_bases
ATGGAATCTCAACGCAATATATTGCTCATAGGACTACTGTTTGTCAGCTTTTTGCTGTGGCAACAGTGGCAAGCAGACAA
AGCTCCTAAACCAGTTGCAACCGAATCGTCCTTAGTGGCGAACGCGGCAAACTCACACAGTGCCGATGTTCCAGAAGCTG
ATACAGGTGTTCCTGCAGCAGTGACAGCAACCAGCAAACTGATTACCGTGAAAACCGACCAGTTGGATGTTCAAATTAAT
CCAATCGGTGGCGACATTGTTTTTGCTGCGTTAGTTTCACACAAGATGGAACAGGATAAAGATCAACCCTTCGTGTTGCT
TGAGCAAACGAAAGATTTCACTTATATAGCCCAGAGCGGTCTTATAGGTCGCGATGGTATAGACAGTAGCGCCAAAGGCC
GTGCCGCATTTAGCACTGCAGCGACTGAATATACCTTAGCCGAAGGTCAAGACACTTTAGAAGTGCCATTAACTTATGTA
GCCGACAATGGCGTGACATACACTAAAGTGTTTGTATTCCATCGCGGTAAGTTCAACGTCGATGTTGACTATAAAATCAA
CAACACTTCAGCGGCTCCGCTGCAAGTTCAGATGTACGGTCAAATTAAACAAACGATTAAACCGTCTGAAAGCAGCATGG
TTATGCCTACCTACCGTGGTGGTGCATTCTCTACGCAAGATGTGCGTTATGAGAAATACAAATTTGATGACATGGCGAAA
AGCAACCTGAACCAAGCGACGTTGGGCGGTTGGGCTGCCATGCTACAACATTACTTCGTTTCAGCTTGGATCCCACCAGC
TACCGACAGCAACACTATTTTCTCTAGTGTCAGTGCGGGCGGTTTAGCCAATATTGGTTTCCGCGGCGCGGTATATGATA
TTGCACCAGGTGCGACTCAAGAAATTAGCTCACAATTCTACGTTGGTCCTAAGGATCAAAAAGCACTGTCAGCCATCTCT
GATACCTTAAACCTAGTGGTCGATTACGGCTTCCTATGGTGGTTAGCAGTACCTATTCACTGGCTATTGATGTTCTATCA
ATCATTCGTCGGTAACTGGGGTTTGGCTATTATTCTGATCACCTTAACCGTTCGTGGTTTACTGTTCCCGCTGACAAAAG
CGCAGTACACCTCAATGGCGAAGATGCGTAACCTGCAACCTAAACTGACTGACTTGAAAGAACGCTTTGGTGATGACCGT
CAAAAGATGGGTCAGGCCATGATGGAACTGTATAAGAAAGAAAAAGTTAACCCTATGGGTGGCTGTTTACCTATTATTTT
ACAGATGCCAATCTTCATTGCCTTGTACTGGGTATTGTTAGAAAGCTTCGAATTACGTCACGCACCCTTTATGTTGTGGA
TCCACGATTTATCGGTACAAGATCCTTACTACATACTGCCATTGCTGATGGGCGTATCAATGTTTGTGATGCAGAAGATG
CAACCTATTGCACCGACTATGGACCCAATGCAAGTGAAAATGATGCAGTGGATGCCAGTGATCTTTACCGTATTCTTCCT
CTGGTTCCCAGCGGGTCTAGTACTGTACTGGTTAGTGGGTAACATCGTTGCTATCACGCAACAGAAGATTATTTATGCAG
GTCTAGCGAAAAAAGGCTTAAAATAA

Upstream 100 bases:

>100_bases
TTGTTGGTTTGCATTGAAACGCATATTAAAATGTCACCCTTTACATCCCGGCGGTAGTGATCCCGTCCCCCCTAAAAATG
ACAGGTGTAATAAATAGGCT

Downstream 100 bases:

>100_bases
GCCTAAGATTTGCAAGACTCTAGCGCATCGTTACAGATTAATGTGAACGAATGACACTAAAAGGCGGCTTAATTGGCCGC
CTTTTCCTTTACATATTTTA

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAAVTATSKLITVKTDQLDVQIN
PIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYV
ADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSAIS
DTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGLAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDR
QKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGLK

Sequences:

>Translated_541_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAAVTATSKLITVKTDQLDVQIN
PIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYV
ADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSAIS
DTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGLAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDR
QKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGLK
>Mature_541_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAAVTATSKLITVKTDQLDVQIN
PIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYV
ADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSAIS
DTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGLAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDR
QKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGLK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=548, Percent_Identity=52.007299270073, Blast_Score=566, Evalue=1e-162,
Organism=Drosophila melanogaster, GI24662345, Length=198, Percent_Identity=25.2525252525253, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356443, Length=198, Percent_Identity=25.2525252525253, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 60362; Mature: 60362

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAA
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEE
VTATSKLITVKTDQLDVQINPIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSG
EECCCEEEEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHCC
LIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNV
CCCCCCCCCCCCCCCHHHHHHCEEEECCCCCCEECCEEEEECCCCEEEEEEEEECCEEEE
DVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
EEEEEECCCCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHCCHHHHH
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCHH
EISSQFYVGPKDQKALSAISDTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGLAIILI
HHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDRQKMGQAMMELYKKEKVNPMG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
GCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C
>Mature Secondary Structure
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAA
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEE
VTATSKLITVKTDQLDVQINPIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSG
EECCCEEEEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHCC
LIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNV
CCCCCCCCCCCCCCCHHHHHHCEEEECCCCCCEECCEEEEECCCCEEEEEEEEECCEEEE
DVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
EEEEEECCCCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHCCHHHHH
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCHH
EISSQFYVGPKDQKALSAISDTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGLAIILI
HHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDRQKMGQAMMELYKKEKVNPMG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
GCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA