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The map label for this gene is ompR [H]

Identifier: 160877440

GI number: 160877440

Start: 5127651

End: 5128376

Strand: Direct

Name: ompR [H]

Synonym: Sbal195_4338

Alternate gene names: 160877440

Gene position: 5127651-5128376 (Clockwise)

Preceding gene: 160877434

Following gene: 160877441

Centisome position: 95.89

GC content: 54.96

Gene sequence:

>726_bases
ATGGGACAAGAAACCTCGAAAATCCTCGTCGTCGATGATGATATGCGCCTGCGAGCGTTACTCGAGCGTTACCTGATGGA
GCAAGGTTATCAGGTGCGCAGCGCGGCCAATGCCGAGCAGATGGACCGCCTATTAGAACGCGAAAACTTCCATTTACTCG
TGCTCGACTTGATGTTACCCGGTGAAGATGGCCTATCTATCTGCCGCCGTTTGCGCCAGCAAGGTAATCCTATTCCGATC
GTGATGCTGACGGCCAAGGGCGATGAAGTCGACCGTATTATTGGCCTAGAGTTAGGCGCCGACGATTATCTGCCAAAACC
TTTCAATCCACGGGAATTACTCGCACGGATCAAAGCCGTGATGCGTCGCCAAACCCAAGATGTGCCCGGTGCGCCAGCCC
AGCAGGAAGCGCAGATCAGCTTCGGTGAGTTTTCGCTGGATTTAGCCACCCGTGAGATGTACCACGGCGACGAATCGATT
GCGCTCACCAGCGGTGAGTTTGCCGTGCTGAAAGTGCTCGTCACCCATCCACGCGAGCCCTTGTCTCGGGATAAATTGAT
GAACCTCGCCCGTGGTCGCGATTACTCGGCGCTAGAACGCTCCATCGACGTGCAAGTGTCACGTCTGCGGCGTTTAATCG
AGAAAGATCCTGCGAATCCGCGTTACATTCAAACTGTGTGGGGATTAGGTTATGTGTTTGTGCCCGATGGCGCCGCGCGT
CGATGA

Upstream 100 bases:

>100_bases
TATATTAGGCAGATTCGTTTTCAATTTCAGCCAGTTGGTTAATCTTAACTGTTTCTCGTCAGTAGAATAAGCACCAATCT
GAGCAATTAAAGGACATCCC

Downstream 100 bases:

>100_bases
GCCGCATTGCCATCTTAATCTGCTGCGGTTATTGAGCCCCCGATGAAACCTAAGTTTTGGTGGCGGTTTATGCCTCGCAG
CGCGTTTAGCCAAACCGTGA

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MGQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQQGNPIPI
VMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTQDVPGAPAQQEAQISFGEFSLDLATREMYHGDESI
ALTSGEFAVLKVLVTHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGAAR
R

Sequences:

>Translated_241_residues
MGQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQQGNPIPI
VMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTQDVPGAPAQQEAQISFGEFSLDLATREMYHGDESI
ALTSGEFAVLKVLVTHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGAAR
R
>Mature_240_residues
GQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQQGNPIPIV
MLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTQDVPGAPAQQEAQISFGEFSLDLATREMYHGDESIA
LTSGEFAVLKVLVTHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGAARR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=80.0847457627119, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=38.4279475982533, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=33.8983050847458, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=245, Percent_Identity=36.3265306122449, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=38.3620689655172, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=38.5593220338983, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.6521739130435, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=34.3220338983051, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=32.034632034632, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=34.4827586206897, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=37.280701754386, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=32.9004329004329, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=30.7359307359307, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.5991189427313, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=32.520325203252, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27386; Mature: 27255

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLP
CCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEEEEECC
GEDGLSICRRLRQQGNPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
MRRQTQDVPGAPAQQEAQISFGEFSLDLATREMYHGDESIALTSGEFAVLKVLVTHPREP
HHHHHCCCCCCCCCCCCEEECCCEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCC
LSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGAAR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCC
R
C
>Mature Secondary Structure 
GQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLP
CCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEEEEECC
GEDGLSICRRLRQQGNPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
MRRQTQDVPGAPAQQEAQISFGEFSLDLATREMYHGDESIALTSGEFAVLKVLVTHPREP
HHHHHCCCCCCCCCCCCEEECCCEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCC
LSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGAAR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]