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The map label for this gene is bioH [H]

Identifier: 160877433

GI number: 160877433

Start: 5114662

End: 5115456

Strand: Direct

Name: bioH [H]

Synonym: Sbal195_4331

Alternate gene names: 160877433

Gene position: 5114662-5115456 (Clockwise)

Preceding gene: 160877425

Following gene: 160877434

Centisome position: 95.65

GC content: 50.44

Gene sequence:

>795_bases
GTGAGCCAAGTGACATCCACAAACCACGCAAATTTGCATATTGAAATCAGAGGCCAAGGGCCAGATCTGGTGATGCTTCA
CGGTTGGGGAGTCAATAGCGCTGTGTTTACGCCATTACATGAGTCACTGTCTCAGTATAGGGTGCACTATGTCGACTTGC
CGGGCTTCGGCCATAGTCAGATGGTGGAAGGTGATCTATTCGCTTGGGTCGATGCCTTAGTCGCCGCATTACCAGAACAC
GCTATTTGGGCCGGCTGGTCACTCGGTGGGCTCGTGGCGACTCAGGCAGCACTGAGTTATCCACAAAAAATCAAAGGCTT
GATTACTATTGCCTCATCCCCTTGCTTTATGGCAAGGGAAGACGAAGCATGGCCGGGCATTCCGCCACAAGTTCTTAATC
AATTTAGAGAACAACTTGGGCAAAATTTACCTAAAACCATTGAGAGATTTCTGGCGATTCAGGCCATGGGCAGCGCAACC
GCTAAAGAAGATATCAAACGGCTGCGCGATCTTGTGCTTGCGCGTCCGTTACCCGATGCCAGAGCCTTAACTCAAGGTCT
GAGTATGCTGACCGACATCGACCTAAGGCCGCAACTGACAGAATTGCAGCAACCTTGGCTTAGAATTTGGGGCCGACTCG
ATGGACTCGTCCCCAAACGCGTACAACCTAAGATGCCGATCACGCCGCAAATTGAAGATGTGATGCTAGCCAAAGCCTCC
CATGCGCCGTTTATTTCCCATCAACAGGAGTTTTTGCAGGTATTTATGCCTTGGTTAGCGTTACAGACACGCTAA

Upstream 100 bases:

>100_bases
AGTTGATAGCCTAAACGCATAATCCGCAAAGCAGATTGCGGCCAAATCCTTTTGACAAAGTGCGGCATACATTCACCTAA
TCCATTTTTGAGGCACTCAA

Downstream 100 bases:

>100_bases
CGCTTTATCTTTGAGCGATTAATGACTAGTATTTAACCATTAGTGCACCAAGGAATTTTCCATGTTAGTTGTCAGTAACT
ACCCACAAGTCCCACTAGCG

Product: bioH protein

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSQVTSTNHANLHIEIRGQGPDLVMLHGWGVNSAVFTPLHESLSQYRVHYVDLPGFGHSQMVEGDLFAWVDALVAALPEH
AIWAGWSLGGLVATQAALSYPQKIKGLITIASSPCFMAREDEAWPGIPPQVLNQFREQLGQNLPKTIERFLAIQAMGSAT
AKEDIKRLRDLVLARPLPDARALTQGLSMLTDIDLRPQLTELQQPWLRIWGRLDGLVPKRVQPKMPITPQIEDVMLAKAS
HAPFISHQQEFLQVFMPWLALQTR

Sequences:

>Translated_264_residues
MSQVTSTNHANLHIEIRGQGPDLVMLHGWGVNSAVFTPLHESLSQYRVHYVDLPGFGHSQMVEGDLFAWVDALVAALPEH
AIWAGWSLGGLVATQAALSYPQKIKGLITIASSPCFMAREDEAWPGIPPQVLNQFREQLGQNLPKTIERFLAIQAMGSAT
AKEDIKRLRDLVLARPLPDARALTQGLSMLTDIDLRPQLTELQQPWLRIWGRLDGLVPKRVQPKMPITPQIEDVMLAKAS
HAPFISHQQEFLQVFMPWLALQTR
>Mature_263_residues
SQVTSTNHANLHIEIRGQGPDLVMLHGWGVNSAVFTPLHESLSQYRVHYVDLPGFGHSQMVEGDLFAWVDALVAALPEHA
IWAGWSLGGLVATQAALSYPQKIKGLITIASSPCFMAREDEAWPGIPPQVLNQFREQLGQNLPKTIERFLAIQAMGSATA
KEDIKRLRDLVLARPLPDARALTQGLSMLTDIDLRPQLTELQQPWLRIWGRLDGLVPKRVQPKMPITPQIEDVMLAKASH
APFISHQQEFLQVFMPWLALQTR

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

Organism=Escherichia coli, GI1789817, Length=250, Percent_Identity=46.4, Blast_Score=226, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 29497; Mature: 29365

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVTSTNHANLHIEIRGQGPDLVMLHGWGVNSAVFTPLHESLSQYRVHYVDLPGFGHSQ
CCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCH
MVEGDLFAWVDALVAALPEHAIWAGWSLGGLVATQAALSYPQKIKGLITIASSPCFMARE
HHCHHHHHHHHHHHHHCCCHHEECCCCHHHHHHHHHHHHCHHHHCEEEEECCCCCEECCC
DEAWPGIPPQVLNQFREQLGQNLPKTIERFLAIQAMGSATAKEDIKRLRDLVLARPLPDA
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHH
RALTQGLSMLTDIDLRPQLTELQQPWLRIWGRLDGLVPKRVQPKMPITPQIEDVMLAKAS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCC
HAPFISHQQEFLQVFMPWLALQTR
CCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQVTSTNHANLHIEIRGQGPDLVMLHGWGVNSAVFTPLHESLSQYRVHYVDLPGFGHSQ
CCCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCH
MVEGDLFAWVDALVAALPEHAIWAGWSLGGLVATQAALSYPQKIKGLITIASSPCFMARE
HHCHHHHHHHHHHHHHCCCHHEECCCCHHHHHHHHHHHHCHHHHCEEEEECCCCCEECCC
DEAWPGIPPQVLNQFREQLGQNLPKTIERFLAIQAMGSATAKEDIKRLRDLVLARPLPDA
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHH
RALTQGLSMLTDIDLRPQLTELQQPWLRIWGRLDGLVPKRVQPKMPITPQIEDVMLAKAS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCC
HAPFISHQQEFLQVFMPWLALQTR
CCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA