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The map label for this gene is trxC [H]

Identifier: 160877133

GI number: 160877133

Start: 4739185

End: 4739697

Strand: Direct

Name: trxC [H]

Synonym: Sbal195_4029

Alternate gene names: 160877133

Gene position: 4739185-4739697 (Clockwise)

Preceding gene: 160877130

Following gene: 160877135

Centisome position: 88.63

GC content: 45.81

Gene sequence:

>513_bases
ATGGGCGAGATAATCATCACTCAGCCTTTAAATAATCGTCCGTTAGCCCAATATATTAGCCGTATAGACATTTTATTTTG
GAGCTTTGCCATGATTATTGCCTGCCCCCATTGCGATACATTAAACCGCGTTCCCGATGAGCGTGTAAACCAGCAACCTA
CTTGCGGTAAATGTAAGCTCAGTGTCTTTACGGCTGCGCCGATTGAACTCACTAGCGCAAACTTTGCCAACCATGCCAAA
AAATCTGAGCTTCCCCTAGTCGTTGATTTTTGGGCCAGCTGGTGTGGCCCCTGTAAAAGTTTTGCCCCGGTATTTTCCGC
GGCAGCTAAGACGTGGGAGCCGCAATTTCGCTTCGGTAAAATCAATACTGAAGAACAACAAGCCCTTGCGGCGCAATTTA
ATATTCGCTCGATTCCCACTCTTATGATTTTCAAGCAAGGGAAAATACTCGCACAGCAAGCGGGCGCTTTACCTCAGTCA
GCCTTAAATCAATGGTTAAAAAGCCATAGTTAA

Upstream 100 bases:

>100_bases
ACTTTGTGCAGGATTTTATCACCGACGACCACACTTGTCGGCGCTATTGCCACATTTCTGCGGCTCGGTTCACTGCTTTA
TTCTTGAGAATAAGTTCACC

Downstream 100 bases:

>100_bases
TCGCAGATAACTATTTCGCTCCCATAAAAATACCCAGACTCGCTGGGTATTTTGTTTTACGTGGATCTCAATCTACTGAC
ATCAGATATCCCAAAAAACA

Product: thioredoxin

Products: NA

Alternate protein names: Trx-2; Protein-disulfide reductase [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MGEIIITQPLNNRPLAQYISRIDILFWSFAMIIACPHCDTLNRVPDERVNQQPTCGKCKLSVFTAAPIELTSANFANHAK
KSELPLVVDFWASWCGPCKSFAPVFSAAAKTWEPQFRFGKINTEEQQALAAQFNIRSIPTLMIFKQGKILAQQAGALPQS
ALNQWLKSHS

Sequences:

>Translated_170_residues
MGEIIITQPLNNRPLAQYISRIDILFWSFAMIIACPHCDTLNRVPDERVNQQPTCGKCKLSVFTAAPIELTSANFANHAK
KSELPLVVDFWASWCGPCKSFAPVFSAAAKTWEPQFRFGKINTEEQQALAAQFNIRSIPTLMIFKQGKILAQQAGALPQS
ALNQWLKSHS
>Mature_169_residues
GEIIITQPLNNRPLAQYISRIDILFWSFAMIIACPHCDTLNRVPDERVNQQPTCGKCKLSVFTAAPIELTSANFANHAKK
SELPLVVDFWASWCGPCKSFAPVFSAAAKTWEPQFRFGKINTEEQQALAAQFNIRSIPTLMIFKQGKILAQQAGALPQSA
LNQWLKSHS

Specific function: Efficient electron donor for the essential enzyme ribonucleotide reductase. Is also able to reduce the interchain disulfide bridges of insulin [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=138, Percent_Identity=41.304347826087, Blast_Score=137, Evalue=3e-34,
Organism=Escherichia coli, GI87082331, Length=102, Percent_Identity=36.2745098039216, Blast_Score=91, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI212646193, Length=108, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554386, Length=104, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17549970, Length=81, Percent_Identity=34.5679012345679, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=100, Percent_Identity=35, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573567, Length=96, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921434, Length=81, Percent_Identity=35.8024691358025, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 18977; Mature: 18846

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEIIITQPLNNRPLAQYISRIDILFWSFAMIIACPHCDTLNRVPDERVNQQPTCGKCKL
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHCCCCCCCCCEEE
SVFTAAPIELTSANFANHAKKSELPLVVDFWASWCGPCKSFAPVFSAAAKTWEPQFRFGK
EEEEECCEEECCCCHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECC
INTEEQQALAAQFNIRSIPTLMIFKQGKILAQQAGALPQSALNQWLKSHS
CCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
GEIIITQPLNNRPLAQYISRIDILFWSFAMIIACPHCDTLNRVPDERVNQQPTCGKCKL
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHCCCCCCCCCEEE
SVFTAAPIELTSANFANHAKKSELPLVVDFWASWCGPCKSFAPVFSAAAKTWEPQFRFGK
EEEEECCEEECCCCHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECC
INTEEQQALAAQFNIRSIPTLMIFKQGKILAQQAGALPQSALNQWLKSHS
CCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]