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The map label for this gene is mlhB [H]

Identifier: 160876985

GI number: 160876985

Start: 4574311

End: 4575222

Strand: Reverse

Name: mlhB [H]

Synonym: Sbal195_3881

Alternate gene names: 160876985

Gene position: 4575222-4574311 (Counterclockwise)

Preceding gene: 160876986

Following gene: 160876984

Centisome position: 85.56

GC content: 48.9

Gene sequence:

>912_bases
ATGCCAAGCTGGCAAGCATCTGTACTGAATACTATTTTATCTTATGTTGCTAGGCCATCCATCAGTCGCGGCAAGGCCAA
AGTTCCCCTAGCGCAAGTGCGTAAAAAGTTGCTTGATCTCGATAAACGTTGGCTTCCTTGGCCGGATAAGTTAGTTAGTG
CCACCATCCCTTTGCAACACTCTAGCTTGCTGCACTATGTGCTTCTCAATGAGCAAACTCGCCTTGGCAATCTGTTTTAT
ATCCGAGGCGGAGGTTTTTGTTTTAAAACGCCCCATGCCCACGCAAGATTGATCGCGGATATTAGCCAACGTTGTAAATT
GGATGCCTATATTCCTGATTATCGTCTCGCACCTGAGCATCCTTTTCCTGCGCCATTTGATGATGTGCTTGAAGCCTATA
AGCGATTAATCGCGCTTAAGGGCGATGAGAATGTGATCCTCATGGGCGACTCTGCTGGCGGCAATTTAGCCCTGAGTTTG
TTGCTGGAATTAAAGCGTTTAGCCCTGCCTTTGCCGACGGCCTGTATCTTGTTATCGCCCGCGTTGGATTTAGCACTAAC
CGGAGATACTGAGCTGATACTCGCGGCTGACGATCCCTTCTTCACCATCGAAGCTTTGCTGCGTTTACGTGGCGCTTATC
TTGGGGGGGCCGACCCCATGTCAGCAAAAGTATCACCCTTGCAGGGGGACTTGGCAGATCTGCCGCCTATCTTAGTGATT
GCGGGTACGCGGGAGCTGTTATTGCAGGATTCTGAGCGCTTAGTCGCTCAAGTCAAAGCCAGCGGTGGCGATATAACGGG
CTGTTTTTACCCTAACATGCCCCATGTGTTTCCCTTGTTCAATTTATTGCCTGAAGCCCTTGAAGTGAGGTCGAAAATTA
GCCATTTTGTGCTTTCACACTTGATTCGTTAA

Upstream 100 bases:

>100_bases
CTGCGCTTAAAAGCACAGAATTATAGGAAGTTAGATCTGCTGTAGTCCACGACCTGCGACTTGAGCGTCGGGATGGCGGC
GTTTAAGTAGAGGAAGGGAT

Downstream 100 bases:

>100_bases
AATGGTGTAGTTATTCACATTCAGTGAATAGCTAGCAAAATGAGGGGTAAATAACTTTTTTTCTGACTAATTATGCTGAA
AGCCACGGGCATAACCGCTT

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQHSSLLHYVLLNEQTRLGNLFY
IRGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEHPFPAPFDDVLEAYKRLIALKGDENVILMGDSAGGNLALSL
LLELKRLALPLPTACILLSPALDLALTGDTELILAADDPFFTIEALLRLRGAYLGGADPMSAKVSPLQGDLADLPPILVI
AGTRELLLQDSERLVAQVKASGGDITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSHLIR

Sequences:

>Translated_303_residues
MPSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQHSSLLHYVLLNEQTRLGNLFY
IRGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEHPFPAPFDDVLEAYKRLIALKGDENVILMGDSAGGNLALSL
LLELKRLALPLPTACILLSPALDLALTGDTELILAADDPFFTIEALLRLRGAYLGGADPMSAKVSPLQGDLADLPPILVI
AGTRELLLQDSERLVAQVKASGGDITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSHLIR
>Mature_302_residues
PSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQHSSLLHYVLLNEQTRLGNLFYI
RGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEHPFPAPFDDVLEAYKRLIALKGDENVILMGDSAGGNLALSLL
LELKRLALPLPTACILLSPALDLALTGDTELILAADDPFFTIEALLRLRGAYLGGADPMSAKVSPLQGDLADLPPILVIA
GTRELLLQDSERLVAQVKASGGDITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSHLIR

Specific function: Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone der

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Caenorhabditis elegans, GI115533412, Length=145, Percent_Identity=30.3448275862069, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115533410, Length=145, Percent_Identity=30.3448275862069, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.83 [H]

Molecular weight: Translated: 33319; Mature: 33188

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQH
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEECCCCH
SSLLHYVLLNEQTRLGNLFYIRGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEH
HHHEEEEEECCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHCEECCCCCCCCCCCCC
PFPAPFDDVLEAYKRLIALKGDENVILMGDSAGGNLALSLLLELKRLALPLPTACILLSP
CCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCC
ALDLALTGDTELILAADDPFFTIEALLRLRGAYLGGADPMSAKVSPLQGDLADLPPILVI
CCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEE
AGTRELLLQDSERLVAQVKASGGDITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSH
ECCHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIR
HCC
>Mature Secondary Structure 
PSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQH
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEECCCCH
SSLLHYVLLNEQTRLGNLFYIRGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEH
HHHEEEEEECCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHCEECCCCCCCCCCCCC
PFPAPFDDVLEAYKRLIALKGDENVILMGDSAGGNLALSLLLELKRLALPLPTACILLSP
CCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCC
ALDLALTGDTELILAADDPFFTIEALLRLRGAYLGGADPMSAKVSPLQGDLADLPPILVI
CCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEE
AGTRELLLQDSERLVAQVKASGGDITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSH
ECCHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIR
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA