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The map label for this gene is ptxR [H]

Identifier: 160876896

GI number: 160876896

Start: 4470752

End: 4471639

Strand: Reverse

Name: ptxR [H]

Synonym: Sbal195_3792

Alternate gene names: 160876896

Gene position: 4471639-4470752 (Counterclockwise)

Preceding gene: 160876899

Following gene: 160876895

Centisome position: 83.62

GC content: 46.73

Gene sequence:

>888_bases
ATGAATCTCACCCATCTGCAGTCATTTATGCTGGTTGCCAAAATGCACAGTTTTAGCGCTGCGTCTGAACAACTCGGCGC
TTCTAAAGGCTTAGTGTCGCGCCATGTTAAATCCCTTGAAGATGAAATGGGTTGTCAATTACTCCACCGAACCACTCGGC
GAGTATCAATGACCGAAGCGGGGCAAGCGTTATTTGGTAAAGCCTGCGAAATCGAGAGGCTGGCAAATGAAGCTGGGCGT
TTAGTGCAGGATTTAACGCAGGACTCCTGCGGCACTTTAAAATTCACCGCTCCAACGGAACTGGGCAAAAAATTGCTGAG
TCCTATGCTGCTCCAGTTTATTGCTGCGTATCCTCAAGTGAAACTCGAACTGTGTTTTGAGCAGAATATTCAAGATGTTG
AGTTCGGCAAGTTTGATCTCGCCTTAAGAACAAGCATTGCGCACAGCGATAATATTATCGCCAGATATCTTGGCAGAATT
CGCCATGTCTTAGTGGTTGCGCCCGCACATCCCGCCGCCGCAGAGGTTCGTCACCCTGATGATTTACACCATTATCGTCT
ATTGTCTTCGGGTGAAACTCAGTGGGTGTTTGAACCGCTCGCTGGGGACAGTCTCACGCTCACTTTTGAGCCTACACTGT
GTAGTTCAAACTATGCCACTACACATTTGCTTACTTTGAGTGGTACAGGTATCGCTAGCCTGCCTTATTATTTGGTAGAG
GAGGATATCGCTCAGCATAAACTCACTTTGCTCGTTCCCCAATGGCAATGCTATCCACATGAGTTGTATATGGTTTATGC
CAAGCAGAGCCATTACCCAAAGAAGCTGCGCGATTTACAAAATAAGCTACAAACTTGGTGCGAAACTCACTCAAAATATG
TGGGTTAA

Upstream 100 bases:

>100_bases
TGACATGCTCCAAAATTGAATACGAATTAAGGATAGTCTGCTTAATTAAATAGAAAAAGCGCATATAATCACCACATTGT
TTCGTTAATGGATTTAATTG

Downstream 100 bases:

>100_bases
TGAGTCAAAGCGTCATCGCATCAAATCTTATCCGGCAGAGGGCGGAGCTTTTAGAATAAAGTGAGGCAGAGTACACTGCC
GCGCATTGAATTTTGTATTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNLTHLQSFMLVAKMHSFSAASEQLGASKGLVSRHVKSLEDEMGCQLLHRTTRRVSMTEAGQALFGKACEIERLANEAGR
LVQDLTQDSCGTLKFTAPTELGKKLLSPMLLQFIAAYPQVKLELCFEQNIQDVEFGKFDLALRTSIAHSDNIIARYLGRI
RHVLVVAPAHPAAAEVRHPDDLHHYRLLSSGETQWVFEPLAGDSLTLTFEPTLCSSNYATTHLLTLSGTGIASLPYYLVE
EDIAQHKLTLLVPQWQCYPHELYMVYAKQSHYPKKLRDLQNKLQTWCETHSKYVG

Sequences:

>Translated_295_residues
MNLTHLQSFMLVAKMHSFSAASEQLGASKGLVSRHVKSLEDEMGCQLLHRTTRRVSMTEAGQALFGKACEIERLANEAGR
LVQDLTQDSCGTLKFTAPTELGKKLLSPMLLQFIAAYPQVKLELCFEQNIQDVEFGKFDLALRTSIAHSDNIIARYLGRI
RHVLVVAPAHPAAAEVRHPDDLHHYRLLSSGETQWVFEPLAGDSLTLTFEPTLCSSNYATTHLLTLSGTGIASLPYYLVE
EDIAQHKLTLLVPQWQCYPHELYMVYAKQSHYPKKLRDLQNKLQTWCETHSKYVG
>Mature_295_residues
MNLTHLQSFMLVAKMHSFSAASEQLGASKGLVSRHVKSLEDEMGCQLLHRTTRRVSMTEAGQALFGKACEIERLANEAGR
LVQDLTQDSCGTLKFTAPTELGKKLLSPMLLQFIAAYPQVKLELCFEQNIQDVEFGKFDLALRTSIAHSDNIIARYLGRI
RHVLVVAPAHPAAAEVRHPDDLHHYRLLSSGETQWVFEPLAGDSLTLTFEPTLCSSNYATTHLLTLSGTGIASLPYYLVE
EDIAQHKLTLLVPQWQCYPHELYMVYAKQSHYPKKLRDLQNKLQTWCETHSKYVG

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=30.1003344481605, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87081978, Length=284, Percent_Identity=29.9295774647887, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=27.208480565371, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=25.8389261744966, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786401, Length=264, Percent_Identity=30.3030303030303, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787589, Length=275, Percent_Identity=24.3636363636364, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=25.938566552901, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=25.2559726962457, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788748, Length=143, Percent_Identity=32.1678321678322, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=172, Percent_Identity=26.1627906976744, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789492, Length=297, Percent_Identity=23.9057239057239, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788296, Length=181, Percent_Identity=28.7292817679558, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33196; Mature: 33196

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTHLQSFMLVAKMHSFSAASEQLGASKGLVSRHVKSLEDEMGCQLLHRTTRRVSMTEA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQALFGKACEIERLANEAGRLVQDLTQDSCGTLKFTAPTELGKKLLSPMLLQFIAAYPQV
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCC
KLELCFEQNIQDVEFGKFDLALRTSIAHSDNIIARYLGRIRHVLVVAPAHPAAAEVRHPD
EEEHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHEEEEEECCCCCHHCCCCCC
DLHHYRLLSSGETQWVFEPLAGDSLTLTFEPTLCSSNYATTHLLTLSGTGIASLPYYLVE
HHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCCHHHCCHHHHH
EDIAQHKLTLLVPQWQCYPHELYMVYAKQSHYPKKLRDLQNKLQTWCETHSKYVG
HHHHHCEEEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLTHLQSFMLVAKMHSFSAASEQLGASKGLVSRHVKSLEDEMGCQLLHRTTRRVSMTEA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQALFGKACEIERLANEAGRLVQDLTQDSCGTLKFTAPTELGKKLLSPMLLQFIAAYPQV
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCC
KLELCFEQNIQDVEFGKFDLALRTSIAHSDNIIARYLGRIRHVLVVAPAHPAAAEVRHPD
EEEHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHEEEEEECCCCCHHCCCCCC
DLHHYRLLSSGETQWVFEPLAGDSLTLTFEPTLCSSNYATTHLLTLSGTGIASLPYYLVE
HHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCCHHHCCHHHHH
EDIAQHKLTLLVPQWQCYPHELYMVYAKQSHYPKKLRDLQNKLQTWCETHSKYVG
HHHHHCEEEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]