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The map label for this gene is rtn [H]

Identifier: 160876833

GI number: 160876833

Start: 4395575

End: 4397095

Strand: Reverse

Name: rtn [H]

Synonym: Sbal195_3729

Alternate gene names: 160876833

Gene position: 4397095-4395575 (Counterclockwise)

Preceding gene: 160876834

Following gene: 160876828

Centisome position: 82.23

GC content: 43.06

Gene sequence:

>1521_bases
ATGCGAAGAAAAATAGCAAAATTAAATCTGCCATTGTGGCAATGGCTGGCAGTGATATTGTTTCCCATCGGGGTTGCTGT
GGTCGCAAGTTATCTTTCTGCACAGTATTTTGTGGAAGATAAAGTCAAAGGTGTGGGAGCTATTTATGTAGGCCACATAG
ATACGTTGATCTCTCATGCCGATGAAATCAGCCATTATGCATTGGCATTGAAGGATTCTGAGTGCCAAGAGTTATACAAC
TATATGTTGTTCCAACCTTACTTCCGCTCTGCTTTAATATTTGATTCACAACGTGTTTATTGTTCATCTAAAACAGGTGA
TATTGACGTACCTTTAGGCATAGTCAGTGCCACTGAAAATCTTGAAATACCTAACCAGTTTATTATTGGCGGCACGCCTT
TTATGCCTGAGGTGCCAGCGATAGTGGCATCAAACTGGGAACCGATATCTCAGCACGGCGCCGCTGTGATTATTGAAGGG
AAATATTTAGTAGATTCCTTTGTACAGCCCGATGTGTTCCCTAGCGCTGTTGTGAATGTTGCTTTAGCAATCAATGGTAA
AACGATTCCAGAGTCACTCGGATTTATGAAAAATGAGGTGATGACGCTCGATTCTGATAAGCACAATTTTTCAGTGTTAC
TAGAAATGTCACCTGCTTTTTTCTGGCATTTCTTTTGGATATTTTTGGCCATCTCTTTGCCCGTTAGTATCGGCTTGATT
ACGGGGACTATCCTATTTGTGCTCTATTCAAGGGTCACTCGCCATTCCCTCGCCGATGACATTCGCAGTGGGATAGAAAA
CGAAGAGTTTTTCTTAGTTTATCAGCCAGTGATTTGTGCCGAGGACGGTAAGGCCAAGGGCGTTGAAGCATTAGTGCGTT
GGCAGCATCCGCAAATGGGCTTAGTGCGGCCTGATTTGTTTATTCCCATTGCCGAAGAGGGCAAGTTAATCGTCCCATTG
ACTAACTATATTTTTGAGCGGGCATTAAAAGATTTTGCCGATATCGAGGTCGAACCGGGTTTTAGAATTGCGTTTAACGT
GGCGCCAGAACACTTTACGCAGGATGATATTGAGTCGAAATTTATTCATCTGCGGGATTCACTGGAACGTATTGGCGTTA
AGCCTTTGATTGAAATCACCGAACGGCAATTGTTAACGCCGGATATTTGCCAGTGCATTGAAAGCTTGCGACAGTTAGGA
ATTCTTGTGGCAATCGATGACTTTGGTACTGGGCAAACCACTTTATCCCTGCTGCAAACGATGCCGTTAGACTATCTGAA
AATTGATAAATGCTTTATCGATACCATAGGGCAAGATTCTGTCACTTCCCATGTGCTCGATACTATTATCGAGCTCTCCC
ACAAGATGAACTATATTGTGGTGGCAGAGGGGGTTGAGACGCAGGAGCAGGCGGATTATTTAACCAGTCGCCAAGTGCAT
TTTTTACAAGGATATCTTTTTGCAAAGCCGATGAAGCTGGCTGATTTAAAGTTATGGTTAGTCGAGCATTTTAAACGTTA
G

Upstream 100 bases:

>100_bases
GACATGAACTGAGATACAAACATATACACGTCTTGCAGCTTAGATTTTGATACCATTTTTAACCGAGTGCTGTGCGAGTT
AAGGAACTAAACAGAGAACT

Downstream 100 bases:

>100_bases
CATCATAAAATCAGTCAGCAATAAGGGCACCTAGGTGCCCTTATTGCTGTTCAAGCGTTATAGCTTAAGTTGTAGCCTAA
AGCGTTTAAAGACTATAGCC

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGAIYVGHIDTLISHADEISHYALALKDSECQELYN
YMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSATENLEIPNQFIIGGTPFMPEVPAIVASNWEPISQHGAAVIIEG
KYLVDSFVQPDVFPSAVVNVALAINGKTIPESLGFMKNEVMTLDSDKHNFSVLLEMSPAFFWHFFWIFLAISLPVSIGLI
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMGLVRPDLFIPIAEEGKLIVPL
TNYIFERALKDFADIEVEPGFRIAFNVAPEHFTQDDIESKFIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLG
ILVAIDDFGTGQTTLSLLQTMPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYIVVAEGVETQEQADYLTSRQVH
FLQGYLFAKPMKLADLKLWLVEHFKR

Sequences:

>Translated_506_residues
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGAIYVGHIDTLISHADEISHYALALKDSECQELYN
YMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSATENLEIPNQFIIGGTPFMPEVPAIVASNWEPISQHGAAVIIEG
KYLVDSFVQPDVFPSAVVNVALAINGKTIPESLGFMKNEVMTLDSDKHNFSVLLEMSPAFFWHFFWIFLAISLPVSIGLI
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMGLVRPDLFIPIAEEGKLIVPL
TNYIFERALKDFADIEVEPGFRIAFNVAPEHFTQDDIESKFIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLG
ILVAIDDFGTGQTTLSLLQTMPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYIVVAEGVETQEQADYLTSRQVH
FLQGYLFAKPMKLADLKLWLVEHFKR
>Mature_506_residues
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGAIYVGHIDTLISHADEISHYALALKDSECQELYN
YMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSATENLEIPNQFIIGGTPFMPEVPAIVASNWEPISQHGAAVIIEG
KYLVDSFVQPDVFPSAVVNVALAINGKTIPESLGFMKNEVMTLDSDKHNFSVLLEMSPAFFWHFFWIFLAISLPVSIGLI
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMGLVRPDLFIPIAEEGKLIVPL
TNYIFERALKDFADIEVEPGFRIAFNVAPEHFTQDDIESKFIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLG
ILVAIDDFGTGQTTLSLLQTMPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYIVVAEGVETQEQADYLTSRQVH
FLQGYLFAKPMKLADLKLWLVEHFKR

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=469, Percent_Identity=31.5565031982942, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI87081845, Length=515, Percent_Identity=29.126213592233, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87081980, Length=434, Percent_Identity=33.1797235023041, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1786507, Length=235, Percent_Identity=40.8510638297872, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87081743, Length=290, Percent_Identity=33.448275862069, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787541, Length=256, Percent_Identity=33.59375, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1790496, Length=304, Percent_Identity=30.9210526315789, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081921, Length=256, Percent_Identity=32.8125, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=29.5081967213115, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI226510982, Length=252, Percent_Identity=32.5396825396825, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082096, Length=245, Percent_Identity=29.7959183673469, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787055, Length=244, Percent_Identity=30.7377049180328, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 57093; Mature: 57093

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGAIYVGHIDTLISHA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHH
DEISHYALALKDSECQELYNYMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSATEN
HHHHHHEEEECCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCEECCEEEEECCCC
LEIPNQFIIGGTPFMPEVPAIVASNWEPISQHGAAVIIEGKYLVDSFVQPDVFPSAVVNV
CCCCCEEEECCCCCCCCCCHHHHCCCCCHHHCCCEEEEECHHHHHHHCCCCCCHHHHEEE
ALAINGKTIPESLGFMKNEVMTLDSDKHNFSVLLEMSPAFFWHFFWIFLAISLPVSIGLI
EEEECCCCCHHHHHHHHHCEEEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECEEEECCCCCCCHHHHHHCCCCCCC
LVRPDLFIPIAEEGKLIVPLTNYIFERALKDFADIEVEPGFRIAFNVAPEHFTQDDIESK
CCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCEECCCCEEEEECCCCCCCHHHHHHH
FIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLGILVAIDDFGTGQTTLSLLQT
HHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
MPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYIVVAEGVETQEQADYLTSRQVH
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCHHH
FLQGYLFAKPMKLADLKLWLVEHFKR
HHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGAIYVGHIDTLISHA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHH
DEISHYALALKDSECQELYNYMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSATEN
HHHHHHEEEECCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCEECCEEEEECCCC
LEIPNQFIIGGTPFMPEVPAIVASNWEPISQHGAAVIIEGKYLVDSFVQPDVFPSAVVNV
CCCCCEEEECCCCCCCCCCHHHHCCCCCHHHCCCEEEEECHHHHHHHCCCCCCHHHHEEE
ALAINGKTIPESLGFMKNEVMTLDSDKHNFSVLLEMSPAFFWHFFWIFLAISLPVSIGLI
EEEECCCCCHHHHHHHHHCEEEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECEEEECCCCCCCHHHHHHCCCCCCC
LVRPDLFIPIAEEGKLIVPLTNYIFERALKDFADIEVEPGFRIAFNVAPEHFTQDDIESK
CCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCEECCCCEEEEECCCCCCCHHHHHHH
FIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLGILVAIDDFGTGQTTLSLLQT
HHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
MPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYIVVAEGVETQEQADYLTSRQVH
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCHHH
FLQGYLFAKPMKLADLKLWLVEHFKR
HHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]