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The map label for this gene is cat [H]

Identifier: 160876110

GI number: 160876110

Start: 3568531

End: 3569175

Strand: Direct

Name: cat [H]

Synonym: Sbal195_3001

Alternate gene names: 160876110

Gene position: 3568531-3569175 (Clockwise)

Preceding gene: 160876109

Following gene: 160876111

Centisome position: 66.74

GC content: 51.01

Gene sequence:

>645_bases
ATGTCTGCGCCAACGCCTAGATCAGAGCCGGCATCTTTGCCTGATTATCAAAGCCAGCATAAAAAGCGTCTCTCTTGGAT
GCCGTGGCTGTATTTTTCTTTAAAAGAGAAACATTTAGTTTGGGCAAAACCTTGGCAGGATGAGATCCAAGCAAAACTCT
GTGCCCTCGAAACGGTTAACATCGGCGAGCACTGTTTTATCGCCCCCGAAGCGCAGTTATTTGCCGAACCCAATCGTGAT
ATCCGCATGGGTAATCGCTGCATGATCGCCGCCGAGTGTTTTTTGCATGGGCCTATCACGCTAGGGGACGAAGTGGCGAT
TAATCATGGTTGCTCCTTCGATGGCGGCAGAGTCGGTATTCAGATTGGCAGCCAGACCCGCATCGCCAATAATGTCACTA
TTTATGCCTTCAACCATGGCATGGCGCCAGATACGCCCATCTATCAACAAGCTGCCAACTCCAAAGGTATTGTTATAGGT
AAAGATGTGTGGATTGGCGCTCAGGCCGGCATAGTCGATGGTGTGACCATTGGCGATCACGCTGTGGTGGGCATGGGCTG
CATAGTGACGAAAGATGTGCCCGACTGGGCGATAGTGGCAGGCAACCCCGCCAAAGTGATTGGCGATAGGCGTGATAAAA
GCTAA

Upstream 100 bases:

>100_bases
CGCCCTCTATGATTTAGATGTGTTCTGGCAAATGGCGGTCGATGATAATGACCAAGAATACATCTTGGTATTAGAACTCA
AACCGGGGAAATGTGGCTAA

Downstream 100 bases:

>100_bases
ATCGGCCAGCACAAATCGCATCTTAAATCGCTTTCCTTTGACTCAGTAATCTTCTCAAAAATGCTATTTGTCTCCCAGCT
AGTTGAATTTAACCTAAATA

Product: hexapaptide repeat-containing transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSAPTPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVNIGEHCFIAPEAQLFAEPNRD
IRMGNRCMIAAECFLHGPITLGDEVAINHGCSFDGGRVGIQIGSQTRIANNVTIYAFNHGMAPDTPIYQQAANSKGIVIG
KDVWIGAQAGIVDGVTIGDHAVVGMGCIVTKDVPDWAIVAGNPAKVIGDRRDKS

Sequences:

>Translated_214_residues
MSAPTPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVNIGEHCFIAPEAQLFAEPNRD
IRMGNRCMIAAECFLHGPITLGDEVAINHGCSFDGGRVGIQIGSQTRIANNVTIYAFNHGMAPDTPIYQQAANSKGIVIG
KDVWIGAQAGIVDGVTIGDHAVVGMGCIVTKDVPDWAIVAGNPAKVIGDRRDKS
>Mature_213_residues
SAPTPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVNIGEHCFIAPEAQLFAEPNRDI
RMGNRCMIAAECFLHGPITLGDEVAINHGCSFDGGRVGIQIGSQTRIANNVTIYAFNHGMAPDTPIYQQAANSKGIVIGK
DVWIGAQAGIVDGVTIGDHAVVGMGCIVTKDVPDWAIVAGNPAKVIGDRRDKS

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=90, Percent_Identity=45.5555555555556, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786537, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788345, Length=154, Percent_Identity=29.8701298701299, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=116, Percent_Identity=36.2068965517241, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 23348; Mature: 23217

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPTPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVN
CCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHHHEEEEEC
IGEHCFIAPEAQLFAEPNRDIRMGNRCMIAAECFLHGPITLGDEVAINHGCSFDGGRVGI
CCCEEEECCCHHEEECCCCCEECCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCCEEEE
QIGSQTRIANNVTIYAFNHGMAPDTPIYQQAANSKGIVIGKDVWIGAQAGIVDGVTIGDH
EECCCEEEECCEEEEEEECCCCCCCCHHHHHCCCCCEEEECCEEEECCCCCCCCEEECCC
AVVGMGCIVTKDVPDWAIVAGNPAKVIGDRRDKS
EEEEEEEEEECCCCCEEEEECCCHHEECCCCCCC
>Mature Secondary Structure 
SAPTPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVN
CCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHHHEEEEEC
IGEHCFIAPEAQLFAEPNRDIRMGNRCMIAAECFLHGPITLGDEVAINHGCSFDGGRVGI
CCCEEEECCCHHEEECCCCCEECCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCCEEEE
QIGSQTRIANNVTIYAFNHGMAPDTPIYQQAANSKGIVIGKDVWIGAQAGIVDGVTIGDH
EECCCEEEECCEEEEEEECCCCCCCCHHHHHCCCCCEEEECCEEEECCCCCCCCEEECCC
AVVGMGCIVTKDVPDWAIVAGNPAKVIGDRRDKS
EEEEEEEEEECCCCCEEEEECCCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]