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The map label for this gene is scoA [H]

Identifier: 160876088

GI number: 160876088

Start: 3537757

End: 3538461

Strand: Direct

Name: scoA [H]

Synonym: Sbal195_2978

Alternate gene names: 160876088

Gene position: 3537757-3538461 (Clockwise)

Preceding gene: 160876087

Following gene: 160876089

Centisome position: 66.16

GC content: 50.5

Gene sequence:

>705_bases
ATGGCAGGACTCAATAAAGTCGTCAGCAGCTATGAAGAAGCGTTAAACGGCTTATCAAACGACATGACCATTATGGTCGG
CGGCTTTGGCCTGTGCGGCATTCCCGAAGGCTTAATCAATCAAATGGTTAAGATGGGCGTTAACGGCTTAACTGCCATTT
CAAACAACGCGGGTGTTGACGACTTTGGCCTTGGCTTACTATTAAAACATCGCCAAATTGCCACTATGATCGCCTCTTAC
GTGGGCGAAAACGCCACTTTCGAGCAACAAATGCTCTCTGGCGAACTGAACGTAATTTTAACACCCCAAGGCACACTAGC
GGAAAAAATCCGTGCAGGTGGCGCAGGCATTCCGGCTTTTTTCACTGCAACAGGTTACGGCACGCCAGTCGCTGATGGCA
AGGAAACCCGCGAAATCAAAGGGCGCCATTACGTGTTAGAAGAGTCGCTGACCGCAGATTTTGCACTCGTGCGCGCATGG
AAAGCCGATACCATGGGTAATTTAGTGTTCCGTAAAACCGCCGCCAACTTTAACCCTATGATGGCGACCGCGGGCAAAAT
CACTGTGGTTGAAGCCGAGTTTATTGTTGAGCCGGGCGAGCTAGACCCAGATCATATCCACACGCCGGGCATCTATGTTG
ACCGCGTTATTCAAGGCACGTTCGAGAAACGTATCGAGCAGCGCACGGTAAAAGCCGCGAAATAA

Upstream 100 bases:

>100_bases
CCTGTTAGCAAAATAGAACAACAATAATTAACGACAACAACCGTTATTGAAAACGCGCGTTATTTCCCGCGCGTTTTATA
CAGCATAAAAGGACATCACA

Downstream 100 bases:

>100_bases
AAGGCGCTGGCAAAACCTTGAAACACAGTTAACGCAATTGGCACTTAGCTCCCTAAAGTAAACAACTAAGGGTAAAAACC
TAAGAGTGAAGACCAAAGCG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAGLNKVVSSYEEALNGLSNDMTIMVGGFGLCGIPEGLINQMVKMGVNGLTAISNNAGVDDFGLGLLLKHRQIATMIASY
VGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVADGKETREIKGRHYVLEESLTADFALVRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGTFEKRIEQRTVKAAK

Sequences:

>Translated_234_residues
MAGLNKVVSSYEEALNGLSNDMTIMVGGFGLCGIPEGLINQMVKMGVNGLTAISNNAGVDDFGLGLLLKHRQIATMIASY
VGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVADGKETREIKGRHYVLEESLTADFALVRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGTFEKRIEQRTVKAAK
>Mature_233_residues
AGLNKVVSSYEEALNGLSNDMTIMVGGFGLCGIPEGLINQMVKMGVNGLTAISNNAGVDDFGLGLLLKHRQIATMIASYV
GENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVADGKETREIKGRHYVLEESLTADFALVRAWK
ADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGTFEKRIEQRTVKAAK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=238, Percent_Identity=57.1428571428571, Blast_Score=277, Evalue=5e-75,
Organism=Homo sapiens, GI11545841, Length=237, Percent_Identity=52.7426160337553, Blast_Score=239, Evalue=1e-63,
Organism=Escherichia coli, GI1788551, Length=208, Percent_Identity=45.6730769230769, Blast_Score=192, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=52.2633744855967, Blast_Score=258, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21358325, Length=248, Percent_Identity=50.8064516129032, Blast_Score=245, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24655794, Length=248, Percent_Identity=50.8064516129032, Blast_Score=245, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25094; Mature: 24963

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLNKVVSSYEEALNGLSNDMTIMVGGFGLCGIPEGLINQMVKMGVNGLTAISNNAGVD
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCC
DFGLGLLLKHRQIATMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVADGKETREIKGRHYVLEESLTADFALVRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCC
MATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGTFEKRIEQRTVKAAK
EECCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGLNKVVSSYEEALNGLSNDMTIMVGGFGLCGIPEGLINQMVKMGVNGLTAISNNAGVD
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCC
DFGLGLLLKHRQIATMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVADGKETREIKGRHYVLEESLTADFALVRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCC
MATAGKITVVEAEFIVEPGELDPDHIHTPGIYVDRVIQGTFEKRIEQRTVKAAK
EECCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]