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The map label for this gene is tesB [H]

Identifier: 160876071

GI number: 160876071

Start: 3516441

End: 3517307

Strand: Reverse

Name: tesB [H]

Synonym: Sbal195_2961

Alternate gene names: 160876071

Gene position: 3517307-3516441 (Counterclockwise)

Preceding gene: 160876072

Following gene: 160876070

Centisome position: 65.78

GC content: 49.25

Gene sequence:

>867_bases
ATGAGTCAGGTATTAGACGATCTTTTATCATTACTTTCCCTTGAGCAAATTGAAATCGGCCTCTTTCGTGGTCAGAGCCA
AGATCTGGGATTTGGGCATGTGTTCGGTGGTCAAGTGATGGGGCAAGCGCTGAGCGCCGCTAAACAAACCGTCCCCGCTG
AGCGTAAGGTCCACTCATTACACTCCTACTTTTTACGTGCCGGTGACGAGAAGTTACCGATTGTGTATGAAGTCGAAAAT
ATGCGAGATGGCGGCAGTTTTAGTGCCCGCCGCGTGAGTGCAATCCAAAAAGGTCGACCGATTTTCCACATGACCTGTTC
CTTCCAAGAACCTGAAGAAGGATTTAGTCATCAAGCGATGATGCCGCAAGTACCTGGACCAGAAGGTTTATTGAATCAGC
AGGAATTAGCGCTGACTATGCGGGATAAAGTGCCGCCGAGCATACTCGAAAAGTTTATGGCCGATGCGCCCATTGAGATG
CGACTGGTTAATCCATTACATCCCTTTGCGCCTAAAGAAACTGAGCCGTACCGTCATGTGTGGATGAGGGCCAATGGTCC
CATGCCAAATGACGCCCATATTCATGAATATTTACTCGCCTATGCCTCGGACTTTAACTTTCTCGTGACAGCGGCTCAGC
CCCACGGCGTGTCGTTTTTAAGTCCTGGAGTGCGCATGGCGACGATAGATCATGCGATGTGGTTCCATCGCCCGATTAAT
ATGGGAGAGTGGTTGCTTTACAGTATTGATAGCCCCAATGCCAGCGGTGGCAGAGGTTACGTCAGAGGGCAGTTTTTCAA
TCAACAAGGTGAATTAGTGGCTTCTTCTACCCAAGAAGGCCTGATCCGCATGGTAAAAGGACGTTAA

Upstream 100 bases:

>100_bases
GAGTGATGATTTCATTGTGAATAATCGATAGAAGACTGGTCAGCTTAAGGCGAACTGAGTTACCCTTTAGCATTAATGGC
TAATTATGCAGTAGGATCCC

Downstream 100 bases:

>100_bases
TATGTATCTGAAAATAAAGTCGTTTGTATTGTTCTCGCTCATGGCTATTCTACTCAATGGCTGCGTGACGGTGAAACCTG
AACCCCCGATTATTATCAAT

Product: acyl-CoA thioesterase II

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSQVLDDLLSLLSLEQIEIGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVPAERKVHSLHSYFLRAGDEKLPIVYEVEN
MRDGGSFSARRVSAIQKGRPIFHMTCSFQEPEEGFSHQAMMPQVPGPEGLLNQQELALTMRDKVPPSILEKFMADAPIEM
RLVNPLHPFAPKETEPYRHVWMRANGPMPNDAHIHEYLLAYASDFNFLVTAAQPHGVSFLSPGVRMATIDHAMWFHRPIN
MGEWLLYSIDSPNASGGRGYVRGQFFNQQGELVASSTQEGLIRMVKGR

Sequences:

>Translated_288_residues
MSQVLDDLLSLLSLEQIEIGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVPAERKVHSLHSYFLRAGDEKLPIVYEVEN
MRDGGSFSARRVSAIQKGRPIFHMTCSFQEPEEGFSHQAMMPQVPGPEGLLNQQELALTMRDKVPPSILEKFMADAPIEM
RLVNPLHPFAPKETEPYRHVWMRANGPMPNDAHIHEYLLAYASDFNFLVTAAQPHGVSFLSPGVRMATIDHAMWFHRPIN
MGEWLLYSIDSPNASGGRGYVRGQFFNQQGELVASSTQEGLIRMVKGR
>Mature_287_residues
SQVLDDLLSLLSLEQIEIGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVPAERKVHSLHSYFLRAGDEKLPIVYEVENM
RDGGSFSARRVSAIQKGRPIFHMTCSFQEPEEGFSHQAMMPQVPGPEGLLNQQELALTMRDKVPPSILEKFMADAPIEMR
LVNPLHPFAPKETEPYRHVWMRANGPMPNDAHIHEYLLAYASDFNFLVTAAQPHGVSFLSPGVRMATIDHAMWFHRPINM
GEWLLYSIDSPNASGGRGYVRGQFFNQQGELVASSTQEGLIRMVKGR

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=289, Percent_Identity=41.8685121107266, Blast_Score=205, Evalue=4e-53,
Organism=Escherichia coli, GI1786657, Length=283, Percent_Identity=60.0706713780919, Blast_Score=354, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI71988741, Length=293, Percent_Identity=33.7883959044369, Blast_Score=180, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17531889, Length=272, Percent_Identity=37.1323529411765, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI115532456, Length=272, Percent_Identity=37.1323529411765, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17531885, Length=272, Percent_Identity=37.1323529411765, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17558508, Length=306, Percent_Identity=34.9673202614379, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71982224, Length=277, Percent_Identity=29.2418772563177, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI212645202, Length=274, Percent_Identity=29.9270072992701, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6322480, Length=328, Percent_Identity=24.6951219512195, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32190; Mature: 32059

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVLDDLLSLLSLEQIEIGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVPAERKVHSL
CHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HSYFLRAGDEKLPIVYEVENMRDGGSFSARRVSAIQKGRPIFHMTCSFQEPEEGFSHQAM
HHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHCCCCCCC
MPQVPGPEGLLNQQELALTMRDKVPPSILEKFMADAPIEMRLVNPLHPFAPKETEPYRHV
CCCCCCCCCCCCCHHHEEEHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEE
WMRANGPMPNDAHIHEYLLAYASDFNFLVTAAQPHGVSFLSPGVRMATIDHAMWFHRPIN
EEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHCCCCC
MGEWLLYSIDSPNASGGRGYVRGQFFNQQGELVASSTQEGLIRMVKGR
CCCEEEEEECCCCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHHCCC
>Mature Secondary Structure 
SQVLDDLLSLLSLEQIEIGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVPAERKVHSL
HHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HSYFLRAGDEKLPIVYEVENMRDGGSFSARRVSAIQKGRPIFHMTCSFQEPEEGFSHQAM
HHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHCCCCCCC
MPQVPGPEGLLNQQELALTMRDKVPPSILEKFMADAPIEMRLVNPLHPFAPKETEPYRHV
CCCCCCCCCCCCCHHHEEEHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEE
WMRANGPMPNDAHIHEYLLAYASDFNFLVTAAQPHGVSFLSPGVRMATIDHAMWFHRPIN
EEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHCCCCC
MGEWLLYSIDSPNASGGRGYVRGQFFNQQGELVASSTQEGLIRMVKGR
CCCEEEEEECCCCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]