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The map label for this gene is hlyB [H]

Identifier: 160875937

GI number: 160875937

Start: 3363893

End: 3365632

Strand: Reverse

Name: hlyB [H]

Synonym: Sbal195_2826

Alternate gene names: 160875937

Gene position: 3365632-3363893 (Counterclockwise)

Preceding gene: 160875938

Following gene: 160875936

Centisome position: 62.94

GC content: 46.84

Gene sequence:

>1740_bases
ATGAAAACAAAAACCATGATGAGTGTGGTATTTTCGACCATAGTCGCGAGTGCCGTCATTTCTGCGGCACTGAGCTTCAA
TGTTAAGTCTAAAATCGATCTCTTTAATGATGCCGCCAGCATCCGATATCAGTCCTATCAACTTGCCGATGAATTAAGGC
AAGGCTCCGATGACTTAACACGTCTCGCCCGTACCTACGCCGTTACAGGCGATGAAAAATACGAAAAAATGTATATGGAT
ATTTTGGCTATCCGTAATGGTGAGAAACCCAGACCCGAAAAATATCATCAGATTTATTGGGATTTGGTACTGAGTTATGG
CGATAAGCCAAAGCCAGACGGCGCGAGAGTTGCTATAAAAGAGCAAATGAAGTCCCTTGGTTTTTCCGATGAAGAATTTC
GTTACCTCGAACAAGCCCAAAAAAACTCAGATGCGTTAGTCGCCCTCGAAGTGAAAGCCATGAATGCCGTCAAAGGTATC
TTTATGGACCCCAACACCCAAACCTATACGATCAAAGGCGAGCCTAACTTAACCATGGCGAGGGAGTTATTGCATAGCGA
CCAATACCATAGAGAAAAAGCCAAGATCATGCAGCCGATTGATGAGTTCTTTACGGCGTTGGATAAACGTACCGATGGTG
AAGTTAATGGTCGTCTCGACTCCTTACATGCGGCATTAAACTGGTCTCAGTTCGTGTTATTTATCGTGATTTTAGCGGCC
GTTGGTGGATTTATTATCGTTAAGAGTCGGATTGTGACTCCCTTAGTGCAGACCTGTAGTGAGTTGCTCGACATTCAGCG
CTCTAAAAACCTTGCGCGGCGGATCTCTGTCACCACTCAGGGAGAGATTGGCGAAATCGTTAATCAAATCAACTTGTTTA
TCTCTTCCCTTGCCAGTTCCTTATCGACAACGGATGGTATTGCAAAAGAGGTCGCTGATTTAGCGAAGCAAACCAAGGCA
TCAATCCAAGTTTCGCGTGAAAGCTCAAATCGGGTGGCGAGAGAACTGGATGCCAGCGCCAGTGCGATGGAAGAAATGAC
CACGACGTTAGTGCATGTGAGTGAGAGCACGTCGAACGCTGAAAGCCGCGCCGCTGAAAATGAAGCGCATGTCACAGTGG
GTAAACAGACGGTATCGGAAGCGTTGAAAGCCATGTCGGTATTGGAAACTGAGTTTACCAATACTCAAGACTCTATGTCG
CATTTAGTGAACGAAAGCACCCAAGTCAGTAATGTGTTGAGTGTAATTAAGGCGATTGCAGAGCAGACGAATTTGCTGGC
ACTGAATGCCGCGATTGAAGCCGCAAGGGCCGGTGAGCAAGGGCGAGGCTTCGCTGTGGTGGCCGATGAGGTTCGATCAC
TAGCCCAGCGTACCCAAGATTCCACTAAGGAAATCGACGATATTGTCGCAAGCCTTCAAAGTCGTACGAATCAAGTGGGC
ACATCTGTGACTCAAGCCGCGACGCTTATGCAAAAGGCGGGGGTAGAGCTGCAACGTATCGTGGCTGTATTTGAGGATAT
TCGTCACAGTACGGAAGCGATTCATGGGATCAATACTCAGGTTGCCGCTTCAACTGAGGAACAGTCCTTGGTTTCTAAAG
AAATCGCTTCGAGTATGATGGTGATCCGCGATAATTCCCGTGAAGTATCACAGATTATCGAGCAGATAGAATCGACCTCT
ATTAGCCTAGATAATCAATCTCAGATACTGCGCACTAAGGCGGGGGAATATCAGTTTTAG

Upstream 100 bases:

>100_bases
GCAAATCAAATGATTATTTTCATTGATTGTCCCACTTTTACCGATGTTTTCTGATTTTCCTTCTAGACTTAAAGCTGTTC
TTCCGTCTATTGGGGTAAGT

Downstream 100 bases:

>100_bases
ATGAGATGTGGTTGATTTACGAACGAAGGCCACTCAAGACATGGACGTCAATCCTTCCTCTTCGAATCCTCTCCTGAACA
TATTTTCTGCTTCGACACTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MKTKTMMSVVFSTIVASAVISAALSFNVKSKIDLFNDAASIRYQSYQLADELRQGSDDLTRLARTYAVTGDEKYEKMYMD
ILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIKEQMKSLGFSDEEFRYLEQAQKNSDALVALEVKAMNAVKGI
FMDPNTQTYTIKGEPNLTMARELLHSDQYHREKAKIMQPIDEFFTALDKRTDGEVNGRLDSLHAALNWSQFVLFIVILAA
VGGFIIVKSRIVTPLVQTCSELLDIQRSKNLARRISVTTQGEIGEIVNQINLFISSLASSLSTTDGIAKEVADLAKQTKA
SIQVSRESSNRVARELDASASAMEEMTTTLVHVSESTSNAESRAAENEAHVTVGKQTVSEALKAMSVLETEFTNTQDSMS
HLVNESTQVSNVLSVIKAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQSRTNQVG
TSVTQAATLMQKAGVELQRIVAVFEDIRHSTEAIHGINTQVAASTEEQSLVSKEIASSMMVIRDNSREVSQIIEQIESTS
ISLDNQSQILRTKAGEYQF

Sequences:

>Translated_579_residues
MKTKTMMSVVFSTIVASAVISAALSFNVKSKIDLFNDAASIRYQSYQLADELRQGSDDLTRLARTYAVTGDEKYEKMYMD
ILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIKEQMKSLGFSDEEFRYLEQAQKNSDALVALEVKAMNAVKGI
FMDPNTQTYTIKGEPNLTMARELLHSDQYHREKAKIMQPIDEFFTALDKRTDGEVNGRLDSLHAALNWSQFVLFIVILAA
VGGFIIVKSRIVTPLVQTCSELLDIQRSKNLARRISVTTQGEIGEIVNQINLFISSLASSLSTTDGIAKEVADLAKQTKA
SIQVSRESSNRVARELDASASAMEEMTTTLVHVSESTSNAESRAAENEAHVTVGKQTVSEALKAMSVLETEFTNTQDSMS
HLVNESTQVSNVLSVIKAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQSRTNQVG
TSVTQAATLMQKAGVELQRIVAVFEDIRHSTEAIHGINTQVAASTEEQSLVSKEIASSMMVIRDNSREVSQIIEQIESTS
ISLDNQSQILRTKAGEYQF
>Mature_579_residues
MKTKTMMSVVFSTIVASAVISAALSFNVKSKIDLFNDAASIRYQSYQLADELRQGSDDLTRLARTYAVTGDEKYEKMYMD
ILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIKEQMKSLGFSDEEFRYLEQAQKNSDALVALEVKAMNAVKGI
FMDPNTQTYTIKGEPNLTMARELLHSDQYHREKAKIMQPIDEFFTALDKRTDGEVNGRLDSLHAALNWSQFVLFIVILAA
VGGFIIVKSRIVTPLVQTCSELLDIQRSKNLARRISVTTQGEIGEIVNQINLFISSLASSLSTTDGIAKEVADLAKQTKA
SIQVSRESSNRVARELDASASAMEEMTTTLVHVSESTSNAESRAAENEAHVTVGKQTVSEALKAMSVLETEFTNTQDSMS
HLVNESTQVSNVLSVIKAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQSRTNQVG
TSVTQAATLMQKAGVELQRIVAVFEDIRHSTEAIHGINTQVAASTEEQSLVSKEIASSMMVIRDNSREVSQIIEQIESTS
ISLDNQSQILRTKAGEYQF

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=411, Percent_Identity=26.7639902676399, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI2367378, Length=370, Percent_Identity=27.5675675675676, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788195, Length=299, Percent_Identity=29.7658862876254, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788194, Length=364, Percent_Identity=29.9450549450549, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1789453, Length=333, Percent_Identity=26.1261261261261, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63787; Mature: 63787

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKTMMSVVFSTIVASAVISAALSFNVKSKIDLFNDAASIRYQSYQLADELRQGSDDLT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
RLARTYAVTGDEKYEKMYMDILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIK
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
EQMKSLGFSDEEFRYLEQAQKNSDALVALEVKAMNAVKGIFMDPNTQTYTIKGEPNLTMA
HHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCEECCCCEEEEEECCCCHHHH
RELLHSDQYHREKAKIMQPIDEFFTALDKRTDGEVNGRLDSLHAALNWSQFVLFIVILAA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VGGFIIVKSRIVTPLVQTCSELLDIQRSKNLARRISVTTQGEIGEIVNQINLFISSLASS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LSTTDGIAKEVADLAKQTKASIQVSRESSNRVARELDASASAMEEMTTTLVHVSESTSNA
HHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ESRAAENEAHVTVGKQTVSEALKAMSVLETEFTNTQDSMSHLVNESTQVSNVLSVIKAIA
HHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHH
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQSRTNQVG
HHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
TSVTQAATLMQKAGVELQRIVAVFEDIRHSTEAIHGINTQVAASTEEQSLVSKEIASSMM
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHEE
VIRDNSREVSQIIEQIESTSISLDNQSQILRTKAGEYQF
EEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTKTMMSVVFSTIVASAVISAALSFNVKSKIDLFNDAASIRYQSYQLADELRQGSDDLT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
RLARTYAVTGDEKYEKMYMDILAIRNGEKPRPEKYHQIYWDLVLSYGDKPKPDGARVAIK
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
EQMKSLGFSDEEFRYLEQAQKNSDALVALEVKAMNAVKGIFMDPNTQTYTIKGEPNLTMA
HHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCEECCCCEEEEEECCCCHHHH
RELLHSDQYHREKAKIMQPIDEFFTALDKRTDGEVNGRLDSLHAALNWSQFVLFIVILAA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VGGFIIVKSRIVTPLVQTCSELLDIQRSKNLARRISVTTQGEIGEIVNQINLFISSLASS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LSTTDGIAKEVADLAKQTKASIQVSRESSNRVARELDASASAMEEMTTTLVHVSESTSNA
HHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ESRAAENEAHVTVGKQTVSEALKAMSVLETEFTNTQDSMSHLVNESTQVSNVLSVIKAIA
HHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHH
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQDSTKEIDDIVASLQSRTNQVG
HHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
TSVTQAATLMQKAGVELQRIVAVFEDIRHSTEAIHGINTQVAASTEEQSLVSKEIASSMM
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHEE
VIRDNSREVSQIIEQIESTSISLDNQSQILRTKAGEYQF
EEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]