Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 160875893

GI number: 160875893

Start: 3312868

End: 3313530

Strand: Reverse

Name: lepB [H]

Synonym: Sbal195_2782

Alternate gene names: 160875893

Gene position: 3313530-3312868 (Counterclockwise)

Preceding gene: 160875894

Following gene: 160875889

Centisome position: 61.97

GC content: 48.57

Gene sequence:

>663_bases
ATGTTCAAAGGAATAACAAAACTACTTAAGGATAACCGCTCCTTTTTTCTGTTTATCAGTTTAATGTTAGTGTTCAGGAG
CGCTGTGGCTGATTGGAATACAGTGCCATCGGGTTCTATGCTGCCGACTATCGTCGAGGGCGATCGCATTCTGGTGAACA
AGATGGCCTACGATCTTAGGGTGCCATTTACCCATATCGCCTTAGTCAAACTGGCGGATCCCGCCCGCGGTGATATCGTG
GTGTTCGATTCGAAAAAGGCCGATAAAAAACTCATTAAGCGGGTGATTGCTGTGCCAGGCGATACTGTGATGATGCGGGA
TAATCGTTTGTATTTGAATGGCGAACCTCTTGGCTACGCATCCCAAGCATTGAGTCCTTATGCTCCCGCTGATGTCACAG
AAATGCAGGAGAACTTACTCGGTATGGCCCACAGTATTCGCCTTAATCCTGTCCCCTCAAGGCTTGCCAATTTTGGACCT
GTCACTGTGCCAGACGCGCATTACCTAGCGCTGGGTGATAATCGAGATAACAGCGCTGATTCTCGGGTCATTGGCTTTGT
GCCACGCAATGAGATTGTTGGCCGTTCAAGCTCAGTGGTTTTCTCCCTTGACTATGATGATCATTACTTGCCTCGACCTG
AGCGTCTCATGCGCGAGTTTTAG

Upstream 100 bases:

>100_bases
ATCTGTGCTTAAGCTGGTAGCAACAGAACTTAGTGCAACGCAATGGGTCTATCTAACTGAGAACAGCGACTAGCTTATAC
ATGCCATAGAGAGGGAATAT

Downstream 100 bases:

>100_bases
CATGCGCGGATTCTAGTATTCGTGATGTTGCTCCATAAAGAAGGGCGCCGAATGAGGCGCCCTTTTGTTAGCTGGTTGAT
TCAAAATGCTTTACTTCAAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MFKGITKLLKDNRSFFLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLRVPFTHIALVKLADPARGDIV
VFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLGYASQALSPYAPADVTEMQENLLGMAHSIRLNPVPSRLANFGP
VTVPDAHYLALGDNRDNSADSRVIGFVPRNEIVGRSSSVVFSLDYDDHYLPRPERLMREF

Sequences:

>Translated_220_residues
MFKGITKLLKDNRSFFLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLRVPFTHIALVKLADPARGDIV
VFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLGYASQALSPYAPADVTEMQENLLGMAHSIRLNPVPSRLANFGP
VTVPDAHYLALGDNRDNSADSRVIGFVPRNEIVGRSSSVVFSLDYDDHYLPRPERLMREF
>Mature_220_residues
MFKGITKLLKDNRSFFLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLRVPFTHIALVKLADPARGDIV
VFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLGYASQALSPYAPADVTEMQENLLGMAHSIRLNPVPSRLANFGP
VTVPDAHYLALGDNRDNSADSRVIGFVPRNEIVGRSSSVVFSLDYDDHYLPRPERLMREF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=264, Percent_Identity=31.4393939393939, Blast_Score=111, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 24612; Mature: 24612

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGITKLLKDNRSFFLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEEHHHHEE
VPFTHIALVKLADPARGDIVVFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLGYA
CCHHHEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCHH
SQALSPYAPADVTEMQENLLGMAHSIRLNPVPSRLANFGPVTVPDAHYLALGDNRDNSAD
HHHCCCCCCCHHHHHHHHHHHHHHEEEECCCHHHHHCCCCCCCCCCEEEEECCCCCCCCC
SRVIGFVPRNEIVGRSSSVVFSLDYDDHYLPRPERLMREF
CEEEEEECCHHHCCCCCCEEEEECCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MFKGITKLLKDNRSFFLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEEHHHHEE
VPFTHIALVKLADPARGDIVVFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLGYA
CCHHHEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCHH
SQALSPYAPADVTEMQENLLGMAHSIRLNPVPSRLANFGPVTVPDAHYLALGDNRDNSAD
HHHCCCCCCCHHHHHHHHHHHHHHEEEECCCHHHHHCCCCCCCCCCEEEEECCCCCCCCC
SRVIGFVPRNEIVGRSSSVVFSLDYDDHYLPRPERLMREF
CEEEEEECCHHHCCCCCCEEEEECCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]