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The map label for this gene is uvrC [H]

Identifier: 160875788

GI number: 160875788

Start: 3174911

End: 3176740

Strand: Reverse

Name: uvrC [H]

Synonym: Sbal195_2676

Alternate gene names: 160875788

Gene position: 3176740-3174911 (Counterclockwise)

Preceding gene: 160875789

Following gene: 160875787

Centisome position: 59.41

GC content: 47.27

Gene sequence:

>1830_bases
ATGTCGAATGAATTTAACGCCCAAAGTTTTTTACGTACGGTTTCATCCTCCGCTGGGGTTTATCGCATGTATGACGTCAA
GAATGACGTCATTTATGTGGGTAAAGCCAAAGATCTCAAAAAACGGCTTACCTCGTATTTTCGTAAAAATCTCGCTAATG
TTAAGACCCAAGCCTTAGTCTCGCATATACACCATATTGATGTGACGCTGACCCACAGCGAAACCGATGCTCTGTTGCTT
GAGAATGATTACATCAAGCAATACATGCCCAAATACAATGTGTTATTGCGTGATGACAAATCTTATCCTTATATACTGCT
AAGCCAGCACGAACACCCAAGACTTGCCTATCATCGTGGTCCGCAGCGGGAAAAAGGCCACTATTTTGGCCCTTATCCTA
ACGGCGGCGCCGTGCGTGAAAGCCTGCATTTAATGCAGAAGCTGTTTCCAATTCGTCAATGTGACGACCTTTACTACAAG
TCTCGCTCACGGCCCTGTTTGCAATATCAAATTTCCCGTTGTAGCGCGCCCTGTGTGGGTAAAGTCAGCAACGCCGATTA
CGACGAGCAAGTGAAACTCGCCAGCCTGTTTTTAAAGGGCAAAGATCAGCAAGTGATCAGCGCCTTGGTTGACAAAATGG
AGCTTGCAGCCGAGCGACAAGCTTATGAGCAAGCTGCACGATTTCGCGATCAGATCATGGCGCTGCGTAAAGTCGCCGAA
CAACAGGAAGTATCGAATAATAAAGGCGATATGGATGTCATCGGTGTGCATTATTCGTCGGGCATCGCCTGTTTCCATTT
GCTGTTTATCCGCGAGGGTAAAATCTTTGGTAGTCGCAGCTATTATCCTTCCGTGCCCGCCCAAACCGATATGGACGAAG
TGCTGCGCTCTTTCATCCTGCAGTTTTATTTAAATGCGGATATTCAACGCACGATCCCAAAGGAAGTGGTGATTAGCCAC
AACTTTGAAGAATTACATGAACTCGAAGCGGCAATTTCAGAGGCGTTAGATAAAAAGTTTTCGATTAAGACCAATGTACG
CGCCGACAGGGCAAGCTTCTTACGGTTAGCCGTGACCAATGCGACGAATGCCGTGGTTACGCGCTTGTCCCATAAAAATA
CGGTCGAGCAGCGTTTTGTATTACTCGAAGAAATCCTTGAATTGAGTACGCCTATTCAACGGATGGAATGTTTTGATATC
AGTCATACCATGGGGGAGAGCACGGTTGCCTCCTGTGTGGTGTTCAATCGGGAAGGGCCGCATAAAGGCGAATATCGCCG
CTATAACATCGAGGGAATTACACCGGGCGATGATTACGCGGCAATGAAGCAAGCGGTGAGTCGACGCTTCGATAAGATTG
AGGCGGGCGGTAAAATCCCTGACATTCTGTTTATCGATGGTGGACTCGGGCAGTTGCGTATCGCCCAGAAGATAGTAGAT
GAAAAGTTTGTCCATTTAGATAAAGCACCGCAGCTCATTGGGGTGGCGAAAGGTGAGGGCCGTAAACCTGGGCTCGAAAC
CTTGATTTTAGGGGATACAGAAACCAGCTTTTCCCTCGAAGGTGATTCGCCTGCGTTGCACCTTATTCAACATATTCGCG
ATGAGTCCCATCGATTCGCGATAACAGGCCATCGTAATCGTCGCCAGAAAACCCGCAATACTTCCACATTGGAATCTATT
CCAGGAATTGGCCCTAAACGTCGTAAAGCTTTGTTGCAGCATTTAGGTGGCTTGCAAGAAGTGAAAGGAGCAAGTGTGGC
GGAATTAGTCAAAGTACCAGGGATCAGCATAGAAATGGCACAAACCATTCATGATGCATTGCGAGGGTGA

Upstream 100 bases:

>100_bases
AAAATGAATTGTGTTGGTCGATGACTTGAGTCGAGTAAGCGCGTAGGTTAAATACTGCTATGTTGTCTGTGTTAAGTCTG
CAAAATTGTGGGTGTAAATG

Downstream 100 bases:

>100_bases
TAAAATTAAGGCAAGATTGGCGCTGCTTTTGACTAACTGGTTTGATCATGCCGTTTAACTTACCTATAGCATTAACTCTT
TTCAGGCTTTTTTTACTGCC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MSNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALVSHIHHIDVTLTHSETDALLL
ENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRGPQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYK
SRSRPCLQYQISRCSAPCVGKVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAE
QQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFILQFYLNADIQRTIPKEVVISH
NFEELHELEAAISEALDKKFSIKTNVRADRASFLRLAVTNATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDI
SHTMGESTVASCVVFNREGPHKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVD
EKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESI
PGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMAQTIHDALRG

Sequences:

>Translated_609_residues
MSNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALVSHIHHIDVTLTHSETDALLL
ENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRGPQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYK
SRSRPCLQYQISRCSAPCVGKVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAE
QQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFILQFYLNADIQRTIPKEVVISH
NFEELHELEAAISEALDKKFSIKTNVRADRASFLRLAVTNATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDI
SHTMGESTVASCVVFNREGPHKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVD
EKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESI
PGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMAQTIHDALRG
>Mature_608_residues
SNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALVSHIHHIDVTLTHSETDALLLE
NDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRGPQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKS
RSRPCLQYQISRCSAPCVGKVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAEQ
QEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFILQFYLNADIQRTIPKEVVISHN
FEELHELEAAISEALDKKFSIKTNVRADRASFLRLAVTNATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDIS
HTMGESTVASCVVFNREGPHKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVDE
KFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESIP
GIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMAQTIHDALRG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=57.3770491803279, Blast_Score=728, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 68890; Mature: 68758

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALV
CCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRG
HHHHHEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCHHCCC
PQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRSRPCLQYQISRCSAPCVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
KVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAE
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFIL
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QFYLNADIQRTIPKEVVISHNFEELHELEAAISEALDKKFSIKTNVRADRASFLRLAVTN
HHHHCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHEEEEEECC
ATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDISHTMGESTVASCVVFNREGP
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHEEEECCCCC
HKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
EKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFA
HHHHHHCCCCCEEEECCCCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHCCCCEEE
ITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMA
EECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHCCCCCHHHH
QTIHDALRG
HHHHHHHCC
>Mature Secondary Structure 
SNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALV
CCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRG
HHHHHEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCHHCCC
PQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRSRPCLQYQISRCSAPCVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
KVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAE
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFIL
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QFYLNADIQRTIPKEVVISHNFEELHELEAAISEALDKKFSIKTNVRADRASFLRLAVTN
HHHHCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHEEEEEECC
ATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDISHTMGESTVASCVVFNREGP
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHEEEECCCCC
HKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVD
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
EKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFA
HHHHHHCCCCCEEEECCCCCCCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHCCCCEEE
ITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMA
EECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHCCCCCHHHH
QTIHDALRG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA