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The map label for this gene is uvrY [H]

Identifier: 160875789

GI number: 160875789

Start: 3176844

End: 3177488

Strand: Reverse

Name: uvrY [H]

Synonym: Sbal195_2677

Alternate gene names: 160875789

Gene position: 3177488-3176844 (Counterclockwise)

Preceding gene: 160875790

Following gene: 160875788

Centisome position: 59.42

GC content: 48.53

Gene sequence:

>645_bases
TTGATTTCGATATATTTGGTTGACGATCATGAGCTTGTGAGAACTGGGATCCGCCGCATCTTGGAAGATGAACGTGGGAT
CAAAGTGGTGGGCGAAGCCCCTGATGGTGAGACTGCGGTGCAGTGGGCTCGCCAAAACGAAGCCGATGTGATCTTAATGG
ACATGAATATGCCTGGGATGGGCGGACTGGAAGCCACTCGAAAAATTCTGCGTTATCAACCCCATGCTAAAATTATTGTG
TTGACTGTGCACACGGAAGATCCATTCCCGAGCAAGGTCATGCAGGCTGGCGCTTCGGGTTATTTGACGAAAGGGGCGAC
GCCGCCGGAAGTATTGCAGGCAATACGTCAGGTGTCTCGCGGCCAACGTTATTTATCCCCTGAAATTGCCCAACAGATGG
CGCTGAGTCAGTTTAATCCCGCCGATGAAAACCCGTTTAAGTCTCTGTCTGAACGTGAGTTACAAATCATGTTGATGATC
ACCAACGGCGAGAAGGTAAACGATATTTCTGAGCAGCTGAACTTAAGCCCTAAAACGGTTAACAGTTACCGCTATCGTTT
ATTTGCCAAACTGGGGATCAGTGGTGATGTTGAGCTAACGCGGTTAGCTATTCGCTATAAGATGTTGGATGCTGGCCATT
TTTAA

Upstream 100 bases:

>100_bases
AATGGGGTTGTTGGGCTAAATTAGCCTTATGAACTCGTTATCCGTCTGCTGTTTTGTTTAACGCGCGGATCGAGCTGTAA
ATTGTAAAAGGTGGGTTAAG

Downstream 100 bases:

>100_bases
TGGAAAATGAATTGTGTTGGTCGATGACTTGAGTCGAGTAAGCGCGTAGGTTAAATACTGCTATGTTGTCTGTGTTAAGT
CTGCAAAATTGTGGGTGTAA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGMGGLEATRKILRYQPHAKIIV
LTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSRGQRYLSPEIAQQMALSQFNPADENPFKSLSERELQIMLMI
TNGEKVNDISEQLNLSPKTVNSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF

Sequences:

>Translated_214_residues
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGMGGLEATRKILRYQPHAKIIV
LTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSRGQRYLSPEIAQQMALSQFNPADENPFKSLSERELQIMLMI
TNGEKVNDISEQLNLSPKTVNSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF
>Mature_214_residues
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGMGGLEATRKILRYQPHAKIIV
LTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSRGQRYLSPEIAQQMALSQFNPADENPFKSLSERELQIMLMI
TNGEKVNDISEQLNLSPKTVNSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=71.6981132075472, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=36.2745098039216, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=35.6435643564356, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=25.1207729468599, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=27.6699029126214, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24042; Mature: 24042

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGM
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCC
GGLEATRKILRYQPHAKIIVLTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSR
CCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
GQRYLSPEIAQQMALSQFNPADENPFKSLSERELQIMLMITNGEKVNDISEQLNLSPKTV
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCHH
NSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF
HHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGM
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCC
GGLEATRKILRYQPHAKIIVLTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSR
CCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
GQRYLSPEIAQQMALSQFNPADENPFKSLSERELQIMLMITNGEKVNDISEQLNLSPKTV
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCHH
NSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF
HHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]