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The map label for this gene is mdtA [H]

Identifier: 160875746

GI number: 160875746

Start: 3120600

End: 3121664

Strand: Direct

Name: mdtA [H]

Synonym: Sbal195_2634

Alternate gene names: 160875746

Gene position: 3120600-3121664 (Clockwise)

Preceding gene: 160875745

Following gene: 160875747

Centisome position: 58.36

GC content: 46.1

Gene sequence:

>1065_bases
ATGGAAAAGTCAAACATTGCTAAATTCGCCCTACCCCTGCTAATGATTTCAATGCTAGCAGCCTGTGGTAAGGAAGAAGT
GGCTAAAAAAGAAGAAAAATATGCCATTCCCGTCGAAACCACCACAGTGATGCAAGGAAACGTTTCATCTTTCTACAGCA
CAACAGCCACCTTAGAAGCACCTCAAGAAGCCAATGTCGTCAGCCGCATTTCTGGACTCATTGAATCACTAGCCGTTGAA
GAAGGTGACCGCGTGCAGAAGGGGCAAGTGCTCGCCGTTATCGATGCCAAAAGACAGCAATACGATTTAGACCGCTCAGA
AGCCGAAGTTAAAATCATTGAGCAGGAATTGAATCGTCTGAAGAAAATGGGCAACAAAGAATTTATCAGCGCTGATTCGA
TGGCCAAACTTGAATATAACTTGCAAGCCGCCATCGCTAAGAAAGATCTTGCCGAGCTACAAGTTAGAGAAAGCCGCGTA
CTGTCCCCTATTAGCGGTGTCGTCGCTAAACGTTATGTGAAAGCAGGCAACATGGCGAAGGAATTTGGCGACTTGTTTTA
TATCGTTAATCAAGATGAACTCCACGGTATAGTCCATCTGCCAGAGCAACAACTTGCCAGCTTAAAACTCGGCCAAGAAG
CACAAGTGTTCAGCAATCAACAAAGTAAAATTGCTATCCATGCCAAAGTGCTGCGGATAAGCCCGATTGTTGACCCACAA
AGCGGCACGTTTAAAGTGACATTAGCCGTACCGAATCAAGAGGCGCGCCTAAAAGCAGGGATGTTTACCCGTGTTGAGCT
TAAGTATGACACCCATGAAAACGTGATTACCGTTCCCTATAGCGCCCTGATTAATCAAGATAACAGGCAAGCTCTGTATG
TTATCGATGGCACTAGTGCTAATCGCCGTGAAGTCGAAATTGGCTACCGTGAAGGTGACTCTGTAGAAGTGATTGCAGGC
ATTAACCCAGGTGAACAAGTCGTGACCCGTGGCCAGCAAAACTTGAAAGACCAATCCTTAGTCGAAGTGATCACCCCACT
CGATCTTGCTTCCGCTAAGAACTGA

Upstream 100 bases:

>100_bases
CTTAAATATAGCTTAACTATATGAAATTAAGCTATATTTAATGTTGGCACGGTTTCTGCTATCAACTGGCATCACAATAA
AGACAACAGGTAACACACTT

Downstream 100 bases:

>100_bases
TAGGAGCCTTTCATGTCAATTATCAGCACTTCCGTTAAACGGCCAGTCACGGTATGGATGTTCATGCTGGCGGTGATTTT
ATTCGGTATGGTGGGATTTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRISGLIESLAVE
EGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRV
LSPISGVVAKRYVKAGNMAKEFGDLFYIVNQDELHGIVHLPEQQLASLKLGQEAQVFSNQQSKIAIHAKVLRISPIVDPQ
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTSANRREVEIGYREGDSVEVIAG
INPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN

Sequences:

>Translated_354_residues
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRISGLIESLAVE
EGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRV
LSPISGVVAKRYVKAGNMAKEFGDLFYIVNQDELHGIVHLPEQQLASLKLGQEAQVFSNQQSKIAIHAKVLRISPIVDPQ
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTSANRREVEIGYREGDSVEVIAG
INPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
>Mature_354_residues
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRISGLIESLAVE
EGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRV
LSPISGVVAKRYVKAGNMAKEFGDLFYIVNQDELHGIVHLPEQQLASLKLGQEAQVFSNQQSKIAIHAKVLRISPIVDPQ
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTSANRREVEIGYREGDSVEVIAG
INPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=332, Percent_Identity=25.6024096385542, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI87081796, Length=330, Percent_Identity=23.9393939393939, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39086; Mature: 39086

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEA
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEECCCEEEEEEECCHHHHHCCEEEECC
PQEANVVSRISGLIESLAVEEGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHH
KKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRVLSPISGVVAKRYVKAGNMAK
HHCCCCCEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
EFGDLFYIVNQDELHGIVHLPEQQLASLKLGQEAQVFSNQQSKIAIHAKVLRISPIVDPQ
HHCCEEEEECCCCCCCEEECCHHHHHHHCCCCHHHHHCCCCCEEEEEEEEEEEECCCCCC
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTSA
CCEEEEEEEECCCHHHHHCCCEEEEEEEECCCCCEEEECHHHHHCCCCCEEEEEEECCCC
NRREVEIGYREGDSVEVIAGINPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
CCEEEEEEECCCCCEEEEECCCCCHHHHHCCHHCCCHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEA
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEECCCEEEEEEECCHHHHHCCEEEECC
PQEANVVSRISGLIESLAVEEGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHH
KKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRVLSPISGVVAKRYVKAGNMAK
HHCCCCCEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
EFGDLFYIVNQDELHGIVHLPEQQLASLKLGQEAQVFSNQQSKIAIHAKVLRISPIVDPQ
HHCCEEEEECCCCCCCEEECCHHHHHHHCCCCHHHHHCCCCCEEEEEEEEEEEECCCCCC
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTSA
CCEEEEEEEECCCHHHHHCCCEEEEEEEECCCCCEEEECHHHHHCCCCCEEEEEEECCCC
NRREVEIGYREGDSVEVIAGINPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
CCEEEEEEECCCCCEEEEECCCCCHHHHHCCHHCCCHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]