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The map label for this gene is gltA [H]

Identifier: 160875745

GI number: 160875745

Start: 3119015

End: 3120301

Strand: Direct

Name: gltA [H]

Synonym: Sbal195_2633

Alternate gene names: 160875745

Gene position: 3119015-3120301 (Clockwise)

Preceding gene: 160875734

Following gene: 160875746

Centisome position: 58.33

GC content: 45.84

Gene sequence:

>1287_bases
ATGGCTGATTTAAAAGCCAAATTAGAATTACCAGGGAACGACTCGATAGAATTGCCAGTAAAGCAGGGAACCGCTGGTTT
TGACGTAATCGACATCAGTAAACTTGGCAGCAAAGGTTACTTCACTTTTGATCCAGGTTTTCTTGCGACTGCCTCCTGTG
AATCTGCAATTACCTATATTGATGGTGATCTGGGTATATTGTTACACCGTGGCTATCCAATCGATCAACTCGCCGTTGAC
TCCGATTACCTAGACCTGTGTTATCTGCTGCTTTACGGTGAACTGCCGACGAAAGCGCAATATACTGAGTTTGTACATAC
AGTTAAAACCCACACTATGGTTCACGAGCAGCTAGCCTTCTTCTTTAGAGGTTTCCGTCGTGATGCTCATCCTATGGCCA
TGTTATGTGGTGTGACGGGTGCATTATCTGCATTTTACCAAGACTCTCTGGATGTTAACGATCCACGTCACCGCGAAATC
GCCGCTTATCGCTTAGTCTCAAAAATGCCTACGATAGCAGCCATGTGCTACAAGTATTCTTCAGGCCAGCCATTCGTGTA
CCCACGTAATGACTTAAGCTATGCGGGCAACTTCTTAAGCATGATGTTTGCTGTGCCATGCGAAGAATACATCGTTAACC
CTATCGTTGAACGTGCAATGGACAGGATCTTCATTTTACATGCTGATCATGAACAAAATGCATCGACTTCAACCGTACGT
TTAGCCGGTTCTTCAGGTGCTAACCCATTTGCGTGTATCGCAGCGGGTATCGCGTCTCTTTGGGGTCCTGCACACGGCGG
CGCTAACGAAGCCTGTTTGCAAATGTTAGAAGAAATCGGTTCAGTTGACCGCATTCCTGAATTCATTGAACGTGCTAAAG
ATAAGAACGATCCATTCCGTCTGATGGGCTTTGGACACCGTGTTTACAAAAACTTTGACCCACGTGCCAAAGTTATGCGT
GAAACCTGTCACGAAGTGCTGAAAGAACTGAAAGTTAAGGATCCACTATTGGATGTGGCAATGGAGCTTGAGCGCATTGC
GCTTGAAGACGAATACTTCATTTCTAAGAAGCTGTATCCAAACGTCGACTTCTACTCTGGCATCATCATGAAAGCCATTG
GTATTCCAACCAGTATGTTCACTGTGCTGTTCGCACTGGCACGTACTGTAGGCTGGATTGCACACTGGAAAGAAATGTTA
GATCAACCAGGCCACAAAATCAGCCGTCCACGTCAGTTATACACTGGCGAAACTGCGCGTGATTTCGTCGCACAAGACAA
ACGCTAA

Upstream 100 bases:

>100_bases
AACGCTTATTTAAATTGAAATGTGATCTAGAATGGCTGTAAAGTAATGGCGGTTTGACATGCCGCACTCACAGATAAGAA
CTAAGTAAGGAGAACGGGGT

Downstream 100 bases:

>100_bases
GTCCCACGACTTACGCACTAAAAAGCGCCTGAGGGCGCTTTTTTCATATCAAACAATCCCCTTTGACACTCCCTTTGTTA
GACAAAATACATTGTTGCAA

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MADLKAKLELPGNDSIELPVKQGTAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYIDGDLGILLHRGYPIDQLAVD
SDYLDLCYLLLYGELPTKAQYTEFVHTVKTHTMVHEQLAFFFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREI
AAYRLVSKMPTIAAMCYKYSSGQPFVYPRNDLSYAGNFLSMMFAVPCEEYIVNPIVERAMDRIFILHADHEQNASTSTVR
LAGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIERAKDKNDPFRLMGFGHRVYKNFDPRAKVMR
ETCHEVLKELKVKDPLLDVAMELERIALEDEYFISKKLYPNVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEML
DQPGHKISRPRQLYTGETARDFVAQDKR

Sequences:

>Translated_428_residues
MADLKAKLELPGNDSIELPVKQGTAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYIDGDLGILLHRGYPIDQLAVD
SDYLDLCYLLLYGELPTKAQYTEFVHTVKTHTMVHEQLAFFFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREI
AAYRLVSKMPTIAAMCYKYSSGQPFVYPRNDLSYAGNFLSMMFAVPCEEYIVNPIVERAMDRIFILHADHEQNASTSTVR
LAGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIERAKDKNDPFRLMGFGHRVYKNFDPRAKVMR
ETCHEVLKELKVKDPLLDVAMELERIALEDEYFISKKLYPNVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEML
DQPGHKISRPRQLYTGETARDFVAQDKR
>Mature_427_residues
ADLKAKLELPGNDSIELPVKQGTAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYIDGDLGILLHRGYPIDQLAVDS
DYLDLCYLLLYGELPTKAQYTEFVHTVKTHTMVHEQLAFFFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREIA
AYRLVSKMPTIAAMCYKYSSGQPFVYPRNDLSYAGNFLSMMFAVPCEEYIVNPIVERAMDRIFILHADHEQNASTSTVRL
AGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIERAKDKNDPFRLMGFGHRVYKNFDPRAKVMRE
TCHEVLKELKVKDPLLDVAMELERIALEDEYFISKKLYPNVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEMLD
QPGHKISRPRQLYTGETARDFVAQDKR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=366, Percent_Identity=26.775956284153, Blast_Score=110, Evalue=4e-24,
Organism=Escherichia coli, GI1786939, Length=428, Percent_Identity=77.1028037383178, Blast_Score=698, Evalue=0.0,
Organism=Escherichia coli, GI1786527, Length=373, Percent_Identity=31.3672922252011, Blast_Score=160, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17555174, Length=367, Percent_Identity=26.7029972752044, Blast_Score=105, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6319850, Length=374, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324328, Length=372, Percent_Identity=26.8817204301075, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325257, Length=383, Percent_Identity=25.3263707571802, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640126, Length=352, Percent_Identity=27.8409090909091, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24640124, Length=352, Percent_Identity=27.8409090909091, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21356863, Length=357, Percent_Identity=26.0504201680672, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48036; Mature: 47905

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLKAKLELPGNDSIELPVKQGTAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYI
CCCCCEEEECCCCCCEEEECCCCCCCCCEEEHHHCCCCCEEEECCCCEECCCHHCCCEEE
DGDLGILLHRGYPIDQLAVDSDYLDLCYLLLYGELPTKAQYTEFVHTVKTHTMVHEQLAF
CCCEEEEEECCCCHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREIAAYRLVSKMPTIAAMCYKYS
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCC
SGQPFVYPRNDLSYAGNFLSMMFAVPCEEYIVNPIVERAMDRIFILHADHEQNASTSTVR
CCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIERAKDKNDPFR
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEE
LMGFGHRVYKNFDPRAKVMRETCHEVLKELKVKDPLLDVAMELERIALEDEYFISKKLYP
EEECCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHCCCC
NVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEMLDQPGHKISRPRQLYTGETAR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHH
DFVAQDKR
HHHHCCCC
>Mature Secondary Structure 
ADLKAKLELPGNDSIELPVKQGTAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYI
CCCCEEEECCCCCCEEEECCCCCCCCCEEEHHHCCCCCEEEECCCCEECCCHHCCCEEE
DGDLGILLHRGYPIDQLAVDSDYLDLCYLLLYGELPTKAQYTEFVHTVKTHTMVHEQLAF
CCCEEEEEECCCCHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREIAAYRLVSKMPTIAAMCYKYS
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCC
SGQPFVYPRNDLSYAGNFLSMMFAVPCEEYIVNPIVERAMDRIFILHADHEQNASTSTVR
CCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIERAKDKNDPFR
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEE
LMGFGHRVYKNFDPRAKVMRETCHEVLKELKVKDPLLDVAMELERIALEDEYFISKKLYP
EEECCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHCCCC
NVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEMLDQPGHKISRPRQLYTGETAR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHH
DFVAQDKR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]