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The map label for this gene is cheA [H]

Identifier: 160875476

GI number: 160875476

Start: 2785890

End: 2788064

Strand: Reverse

Name: cheA [H]

Synonym: Sbal195_2364

Alternate gene names: 160875476

Gene position: 2788064-2785890 (Counterclockwise)

Preceding gene: 160875477

Following gene: 160875475

Centisome position: 52.14

GC content: 46.76

Gene sequence:

>2175_bases
ATGTCCATCAATATGGCCGAGTTCCATCAGGTCTTTTTTGAAGAAAGTCATGAACATCTTGAAAATATGGAACAATTGCT
ATTGGCATTGGACCTTGCTTCTCCCGATCCTGAAGAACTGAACACTATTTTCCGTGCCGCCCACTCGATTAAAGGTGGCA
GCGGTATTTTTGGTTTTACCGCACTGACCAGTGTCACCCATGTGATGGAAAACCTGCTGGATAAGACCCGCAAAGGCAAC
TTCCAACTCACCTCATCGATTATCGATTTACTGCTGAGTACCGTTGATACGCTATCTCATATATTGAGCCTGTATCGCGA
AGAAGAACAGATTGATTGGCAGGAGGTGGAGTACAGTAAAAGTCAGCTGGTCGCAGCGTTAAATGGCGAGTCGTTTAGCT
CATCGGTTGCTGTACGCAATGGCACAGATGCTGCTAATGCTCCGATTTCTCCCATTATCCAAGCCGAGTCAGTGGAGAAG
TTGGAAGATCTGGGTTTTGGATTCTTTGAAGATGAAATGGATCGCGATATTGCCATTGAAGGTGAAGACTTTGGCTTTTT
TGAAGTGGCTTATCAAGCCGAAGAAATCAGCGCACAAAGTGTAGTAAATTATGTAAGCAATACTGATAAAGCGGCGGATC
CCTTTGATTTCACATCCGATGATGAATTAGGCTTTGGCTTTTTTGAGGCATTAACGCCGGAATCCTTCGCCAATGAAATC
GAGTTACTGAGCTCAAAGCCAGTAGCGCCTAAGGTAGTTAAACCCACCACAGTTGCCAATCAAGCTGAAGTCAACGCAGA
TAGCAGCCAAGCAAAACGCGGCATATTTAAAGAAAAAGAGAGCGTTACTGACGCCAAAGTGTCGCCTGCTGTAAGTGTTC
CCACGAGTGTTTCTGTAAACCCAGCCCCCCATTCAAATGCAACAAGTCCAAATGCGGCACTCAGTTCATCCGCTATACCA
AAAAATACGCCTTCAGAAGTGAAAGCTGCGGCTAAAAAACCTGCCGCGTCGGCTCAGGATGCCACCTTAAGGGTCGAAAC
CTCCAAAATCGATACCCTGGTCAATCTAGCGGGCGAGCTGGTGATCACTCAGTCCATGCTAACGCTTATCGGCAATGAAA
TGACGGGCGATTTAGGCGAGCGGCTTAAGACTGCGCTCAATGAATTGGAACGTAATACCCGTGAGATGCAAGAGGCGGTG
ATGTCGGTGCGTATGCTGCCGGTATCTTTTGTGTTTAACCGTTTCAATCGTTTGGTGAGGGATCTTTCTGAGCAACTGGG
TAAAAACGTCAATCTCGTGATTGAAGGTGGCAACACAGAAATTGATAAGGGCATGATTGAAAAGCTTGTCGATCCACTGA
CCCATTTAGTGCGCAATAGCTTAGATCACGGCATCGAAAAACCAGAGAAACGACTCGCAGCGGGTAAATCCGAAGTGGGC
GTATTGTCCCTAAAAGCCAGCCAAAGGGGTGGCAATATTGTTATCGCTGTGCATGATAATGGCGCGGGTTTAAACCGTGA
GCGCATTATTCAAAAGGCGCGAGAAAGTGGTTTGCAAGTGGCTGATAACAGTAGCGACAAGCAAATTTGGCAATTGATTT
TTGCCGCAGGATTTTCAACCGCGGTGGAAGTCACAGATGTGTCTGGCCGCGGTGTCGGTATGGATGTGGTGCGCCGCAAT
ATTGAAGCCTTAGGCGGACGCATTGATATTGAGTCCACTGAGGGTCAAGGTTCAACCTTTGAAATCCAATTGCCACTTAC
GCTGGCGATTGTCGATGGTATGACGGTTTCTGTGGGAAATCAGATCTACATTTTGCCCTTAGTGCACATCATTGAATCCA
TTCAGCCGCAAACTGAACAACTCAAATTTCTAGCCAAAGAAAGACTCTTAAAAGTACGTGAAGAGTACTTACCTCTACTT
AACCTTTATCAGCTGATGGAAATTGAGCCCAATGCTAAGAGCCCTGAAGAGGGCATAGTGGTATTGCTCGAAAGTAACCA
CAAGCGCTTTGGCCTGTGTGTTGATGCCTTAGTTGGCCAGCAGCAAGTCGTGATCAAGAGTCTTGAAAAACATTATCGTA
GGATCCCAGGAGTTTCCGGCGCCACCATCATGGGCGATGGCAGCGTCGCGTTGATCCTCGATGTCGAATCGCTCGCTCTG
CACATTAAAAATTAA

Upstream 100 bases:

>100_bases
AAGCGGCAGGTGCGACGGGATGGATGGTAAAACCCTTTGATCCTCAAAAGCTGTTGGCTATTACGGCAAAAGTGCTGGGT
TAACTGCAACGGGGTGCGCT

Downstream 100 bases:

>100_bases
GGAAATAGCCATGGAGAGTCGATCAACTATGACCGCCAAAGTGGAATACAACTCCCATGATGAGGTGGAGTTTTTGAGTT
TTATGCTGGGCGAAGAGCAC

Product: signal transduction histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MSINMAEFHQVFFEESHEHLENMEQLLLALDLASPDPEELNTIFRAAHSIKGGSGIFGFTALTSVTHVMENLLDKTRKGN
FQLTSSIIDLLLSTVDTLSHILSLYREEEQIDWQEVEYSKSQLVAALNGESFSSSVAVRNGTDAANAPISPIIQAESVEK
LEDLGFGFFEDEMDRDIAIEGEDFGFFEVAYQAEEISAQSVVNYVSNTDKAADPFDFTSDDELGFGFFEALTPESFANEI
ELLSSKPVAPKVVKPTTVANQAEVNADSSQAKRGIFKEKESVTDAKVSPAVSVPTSVSVNPAPHSNATSPNAALSSSAIP
KNTPSEVKAAAKKPAASAQDATLRVETSKIDTLVNLAGELVITQSMLTLIGNEMTGDLGERLKTALNELERNTREMQEAV
MSVRMLPVSFVFNRFNRLVRDLSEQLGKNVNLVIEGGNTEIDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRLAAGKSEVG
VLSLKASQRGGNIVIAVHDNGAGLNRERIIQKARESGLQVADNSSDKQIWQLIFAAGFSTAVEVTDVSGRGVGMDVVRRN
IEALGGRIDIESTEGQGSTFEIQLPLTLAIVDGMTVSVGNQIYILPLVHIIESIQPQTEQLKFLAKERLLKVREEYLPLL
NLYQLMEIEPNAKSPEEGIVVLLESNHKRFGLCVDALVGQQQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLAL
HIKN

Sequences:

>Translated_724_residues
MSINMAEFHQVFFEESHEHLENMEQLLLALDLASPDPEELNTIFRAAHSIKGGSGIFGFTALTSVTHVMENLLDKTRKGN
FQLTSSIIDLLLSTVDTLSHILSLYREEEQIDWQEVEYSKSQLVAALNGESFSSSVAVRNGTDAANAPISPIIQAESVEK
LEDLGFGFFEDEMDRDIAIEGEDFGFFEVAYQAEEISAQSVVNYVSNTDKAADPFDFTSDDELGFGFFEALTPESFANEI
ELLSSKPVAPKVVKPTTVANQAEVNADSSQAKRGIFKEKESVTDAKVSPAVSVPTSVSVNPAPHSNATSPNAALSSSAIP
KNTPSEVKAAAKKPAASAQDATLRVETSKIDTLVNLAGELVITQSMLTLIGNEMTGDLGERLKTALNELERNTREMQEAV
MSVRMLPVSFVFNRFNRLVRDLSEQLGKNVNLVIEGGNTEIDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRLAAGKSEVG
VLSLKASQRGGNIVIAVHDNGAGLNRERIIQKARESGLQVADNSSDKQIWQLIFAAGFSTAVEVTDVSGRGVGMDVVRRN
IEALGGRIDIESTEGQGSTFEIQLPLTLAIVDGMTVSVGNQIYILPLVHIIESIQPQTEQLKFLAKERLLKVREEYLPLL
NLYQLMEIEPNAKSPEEGIVVLLESNHKRFGLCVDALVGQQQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLAL
HIKN
>Mature_723_residues
SINMAEFHQVFFEESHEHLENMEQLLLALDLASPDPEELNTIFRAAHSIKGGSGIFGFTALTSVTHVMENLLDKTRKGNF
QLTSSIIDLLLSTVDTLSHILSLYREEEQIDWQEVEYSKSQLVAALNGESFSSSVAVRNGTDAANAPISPIIQAESVEKL
EDLGFGFFEDEMDRDIAIEGEDFGFFEVAYQAEEISAQSVVNYVSNTDKAADPFDFTSDDELGFGFFEALTPESFANEIE
LLSSKPVAPKVVKPTTVANQAEVNADSSQAKRGIFKEKESVTDAKVSPAVSVPTSVSVNPAPHSNATSPNAALSSSAIPK
NTPSEVKAAAKKPAASAQDATLRVETSKIDTLVNLAGELVITQSMLTLIGNEMTGDLGERLKTALNELERNTREMQEAVM
SVRMLPVSFVFNRFNRLVRDLSEQLGKNVNLVIEGGNTEIDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRLAAGKSEVGV
LSLKASQRGGNIVIAVHDNGAGLNRERIIQKARESGLQVADNSSDKQIWQLIFAAGFSTAVEVTDVSGRGVGMDVVRRNI
EALGGRIDIESTEGQGSTFEIQLPLTLAIVDGMTVSVGNQIYILPLVHIIESIQPQTEQLKFLAKERLLKVREEYLPLLN
LYQLMEIEPNAKSPEEGIVVLLESNHKRFGLCVDALVGQQQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLALH
IKN

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=411, Percent_Identity=53.7712895377129, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78892; Mature: 78761

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINMAEFHQVFFEESHEHLENMEQLLLALDLASPDPEELNTIFRAAHSIKGGSGIFGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
ALTSVTHVMENLLDKTRKGNFQLTSSIIDLLLSTVDTLSHILSLYREEEQIDWQEVEYSK
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SQLVAALNGESFSSSVAVRNGTDAANAPISPIIQAESVEKLEDLGFGFFEDEMDRDIAIE
HHEEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCEEEE
GEDFGFFEVAYQAEEISAQSVVNYVSNTDKAADPFDFTSDDELGFGFFEALTPESFANEI
CCCCCHHHEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHH
ELLSSKPVAPKVVKPTTVANQAEVNADSSQAKRGIFKEKESVTDAKVSPAVSVPTSVSVN
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHCCCCCCCCCEECCCCEECC
PAPHSNATSPNAALSSSAIPKNTPSEVKAAAKKPAASAQDATLRVETSKIDTLVNLAGEL
CCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
VITQSMLTLIGNEMTGDLGERLKTALNELERNTREMQEAVMSVRMLPVSFVFNRFNRLVR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLSEQLGKNVNLVIEGGNTEIDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRLAAGKSEVG
HHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCE
VLSLKASQRGGNIVIAVHDNGAGLNRERIIQKARESGLQVADNSSDKQIWQLIFAAGFST
EEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCC
AVEVTDVSGRGVGMDVVRRNIEALGGRIDIESTEGQGSTFEIQLPLTLAIVDGMTVSVGN
EEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECEEEEEECCEEEECCC
QIYILPLVHIIESIQPQTEQLKFLAKERLLKVREEYLPLLNLYQLMEIEPNAKSPEEGIV
EEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VLLESNHKRFGLCVDALVGQQQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLAL
EEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEEHHEE
HIKN
EECC
>Mature Secondary Structure 
SINMAEFHQVFFEESHEHLENMEQLLLALDLASPDPEELNTIFRAAHSIKGGSGIFGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
ALTSVTHVMENLLDKTRKGNFQLTSSIIDLLLSTVDTLSHILSLYREEEQIDWQEVEYSK
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SQLVAALNGESFSSSVAVRNGTDAANAPISPIIQAESVEKLEDLGFGFFEDEMDRDIAIE
HHEEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCEEEE
GEDFGFFEVAYQAEEISAQSVVNYVSNTDKAADPFDFTSDDELGFGFFEALTPESFANEI
CCCCCHHHEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHH
ELLSSKPVAPKVVKPTTVANQAEVNADSSQAKRGIFKEKESVTDAKVSPAVSVPTSVSVN
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHCCCCCCCCCEECCCCEECC
PAPHSNATSPNAALSSSAIPKNTPSEVKAAAKKPAASAQDATLRVETSKIDTLVNLAGEL
CCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
VITQSMLTLIGNEMTGDLGERLKTALNELERNTREMQEAVMSVRMLPVSFVFNRFNRLVR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLSEQLGKNVNLVIEGGNTEIDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRLAAGKSEVG
HHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCE
VLSLKASQRGGNIVIAVHDNGAGLNRERIIQKARESGLQVADNSSDKQIWQLIFAAGFST
EEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCC
AVEVTDVSGRGVGMDVVRRNIEALGGRIDIESTEGQGSTFEIQLPLTLAIVDGMTVSVGN
EEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECEEEEEECCEEEECCC
QIYILPLVHIIESIQPQTEQLKFLAKERLLKVREEYLPLLNLYQLMEIEPNAKSPEEGIV
EEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VLLESNHKRFGLCVDALVGQQQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLAL
EEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEEHHEE
HIKN
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]