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The map label for this gene is mmsB [H]

Identifier: 160874647

GI number: 160874647

Start: 1843052

End: 1843954

Strand: Direct

Name: mmsB [H]

Synonym: Sbal195_1530

Alternate gene names: 160874647

Gene position: 1843052-1843954 (Clockwise)

Preceding gene: 160874646

Following gene: 160874648

Centisome position: 34.47

GC content: 50.61

Gene sequence:

>903_bases
ATGAGTACAGTAGCATTTATCGGTTTAGGCAATATGGGCGGCCCAATGGCGGCCAATTTATTAAAAGCGGGCATGACGGT
TCGTGTATTTGATTTAGTCCCTGAAGCCATGCACAGCCTTGCCGAGCAAGGGGCTTTTGTTTCTAGCACGGCCTGCGGCG
CGGCGGCGGGTGCCAATGTGGTGATCACTATGCTGCCTGCGGGCAAGCATGTGAAAAGTTTATATTTAGGCAATGGCACA
GACAAAGGACTGCTCGAAGTGGTTGCGGGTGATACCTTACTGATCGATTGCTCGACTATCGATGCGCAAAGCGCGCAATT
GGTGGCGGCCGAAGCGGCTAAAAGCGGCATAGAGTTTATGGATGCACCGGTTTCTGGCGGCACAGCAGGCGCGGCGGCGG
GCACTTTAACCTTTATTTGTGGTGGTTCCGATAGCGCTTTTGAGCGTGGTCAGCCAGTGCTGAAAGCTATGGGGGTGAAC
ATATTCCATGCTGGTGGCCCAGGTGCGGGACAAGTCGCTAAAATCTGCAATAACATGCTGTTATCTGTGTTGATGGTCGG
CACTTCTGAGGCGTTGCAAATGGGCATTGACCATGGTCTCGATCCTAAAGTCTTGTCCGACATTATGAAGGTTAGCAGTG
GTGGTAACTGGACCCTCGAAAAGTATAATCCATGCCCAGGTGTGATGGAGACTGTACCTTCTTCTAAGGGCTATCAGGGC
GGCTTTATGGTAGATTTGATGGTTAAAGATCTCGGTCTGTCCCAAGAAGCCGCATTATTGAGCAACTCCAGCACGCCAAT
GGGCGCTTTAGCCCGCAGCTTGTATGTGAATCATGCAAGACAAGGCAACGGCCGCCGAGATTTTTCCAGTATTTTTGAAC
AATTTGCACAACTTAAAAAATAG

Upstream 100 bases:

>100_bases
GGCTCAGCCAAGCTCGCTTTATTCTGTGATAACGACAGCATAATCAATGGACTAGCAGTATCACTACACTAAAAAAAGAA
CAGCACACAGGAGTGACAGC

Downstream 100 bases:

>100_bases
ACATAGTTAACAAGGGATAACCAGATGGATTTAAAAGATAAGGTTGTCGTCATTACTGGCGGCGCGGGTGGCTTAGGTCT
AGCAATGGCGCAAAATTTTG

Product: 3-hydroxyisobutyrate dehydrogenase

Products: NA

Alternate protein names: HIBADH [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSTVAFIGLGNMGGPMAANLLKAGMTVRVFDLVPEAMHSLAEQGAFVSSTACGAAAGANVVITMLPAGKHVKSLYLGNGT
DKGLLEVVAGDTLLIDCSTIDAQSAQLVAAEAAKSGIEFMDAPVSGGTAGAAAGTLTFICGGSDSAFERGQPVLKAMGVN
IFHAGGPGAGQVAKICNNMLLSVLMVGTSEALQMGIDHGLDPKVLSDIMKVSSGGNWTLEKYNPCPGVMETVPSSKGYQG
GFMVDLMVKDLGLSQEAALLSNSSTPMGALARSLYVNHARQGNGRRDFSSIFEQFAQLKK

Sequences:

>Translated_300_residues
MSTVAFIGLGNMGGPMAANLLKAGMTVRVFDLVPEAMHSLAEQGAFVSSTACGAAAGANVVITMLPAGKHVKSLYLGNGT
DKGLLEVVAGDTLLIDCSTIDAQSAQLVAAEAAKSGIEFMDAPVSGGTAGAAAGTLTFICGGSDSAFERGQPVLKAMGVN
IFHAGGPGAGQVAKICNNMLLSVLMVGTSEALQMGIDHGLDPKVLSDIMKVSSGGNWTLEKYNPCPGVMETVPSSKGYQG
GFMVDLMVKDLGLSQEAALLSNSSTPMGALARSLYVNHARQGNGRRDFSSIFEQFAQLKK
>Mature_299_residues
STVAFIGLGNMGGPMAANLLKAGMTVRVFDLVPEAMHSLAEQGAFVSSTACGAAAGANVVITMLPAGKHVKSLYLGNGTD
KGLLEVVAGDTLLIDCSTIDAQSAQLVAAEAAKSGIEFMDAPVSGGTAGAAAGTLTFICGGSDSAFERGQPVLKAMGVNI
FHAGGPGAGQVAKICNNMLLSVLMVGTSEALQMGIDHGLDPKVLSDIMKVSSGGNWTLEKYNPCPGVMETVPSSKGYQGG
FMVDLMVKDLGLSQEAALLSNSSTPMGALARSLYVNHARQGNGRRDFSSIFEQFAQLKK

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI23308751, Length=292, Percent_Identity=45.8904109589041, Blast_Score=257, Evalue=9e-69,
Organism=Homo sapiens, GI40556376, Length=292, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1790315, Length=295, Percent_Identity=36.9491525423729, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI145693186, Length=299, Percent_Identity=33.1103678929766, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786719, Length=289, Percent_Identity=30.7958477508651, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789092, Length=295, Percent_Identity=30.5084745762712, Blast_Score=111, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17557316, Length=302, Percent_Identity=44.0397350993377, Blast_Score=232, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24655230, Length=297, Percent_Identity=40.7407407407407, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI19922568, Length=297, Percent_Identity=40.7407407407407, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI28574115, Length=300, Percent_Identity=24.3333333333333, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR015815
- InterPro:   IPR008927
- InterPro:   IPR006115
- InterPro:   IPR013328
- InterPro:   IPR011548
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03446 NAD_binding_2 [H]

EC number: =1.1.1.31 [H]

Molecular weight: Translated: 30738; Mature: 30607

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00895 3_HYDROXYISOBUT_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVAFIGLGNMGGPMAANLLKAGMTVRVFDLVPEAMHSLAEQGAFVSSTACGAAAGANV
CCEEEEEEECCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCE
VITMLPAGKHVKSLYLGNGTDKGLLEVVAGDTLLIDCSTIDAQSAQLVAAEAAKSGIEFM
EEEEECCCCCHHEEEECCCCCHHHHHEECCCEEEEEECCCCCCCHHHHHHHHHHCCCCEE
DAPVSGGTAGAAAGTLTFICGGSDSAFERGQPVLKAMGVNIFHAGGPGAGQVAKICNNML
ECCCCCCCCCCCCCEEEEEECCCCCHHHCCCHHHHHHCCEEEECCCCCHHHHHHHHHHHH
LSVLMVGTSEALQMGIDHGLDPKVLSDIMKVSSGGNWTLEKYNPCPGVMETVPSSKGYQG
HHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCCCCCCCC
GFMVDLMVKDLGLSQEAALLSNSSTPMGALARSLYVNHARQGNGRRDFSSIFEQFAQLKK
CEEEEEHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
STVAFIGLGNMGGPMAANLLKAGMTVRVFDLVPEAMHSLAEQGAFVSSTACGAAAGANV
CEEEEEEECCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCE
VITMLPAGKHVKSLYLGNGTDKGLLEVVAGDTLLIDCSTIDAQSAQLVAAEAAKSGIEFM
EEEEECCCCCHHEEEECCCCCHHHHHEECCCEEEEEECCCCCCCHHHHHHHHHHCCCCEE
DAPVSGGTAGAAAGTLTFICGGSDSAFERGQPVLKAMGVNIFHAGGPGAGQVAKICNNML
ECCCCCCCCCCCCCEEEEEECCCCCHHHCCCHHHHHHCCEEEECCCCCHHHHHHHHHHHH
LSVLMVGTSEALQMGIDHGLDPKVLSDIMKVSSGGNWTLEKYNPCPGVMETVPSSKGYQG
HHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCCCCCCCC
GFMVDLMVKDLGLSQEAALLSNSSTPMGALARSLYVNHARQGNGRRDFSSIFEQFAQLKK
CEEEEEHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339433; 10984043 [H]