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The map label for this gene is hmp [H]

Identifier: 160874236

GI number: 160874236

Start: 1314691

End: 1315884

Strand: Reverse

Name: hmp [H]

Synonym: Sbal195_1116

Alternate gene names: 160874236

Gene position: 1315884-1314691 (Counterclockwise)

Preceding gene: 160874237

Following gene: 160874234

Centisome position: 24.61

GC content: 48.16

Gene sequence:

>1194_bases
ATGTTGGACAGCCGTACAATCCAAGTTATCAAGAGCACTATTCCCTTACTCGAATCTGCAGGCCCTGCGCTGACGACCCA
TTTTTATCAACGCATGTTCAAACATAATCCTGAATTGAAAGATGTGTTCAATTTGGCGCACCAACATTCTGGTGGTCAGC
CTGTAGCCCTGTTCAATGCCGTCGCAGCCTATGCAAAAAATATCGAAAACTTAGCGGTACTGAGTTCAACGGTTGAGCGC
ATTGCCCAAAAACATACGGGATTTCTGATCAAACCTGAGCAGTATGCGATCGTCGGCAGCCATTTATTGGCAACGCTTAA
AGAATTAGGGGGCGATGCGGTAACAGAAGAAGTGTTAGAAGCTTGGGCACAGGCCTATGGATTTTTAGCCAACATCTTTA
TTCAGCGAGAAGCACAGATTTATCAAGCGCATGCAGAGCAAGATGGTGGCTGGTTGGGTGAGCGTCAGTTTATCATTAGC
GCGAAAAATACCGAGTCAGCAGTCATCACCTCCTTCATATTAACGCCTGAAGATGGCAAGCCAGTTAAAGATTTTATCCC
TGGTCAGTATTTAAGTTTGAAGCTAACACACCCGAATTTGGCATATGAAGAAATCCGCCAATATTCCTTATCCGATGCAC
CAAATGGCACCAGCTACCGCATCAGTGTAAAACGCGAACTCGGCGGACAAGTGTCGAACCTGCTGCATGATGCGATACAC
GTCGGCGACAAAATCGCAGTGATGCCACCCGCAGGGGACTTTACCCTAGAAGTCACGGCGGACACGCCCGTAGTACTTAT
TTCAGCAGGTGTAGGCCAAACACCGATGAAAAGTATGCTCAATCAATTACTCAAGCTGCAGCATCCCAGCACTATCACTT
GGCTGCATGCCTGTGAGCAAGGCGCCGTACACGGGTTCAAACAGGCTATCCACGCCAAGCGCCAGCAACATCATAATCTG
ACGAGTCATGTTTGGTATCGTGAGCCAGCCCCAACCGATAAGTTGGGTGATGATTATGATTTCGAAGGACAAATGGAGTT
AAGTAAAGTCGCCGAACAGTTGCTTCCCCACGCACGTTATTATTTCTGCGGCCCCATTGGATTCATGTCAGCCATCAAGC
AACAACTACTCGCTCTGGGTGTCGCGGCTGAAAGCATGCACTATGAAGTGTTCGGCCCTCACGCCGATCTTTAA

Upstream 100 bases:

>100_bases
GTTATCGATAGCACGGATAGCGATAATCTCTATTGATCCAAATCAAATAGATCTTTAAACTCATTAAACATTCATAATAT
TTACACGTTAAGGATTTTCT

Downstream 100 bases:

>100_bases
TGGCATGACACGGACTTGAGAAAATGCACGCTCAGGTCCGTTTGAATGCTTAGCTTTTATGCTTAGCTTTTATGCTTAGC
TTTCATTGTTAGCATGGCAA

Product: globin

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLDSRTIQVIKSTIPLLESAGPALTTHFYQRMFKHNPELKDVFNLAHQHSGGQPVALFNAVAAYAKNIENLAVLSSTVER
IAQKHTGFLIKPEQYAIVGSHLLATLKELGGDAVTEEVLEAWAQAYGFLANIFIQREAQIYQAHAEQDGGWLGERQFIIS
AKNTESAVITSFILTPEDGKPVKDFIPGQYLSLKLTHPNLAYEEIRQYSLSDAPNGTSYRISVKRELGGQVSNLLHDAIH
VGDKIAVMPPAGDFTLEVTADTPVVLISAGVGQTPMKSMLNQLLKLQHPSTITWLHACEQGAVHGFKQAIHAKRQQHHNL
TSHVWYREPAPTDKLGDDYDFEGQMELSKVAEQLLPHARYYFCGPIGFMSAIKQQLLALGVAAESMHYEVFGPHADL

Sequences:

>Translated_397_residues
MLDSRTIQVIKSTIPLLESAGPALTTHFYQRMFKHNPELKDVFNLAHQHSGGQPVALFNAVAAYAKNIENLAVLSSTVER
IAQKHTGFLIKPEQYAIVGSHLLATLKELGGDAVTEEVLEAWAQAYGFLANIFIQREAQIYQAHAEQDGGWLGERQFIIS
AKNTESAVITSFILTPEDGKPVKDFIPGQYLSLKLTHPNLAYEEIRQYSLSDAPNGTSYRISVKRELGGQVSNLLHDAIH
VGDKIAVMPPAGDFTLEVTADTPVVLISAGVGQTPMKSMLNQLLKLQHPSTITWLHACEQGAVHGFKQAIHAKRQQHHNL
TSHVWYREPAPTDKLGDDYDFEGQMELSKVAEQLLPHARYYFCGPIGFMSAIKQQLLALGVAAESMHYEVFGPHADL
>Mature_397_residues
MLDSRTIQVIKSTIPLLESAGPALTTHFYQRMFKHNPELKDVFNLAHQHSGGQPVALFNAVAAYAKNIENLAVLSSTVER
IAQKHTGFLIKPEQYAIVGSHLLATLKELGGDAVTEEVLEAWAQAYGFLANIFIQREAQIYQAHAEQDGGWLGERQFIIS
AKNTESAVITSFILTPEDGKPVKDFIPGQYLSLKLTHPNLAYEEIRQYSLSDAPNGTSYRISVKRELGGQVSNLLHDAIH
VGDKIAVMPPAGDFTLEVTADTPVVLISAGVGQTPMKSMLNQLLKLQHPSTITWLHACEQGAVHGFKQAIHAKRQQHHNL
TSHVWYREPAPTDKLGDDYDFEGQMELSKVAEQLLPHARYYFCGPIGFMSAIKQQLLALGVAAESMHYEVFGPHADL

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=395, Percent_Identity=54.1772151898734, Blast_Score=436, Evalue=1e-124,
Organism=Escherichia coli, GI1788104, Length=232, Percent_Identity=27.1551724137931, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787658, Length=234, Percent_Identity=26.9230769230769, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321673, Length=410, Percent_Identity=35.1219512195122, Blast_Score=220, Evalue=3e-58,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43881; Mature: 43881

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSRTIQVIKSTIPLLESAGPALTTHFYQRMFKHNPELKDVFNLAHQHSGGQPVALFNA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHH
VAAYAKNIENLAVLSSTVERIAQKHTGFLIKPEQYAIVGSHLLATLKELGGDAVTEEVLE
HHHHHHCHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AWAQAYGFLANIFIQREAQIYQAHAEQDGGWLGERQFIISAKNTESAVITSFILTPEDGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCC
PVKDFIPGQYLSLKLTHPNLAYEEIRQYSLSDAPNGTSYRISVKRELGGQVSNLLHDAIH
CHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHCHHHHHHHHHHHH
VGDKIAVMPPAGDFTLEVTADTPVVLISAGVGQTPMKSMLNQLLKLQHPSTITWLHACEQ
CCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
GAVHGFKQAIHAKRQQHHNLTSHVWYREPAPTDKLGDDYDFEGQMELSKVAEQLLPHARY
HHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
YFCGPIGFMSAIKQQLLALGVAAESMHYEVFGPHADL
EEECHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCC
>Mature Secondary Structure
MLDSRTIQVIKSTIPLLESAGPALTTHFYQRMFKHNPELKDVFNLAHQHSGGQPVALFNA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHH
VAAYAKNIENLAVLSSTVERIAQKHTGFLIKPEQYAIVGSHLLATLKELGGDAVTEEVLE
HHHHHHCHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AWAQAYGFLANIFIQREAQIYQAHAEQDGGWLGERQFIISAKNTESAVITSFILTPEDGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCC
PVKDFIPGQYLSLKLTHPNLAYEEIRQYSLSDAPNGTSYRISVKRELGGQVSNLLHDAIH
CHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHCHHHHHHHHHHHH
VGDKIAVMPPAGDFTLEVTADTPVVLISAGVGQTPMKSMLNQLLKLQHPSTITWLHACEQ
CCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
GAVHGFKQAIHAKRQQHHNLTSHVWYREPAPTDKLGDDYDFEGQMELSKVAEQLLPHARY
HHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
YFCGPIGFMSAIKQQLLALGVAAESMHYEVFGPHADL
EEECHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]