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The map label for this gene is hlyB [H]

Identifier: 160874237

GI number: 160874237

Start: 1316144

End: 1317769

Strand: Reverse

Name: hlyB [H]

Synonym: Sbal195_1117

Alternate gene names: 160874237

Gene position: 1317769-1316144 (Counterclockwise)

Preceding gene: 160874238

Following gene: 160874236

Centisome position: 24.64

GC content: 46.92

Gene sequence:

>1626_bases
ATGAACGGTCTACAAATAAAACAAAAAATGTTTATCGGTATTTTGGTCCCCCTTGCAATGTTACTGACGATTGGTTTTCT
CGCCATTAATATGATGGGCAACATTGAGTCGGGTGTTGAACGCATCTATAACGACAGAGTGGTGCCGCTGGATGATTTAA
AAGTGATTGCCGATAAGTATGCGGTCGATGTTATCGATGCGGTAAATAAGGCGAACGCGGGTGGTTTCACCGCCTCGCAA
GCGGCTGAAGCGCTAGACAGTGCCAAATCGACTATTACTCAACATTGGCAAAAATACCTATCTACCGAGCTTACCTCAGA
AGAATCCCGACTAGTAAAACAAGCCGAAGTGCTGTTCTCCCCCGCGAATCAACAGATTGATACCCTGATTTCGCGCTTAA
GAGGATTAAACGGTGATGTTTCAAACCAACTCTCAGCCAATATCCTGCCGCTGTACCAAGCAATTGATCCTATCAGTAAC
CAAATATCTGAACTGATTGCACTGCAAATCCGCGTGGCGGGCGAAGAAAAAGATCGTGTAAATGCCATTTATCAATCTTC
AATCACTATTTTTATGGCATTAGCCTGTGCCGCCATGATCATCAGTATTGTGATTGGACTCTGGGTCAATCGCAGCGTGA
TGAATCCCATTAATGACATCCTTGGTAAACTGAAAAGGATCCATCAAGACTCAGATCTCACCGTCAGATTCACCACTTTT
AATCACGATGAGTTAGGCCAAATATCCACGAGCCTCACCCAAGTGATTGAACACTTACGGGGCATTCTTCATTCCATTGC
CAAGGCAGCAACTACGGTCAACAGTTCGGCAAATGAGTTAGGTAGCTTCACCCAAGCCACCAATAAACGGATGCAACAGC
AACAAGCCGAAACGGAGCAGACTGCAACGGCCATGAATGAGATGACGGCCACCGTTGCCGAAGTCGCCCAAAGCGCATCT
GCCGCGGCAGATTCAGCCAAAGATGCCGATACCTATGCCGCCAACGGCAATAATATTGTGATGCAATCGATTAGCAGTAT
GTCGCAGCTTTCTGATCAAATTCAAAAAACGGCGCAGGTCATTGGATTCTTATCTAATGAAAGCCAAAACATCGGCCGCG
TACTCGATGTGATTAAGAGTATTGCCGAACAAACCAATTTACTGGCACTCAATGCCGCCATCGAAGCCGCACGGGCTGGA
GAGCAAGGTCGCGGCTTTGCAGTCGTGGCCGATGAAGTGCGAACCTTAGCGCAACGCACCCAAAAATCGACTCAAGAAAT
TGAGGCCATGATTGCTACCCTACAACAAGGGGTTAAAGAAGCCGTCAGCGCCATGGAAATCGGAATCAATCAAGTAGATG
ATGCCAATGATAAAGCCAATCAGGCGGGTCAAGCGCTGAAAGAAATTGTCACCTCAGTAGACAGCATCACCGAGCTAAAT
ACCCACATTGCGACCGCAGCTGAAGAGCAAAGTAGCGTTGCCGAGAGTATTAATCGCAGCATTATTGCCATCAGCGATAT
CGCCGAGCATTCCACAGCTTCGGCGACTGAATTAAGTGAATCTGTGATTAATTTGACTAAGCTCGCCAGCAGCATGCGCA
ATCAAGTGAGCGCATTTAAGCTCTAA

Upstream 100 bases:

>100_bases
CCTCTTTCCGCTGATTTGCTATACCTAATGTTACAGACTCATTATAGGGATAGCTCGAGCTCTGCCTAAAGGACTCTTTA
GTTCACTGAGGCTATCCCAT

Downstream 100 bases:

>100_bases
TTTAACTCAATCAACCACCAAACGACTGCAACCATTTTTGCTGTTGCAGTCAAACTCCTTTATTCACATCATCTGTAACC
CATTGAAATAAAATATCCGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNGLQIKQKMFIGILVPLAMLLTIGFLAINMMGNIESGVERIYNDRVVPLDDLKVIADKYAVDVIDAVNKANAGGFTASQ
AAEALDSAKSTITQHWQKYLSTELTSEESRLVKQAEVLFSPANQQIDTLISRLRGLNGDVSNQLSANILPLYQAIDPISN
QISELIALQIRVAGEEKDRVNAIYQSSITIFMALACAAMIISIVIGLWVNRSVMNPINDILGKLKRIHQDSDLTVRFTTF
NHDELGQISTSLTQVIEHLRGILHSIAKAATTVNSSANELGSFTQATNKRMQQQQAETEQTATAMNEMTATVAEVAQSAS
AAADSAKDADTYAANGNNIVMQSISSMSQLSDQIQKTAQVIGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTQKSTQEIEAMIATLQQGVKEAVSAMEIGINQVDDANDKANQAGQALKEIVTSVDSITELN
THIATAAEEQSSVAESINRSIIAISDIAEHSTASATELSESVINLTKLASSMRNQVSAFKL

Sequences:

>Translated_541_residues
MNGLQIKQKMFIGILVPLAMLLTIGFLAINMMGNIESGVERIYNDRVVPLDDLKVIADKYAVDVIDAVNKANAGGFTASQ
AAEALDSAKSTITQHWQKYLSTELTSEESRLVKQAEVLFSPANQQIDTLISRLRGLNGDVSNQLSANILPLYQAIDPISN
QISELIALQIRVAGEEKDRVNAIYQSSITIFMALACAAMIISIVIGLWVNRSVMNPINDILGKLKRIHQDSDLTVRFTTF
NHDELGQISTSLTQVIEHLRGILHSIAKAATTVNSSANELGSFTQATNKRMQQQQAETEQTATAMNEMTATVAEVAQSAS
AAADSAKDADTYAANGNNIVMQSISSMSQLSDQIQKTAQVIGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTQKSTQEIEAMIATLQQGVKEAVSAMEIGINQVDDANDKANQAGQALKEIVTSVDSITELN
THIATAAEEQSSVAESINRSIIAISDIAEHSTASATELSESVINLTKLASSMRNQVSAFKL
>Mature_541_residues
MNGLQIKQKMFIGILVPLAMLLTIGFLAINMMGNIESGVERIYNDRVVPLDDLKVIADKYAVDVIDAVNKANAGGFTASQ
AAEALDSAKSTITQHWQKYLSTELTSEESRLVKQAEVLFSPANQQIDTLISRLRGLNGDVSNQLSANILPLYQAIDPISN
QISELIALQIRVAGEEKDRVNAIYQSSITIFMALACAAMIISIVIGLWVNRSVMNPINDILGKLKRIHQDSDLTVRFTTF
NHDELGQISTSLTQVIEHLRGILHSIAKAATTVNSSANELGSFTQATNKRMQQQQAETEQTATAMNEMTATVAEVAQSAS
AAADSAKDADTYAANGNNIVMQSISSMSQLSDQIQKTAQVIGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTQKSTQEIEAMIATLQQGVKEAVSAMEIGINQVDDANDKANQAGQALKEIVTSVDSITELN
THIATAAEEQSSVAESINRSIIAISDIAEHSTASATELSESVINLTKLASSMRNQVSAFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=476, Percent_Identity=28.9915966386555, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI2367378, Length=327, Percent_Identity=32.1100917431193, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1788194, Length=363, Percent_Identity=31.129476584022, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=30.794701986755, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1789453, Length=259, Percent_Identity=30.8880308880309, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58192; Mature: 58192

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLQIKQKMFIGILVPLAMLLTIGFLAINMMGNIESGVERIYNDRVVPLDDLKVIADKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
AVDVIDAVNKANAGGFTASQAAEALDSAKSTITQHWQKYLSTELTSEESRLVKQAEVLFS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
PANQQIDTLISRLRGLNGDVSNQLSANILPLYQAIDPISNQISELIALQIRVAGEEKDRV
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
NAIYQSSITIFMALACAAMIISIVIGLWVNRSVMNPINDILGKLKRIHQDSDLTVRFTTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
NHDELGQISTSLTQVIEHLRGILHSIAKAATTVNSSANELGSFTQATNKRMQQQQAETEQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
TATAMNEMTATVAEVAQSASAAADSAKDADTYAANGNNIVMQSISSMSQLSDQIQKTAQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
QKSTQEIEAMIATLQQGVKEAVSAMEIGINQVDDANDKANQAGQALKEIVTSVDSITELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
THIATAAEEQSSVAESINRSIIAISDIAEHSTASATELSESVINLTKLASSMRNQVSAFK
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure
MNGLQIKQKMFIGILVPLAMLLTIGFLAINMMGNIESGVERIYNDRVVPLDDLKVIADKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
AVDVIDAVNKANAGGFTASQAAEALDSAKSTITQHWQKYLSTELTSEESRLVKQAEVLFS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
PANQQIDTLISRLRGLNGDVSNQLSANILPLYQAIDPISNQISELIALQIRVAGEEKDRV
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
NAIYQSSITIFMALACAAMIISIVIGLWVNRSVMNPINDILGKLKRIHQDSDLTVRFTTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
NHDELGQISTSLTQVIEHLRGILHSIAKAATTVNSSANELGSFTQATNKRMQQQQAETEQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
TATAMNEMTATVAEVAQSASAAADSAKDADTYAANGNNIVMQSISSMSQLSDQIQKTAQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
QKSTQEIEAMIATLQQGVKEAVSAMEIGINQVDDANDKANQAGQALKEIVTSVDSITELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
THIATAAEEQSSVAESINRSIIAISDIAEHSTASATELSESVINLTKLASSMRNQVSAFK
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]