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The map label for this gene is thrC [H]

Identifier: 159901020

GI number: 159901020

Start: 5770837

End: 5771910

Strand: Direct

Name: thrC [H]

Synonym: Haur_4507

Alternate gene names: 159901020

Gene position: 5770837-5771910 (Clockwise)

Preceding gene: 159901019

Following gene: 159901021

Centisome position: 90.93

GC content: 53.72

Gene sequence:

>1074_bases
ATGAGTCAGCTAACCACCCATGCTTCGGCGGTGCCATTACTCGAACGCTACCGCCAATTTTTGCCGATCACTGCCCAAAC
GCCAATTGTCACCTTGCACGAGGGCAATACACCGTTGATCAATGTGCCACGCTTGGCTGCCCACCTTGGGGTGCGCGAAT
TGTGGCTCAAATTGGAATCCATGAATCCAACTGGTTCGTTCAAGGATCGCGGCATGGTCATGGCGATTGCCAAAGCACTC
GAAGCTGGCAGCAAAGCCGTGGTCTGCGCCTCAACTGGCAATACCAGTGCTGCCGCCGCTGCCTATGCCGCTCGGATGGG
CATGGAATGTGTAGTGGTCGTGCCTGCTGGCAAAATCGCCTTAGGTAAATTGGCTCAAGCTTTGATGTACGGAGCCAAAC
TCTTGGTGATCGAAGGCAATTTCGACCAAGCCTTGGATATGGTGCGCGTGTTGGCCGAACAACACCCAATTACTTTGGTC
AACTCGGTTAACCCCTATCGTTTGGAAGGCCAAGCGACCGCTGCCTACGAAATTTGCGATGTGCTCGGCGATGCACCCGA
TTATTTGGCCTTGCCAGTTGGGAATGCTGGCAATATTTCGGCCTATTGGATGGGCTTCAAACGCTATTATGAAGCGCATC
GCTCGGAAAGCTTGCCCAAAATTTTGGGTTTTGAGGCAACTGGTTCGGCAGCAATCGTGCGCGGTGAGCCAATTGCTTAT
CCTGAAACCGTGGCAACCGCGATTCGAATTGGCAATCCGGCTTCGTGGCAGTTGGCAGTTAATGCTCGCGACGAATCGGA
AGGCACGATCGATCATGTTAGCGATGAAGAAATTTTGGCGGCATGGCGCGATCTCTCGGCACTCGAAGGTATTTTCTGCG
AACCAGCTTCGGCAGCAGGGGTTGCCGGCATTCGCAAGCTTTTGGCTGCTGGCAGCATCGATCCCAATGGCCGGTTTGTG
GCAGTTTTGACTGGCCATGGCTTGAAAGATCCACAATTGGCTGTTGAGCAGTTCTCGGTTCCACAGGCGATCCCTGCTGA
ATTGAGCGCTGTGGTCGCCGCCTTAGATTTGTAG

Upstream 100 bases:

>100_bases
AACTAACTCAACAATAATCTAAATATGTTATAATCAGCGCCATCGGCGATGATGCCCTTTTCCGCATTGGGAAGGGGCTT
TTTTGTAGGACACACCAGCT

Downstream 100 bases:

>100_bases
TGGCGCGGTGAGAGTGAGCAAGGTTTTGACGCTATTGATTTAGCCACATTCAGGCTTTTGAGCAGCAACTTAATTGCTGG
GGGCAAAAGGTTGTTGAGTT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSQLTTHASAVPLLERYRQFLPITAQTPIVTLHEGNTPLINVPRLAAHLGVRELWLKLESMNPTGSFKDRGMVMAIAKAL
EAGSKAVVCASTGNTSAAAAAYAARMGMECVVVVPAGKIALGKLAQALMYGAKLLVIEGNFDQALDMVRVLAEQHPITLV
NSVNPYRLEGQATAAYEICDVLGDAPDYLALPVGNAGNISAYWMGFKRYYEAHRSESLPKILGFEATGSAAIVRGEPIAY
PETVATAIRIGNPASWQLAVNARDESEGTIDHVSDEEILAAWRDLSALEGIFCEPASAAGVAGIRKLLAAGSIDPNGRFV
AVLTGHGLKDPQLAVEQFSVPQAIPAELSAVVAALDL

Sequences:

>Translated_357_residues
MSQLTTHASAVPLLERYRQFLPITAQTPIVTLHEGNTPLINVPRLAAHLGVRELWLKLESMNPTGSFKDRGMVMAIAKAL
EAGSKAVVCASTGNTSAAAAAYAARMGMECVVVVPAGKIALGKLAQALMYGAKLLVIEGNFDQALDMVRVLAEQHPITLV
NSVNPYRLEGQATAAYEICDVLGDAPDYLALPVGNAGNISAYWMGFKRYYEAHRSESLPKILGFEATGSAAIVRGEPIAY
PETVATAIRIGNPASWQLAVNARDESEGTIDHVSDEEILAAWRDLSALEGIFCEPASAAGVAGIRKLLAAGSIDPNGRFV
AVLTGHGLKDPQLAVEQFSVPQAIPAELSAVVAALDL
>Mature_356_residues
SQLTTHASAVPLLERYRQFLPITAQTPIVTLHEGNTPLINVPRLAAHLGVRELWLKLESMNPTGSFKDRGMVMAIAKALE
AGSKAVVCASTGNTSAAAAAYAARMGMECVVVVPAGKIALGKLAQALMYGAKLLVIEGNFDQALDMVRVLAEQHPITLVN
SVNPYRLEGQATAAYEICDVLGDAPDYLALPVGNAGNISAYWMGFKRYYEAHRSESLPKILGFEATGSAAIVRGEPIAYP
ETVATAIRIGNPASWQLAVNARDESEGTIDHVSDEEILAAWRDLSALEGIFCEPASAAGVAGIRKLLAAGSIDPNGRFVA
VLTGHGLKDPQLAVEQFSVPQAIPAELSAVVAALDL

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=321, Percent_Identity=28.6604361370716, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790207, Length=313, Percent_Identity=28.7539936102236, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37739; Mature: 37608

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLTTHASAVPLLERYRQFLPITAQTPIVTLHEGNTPLINVPRLAAHLGVRELWLKLES
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEECCHHHHHHCHHHHHHHHCC
MNPTGSFKDRGMVMAIAKALEAGSKAVVCASTGNTSAAAAAYAARMGMECVVVVPAGKIA
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHH
LGKLAQALMYGAKLLVIEGNFDQALDMVRVLAEQHPITLVNSVNPYRLEGQATAAYEICD
HHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCHHHHHHHH
VLGDAPDYLALPVGNAGNISAYWMGFKRYYEAHRSESLPKILGFEATGSAAIVRGEPIAY
HHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCC
PETVATAIRIGNPASWQLAVNARDESEGTIDHVSDEEILAAWRDLSALEGIFCEPASAAG
HHHHHHHEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCH
VAGIRKLLAAGSIDPNGRFVAVLTGHGLKDPQLAVEQFSVPQAIPAELSAVVAALDL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SQLTTHASAVPLLERYRQFLPITAQTPIVTLHEGNTPLINVPRLAAHLGVRELWLKLES
CCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEECCHHHHHHCHHHHHHHHCC
MNPTGSFKDRGMVMAIAKALEAGSKAVVCASTGNTSAAAAAYAARMGMECVVVVPAGKIA
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHH
LGKLAQALMYGAKLLVIEGNFDQALDMVRVLAEQHPITLVNSVNPYRLEGQATAAYEICD
HHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCHHHHHHHH
VLGDAPDYLALPVGNAGNISAYWMGFKRYYEAHRSESLPKILGFEATGSAAIVRGEPIAY
HHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCC
PETVATAIRIGNPASWQLAVNARDESEGTIDHVSDEEILAAWRDLSALEGIFCEPASAAG
HHHHHHHEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCH
VAGIRKLLAAGSIDPNGRFVAVLTGHGLKDPQLAVEQFSVPQAIPAELSAVVAALDL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3098560; 9384377; 3139660 [H]