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The map label for this gene is accD

Identifier: 159900054

GI number: 159900054

Start: 4451444

End: 4452340

Strand: Direct

Name: accD

Synonym: Haur_3537

Alternate gene names: 159900054

Gene position: 4451444-4452340 (Clockwise)

Preceding gene: 159900053

Following gene: 159900055

Centisome position: 70.14

GC content: 50.84

Gene sequence:

>897_bases
TTGAAAGATTTTTTTCGGCGTGCGCCGTTACCCTTCACGTCTTCGCGGCGTGAGCAACAAATACCAGATAATGTTTGGGC
CAAATGCGCCAATTGTGGCGAATTGACCTATCAAAAACAATTCAATGATGCCTTAAAAGTCTGTCCAAAATGCAGCTATC
ACTCGCGGATTAGCTCACGCGAATGGATTGAAGTTTTGGCTGATGCTGATTCATTCGTCGAATATGATGCTGATCTACAA
GGGATCGACATTTTGGGCTTTGTTAGCCCCAAAGATAATTACGAAGCGAAATTAGCTGCCACCAGCGAACGCACTGGCAC
TAACGATGTTGTGATGAGCGGTAGCGCCAGCATCGAAGGCTTGCCATTTGAAATCGCAGCCTGTAATTTTGAATTTATGG
GCGGTTCGATGGGCAGCGTCTTTGGCGAAAAAGTGGCACGAGCAGTCGAACGAGCAGCCGATCGTGGCGTACCAGTGCTG
ACGATCAACGCTTCGGGTGGCGCTCGTATGCACGAAGGCATTTTTGCCCTGATGCAAATGGCCAAAGTTTCGGTTGCGCT
CACCCGTTTGGCTCGGGTGCGCCAGCCCCATATCTCGCTCTTAGTTGACCCTTGCTATGGCGGGGTTTCAGCCTCGTATG
CCTCGGTTGCCGATATTATTTTGGCCGAACCAGGTGCGAATATTGGCTTTGCTGGGCGACGGGTGATTGAGCAAACGATT
CGCCAAAAATTGCCACCAAACTTCCAAACCGCAGAATTTTTCCTTGAACATGGCATGATCGATGCAGTTGTGCCACGCTC
GGACATGCGGGCAACCATCGGGCGTTTGTTGCGCCTGTATCAACGCCCCACATCATCGGCTGATCATCGCGAACATGTCG
TAGCGGGCCACCAATAA

Upstream 100 bases:

>100_bases
ATGGGAGAAACTGAAATGGTTCAAAAACAGCCGTCCATGACGCACTGCGTGCTATGCTATAATCCCAATACGGCTCAAAA
ATGACCGTGGAGGTTCCGAT

Downstream 100 bases:

>100_bases
GCCCCACGCAGAGGTCAAAACGTGACAACGTTAACTGAGTTATTGCCTTGGGATAAGGTGCAAATCGCCCGTAATCCCCA
ACGCCCACGCACCCTTGATT

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKDFFRRAPLPFTSSRREQQIPDNVWAKCANCGELTYQKQFNDALKVCPKCSYHSRISSREWIEVLADADSFVEYDADLQ
GIDILGFVSPKDNYEAKLAATSERTGTNDVVMSGSASIEGLPFEIAACNFEFMGGSMGSVFGEKVARAVERAADRGVPVL
TINASGGARMHEGIFALMQMAKVSVALTRLARVRQPHISLLVDPCYGGVSASYASVADIILAEPGANIGFAGRRVIEQTI
RQKLPPNFQTAEFFLEHGMIDAVVPRSDMRATIGRLLRLYQRPTSSADHREHVVAGHQ

Sequences:

>Translated_298_residues
MKDFFRRAPLPFTSSRREQQIPDNVWAKCANCGELTYQKQFNDALKVCPKCSYHSRISSREWIEVLADADSFVEYDADLQ
GIDILGFVSPKDNYEAKLAATSERTGTNDVVMSGSASIEGLPFEIAACNFEFMGGSMGSVFGEKVARAVERAADRGVPVL
TINASGGARMHEGIFALMQMAKVSVALTRLARVRQPHISLLVDPCYGGVSASYASVADIILAEPGANIGFAGRRVIEQTI
RQKLPPNFQTAEFFLEHGMIDAVVPRSDMRATIGRLLRLYQRPTSSADHREHVVAGHQ
>Mature_298_residues
MKDFFRRAPLPFTSSRREQQIPDNVWAKCANCGELTYQKQFNDALKVCPKCSYHSRISSREWIEVLADADSFVEYDADLQ
GIDILGFVSPKDNYEAKLAATSERTGTNDVVMSGSASIEGLPFEIAACNFEFMGGSMGSVFGEKVARAVERAADRGVPVL
TINASGGARMHEGIFALMQMAKVSVALTRLARVRQPHISLLVDPCYGGVSASYASVADIILAEPGANIGFAGRRVIEQTI
RQKLPPNFQTAEFFLEHGMIDAVVPRSDMRATIGRLLRLYQRPTSSADHREHVVAGHQ

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Homo sapiens, GI119943100, Length=160, Percent_Identity=29.375, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI295821216, Length=168, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788655, Length=280, Percent_Identity=45, Blast_Score=250, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI25147362, Length=161, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25147359, Length=161, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_HERA2 (A9B536)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546301.1
- ProteinModelPortal:   A9B536
- SMR:   A9B536
- GeneID:   5735396
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3537
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   CLSK972927
- BioCyc:   HAUR316274:HAUR_3537-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32718; Mature: 32718

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFFRRAPLPFTSSRREQQIPDNVWAKCANCGELTYQKQFNDALKVCPKCSYHSRISSR
CCCHHHHCCCCCCCCCHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHCCHH
EWIEVLADADSFVEYDADLQGIDILGFVSPKDNYEAKLAATSERTGTNDVVMSGSASIEG
HHHHHHHCCHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCEEEECCCCCCC
LPFEIAACNFEFMGGSMGSVFGEKVARAVERAADRGVPVLTINASGGARMHEGIFALMQM
CCEEEEEECEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
AKVSVALTRLARVRQPHISLLVDPCYGGVSASYASVADIILAEPGANIGFAGRRVIEQTI
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHH
RQKLPPNFQTAEFFLEHGMIDAVVPRSDMRATIGRLLRLYQRPTSSADHREHVVAGHQ
HHHCCCCCHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MKDFFRRAPLPFTSSRREQQIPDNVWAKCANCGELTYQKQFNDALKVCPKCSYHSRISSR
CCCHHHHCCCCCCCCCHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHCCHH
EWIEVLADADSFVEYDADLQGIDILGFVSPKDNYEAKLAATSERTGTNDVVMSGSASIEG
HHHHHHHCCHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCEEEECCCCCCC
LPFEIAACNFEFMGGSMGSVFGEKVARAVERAADRGVPVLTINASGGARMHEGIFALMQM
CCEEEEEECEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
AKVSVALTRLARVRQPHISLLVDPCYGGVSASYASVADIILAEPGANIGFAGRRVIEQTI
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHH
RQKLPPNFQTAEFFLEHGMIDAVVPRSDMRATIGRLLRLYQRPTSSADHREHVVAGHQ
HHHCCCCCHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA