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The map label for this gene is yngJ [H]

Identifier: 159899987

GI number: 159899987

Start: 4371986

End: 4373173

Strand: Direct

Name: yngJ [H]

Synonym: Haur_3470

Alternate gene names: 159899987

Gene position: 4371986-4373173 (Clockwise)

Preceding gene: 159899986

Following gene: 159899988

Centisome position: 68.89

GC content: 50.67

Gene sequence:

>1188_bases
ATGACGATGCAAGAGCACACCGCCGACCCCGCCTTGGACTTCTACCAATTTGATTTGCTGTTAACGCCTGAAGAGCGTGA
AGTACGTGATCGGGTGCGTGGCTTTATGCAGCGTGAAGTTAAGCCGATCATCAACGAATATTGGGAGAAGGGCGAATTTC
CGTTCGAGTTAATTCCTAAGTTGGCTGAACTCAAGGTCTGTGGCGGCACGATTCAGGGCTATGGCTGCCCAGGCTTATCG
AGCGTGGCAACTGGCTTGGTTGCTGCCGAAATGGCCAAAATTGATGGCTCAGTTTGTACCTTTTTTGGCGTAACCAGCGG
CTTGGCGATGTCGAGCATCTATTATTGTGGCTCAGAAGCCCAAAAAGAATATTGGTTGCCCAAATTGGCTTCGATGGAAA
AAATTGGGGCATTTGCCCTGACTGAGCCAGATAACGGCTCAGATGCCTCGCATATTCAAACCACTGCCCGCCTAGAGGGC
GACCACTATGTGCTCAACGGCCAAAAACGCTGGATTGGCAACGCCTCGTTTGCCGATGTAATTATTGTTTGGGCACGCGA
TGAAGCCACCAATCAAGTGACAGGCTTCTTGGTCGAAAAAGGGACTCCAGGCTTTGAAGCAACCGTGATGCATGGCAAAA
TTGCCAAACGCGCCCTGTGGAATGCCGAAATCAAGCTCGAAAATTGTCGCATTCCCGCCAGCAATCGTCTCGAAAAAGCA
CGATCGTTCAAAGATACAGCGGTTGTGTTGGCCAACACCCGTTTTGGCGTAGCATGGGAAGGCGTGGGGCATGCCCAAGC
TGCCTATGAAATGGCCTTGCGCTATAGCCAAGAACGCAAACAGTTTGGCAAGCCAATCGCTGGCTACCAATTAATTCAAG
AAAAATTGGTTAAAATGCTGGCAGAAGTGGTGGCGATGGAATTAACCACTTGGCGTTTGAGCGTATTGCGCGACCAAGGC
TTGATGACCGATGGTCAATCGTCGCTGGCCAAGATGAACAATTCAGCCAAAGCTCGCCAAATTGTGGCCCTAGGCCGCGA
AATCTTTGGTGGCAACGGCTTGTTGCTCGAAAATCATATCGCCCGCCATTTTGCTGATATGGAAGCGGTGTATACCTACG
AAGGCAGCAACGAAATCAATACGCTCGTCGTTGGTCGCGAAATTACCGGCGTACCAGCCTTCGTCTAA

Upstream 100 bases:

>100_bases
TTTTGACTTCTGCCTTTTGATTTTCAAAAAGTGTGGTATAGTGAATAACGCAGTGCGTCATCCTCGATCCGACGCAAGAT
CATATAAGGAGAATCCATCA

Downstream 100 bases:

>100_bases
ATTACAATTTATAATTTATTCCAAGCTTTTGATCGCAGGCCAACTAGGTCTGCGATTGGGCTTTAAAGTGCATCATAGGG
CCGATGTTGTAGATCATTGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTMQEHTADPALDFYQFDLLLTPEEREVRDRVRGFMQREVKPIINEYWEKGEFPFELIPKLAELKVCGGTIQGYGCPGLS
SVATGLVAAEMAKIDGSVCTFFGVTSGLAMSSIYYCGSEAQKEYWLPKLASMEKIGAFALTEPDNGSDASHIQTTARLEG
DHYVLNGQKRWIGNASFADVIIVWARDEATNQVTGFLVEKGTPGFEATVMHGKIAKRALWNAEIKLENCRIPASNRLEKA
RSFKDTAVVLANTRFGVAWEGVGHAQAAYEMALRYSQERKQFGKPIAGYQLIQEKLVKMLAEVVAMELTTWRLSVLRDQG
LMTDGQSSLAKMNNSAKARQIVALGREIFGGNGLLLENHIARHFADMEAVYTYEGSNEINTLVVGREITGVPAFV

Sequences:

>Translated_395_residues
MTMQEHTADPALDFYQFDLLLTPEEREVRDRVRGFMQREVKPIINEYWEKGEFPFELIPKLAELKVCGGTIQGYGCPGLS
SVATGLVAAEMAKIDGSVCTFFGVTSGLAMSSIYYCGSEAQKEYWLPKLASMEKIGAFALTEPDNGSDASHIQTTARLEG
DHYVLNGQKRWIGNASFADVIIVWARDEATNQVTGFLVEKGTPGFEATVMHGKIAKRALWNAEIKLENCRIPASNRLEKA
RSFKDTAVVLANTRFGVAWEGVGHAQAAYEMALRYSQERKQFGKPIAGYQLIQEKLVKMLAEVVAMELTTWRLSVLRDQG
LMTDGQSSLAKMNNSAKARQIVALGREIFGGNGLLLENHIARHFADMEAVYTYEGSNEINTLVVGREITGVPAFV
>Mature_394_residues
TMQEHTADPALDFYQFDLLLTPEEREVRDRVRGFMQREVKPIINEYWEKGEFPFELIPKLAELKVCGGTIQGYGCPGLSS
VATGLVAAEMAKIDGSVCTFFGVTSGLAMSSIYYCGSEAQKEYWLPKLASMEKIGAFALTEPDNGSDASHIQTTARLEGD
HYVLNGQKRWIGNASFADVIIVWARDEATNQVTGFLVEKGTPGFEATVMHGKIAKRALWNAEIKLENCRIPASNRLEKAR
SFKDTAVVLANTRFGVAWEGVGHAQAAYEMALRYSQERKQFGKPIAGYQLIQEKLVKMLAEVVAMELTTWRLSVLRDQGL
MTDGQSSLAKMNNSAKARQIVALGREIFGGNGLLLENHIARHFADMEAVYTYEGSNEINTLVVGREITGVPAFV

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=377, Percent_Identity=40.5835543766578, Blast_Score=271, Evalue=7e-73,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=40.1685393258427, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=32.8042328042328, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI4557233, Length=358, Percent_Identity=33.7988826815642, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI226958414, Length=369, Percent_Identity=31.9783197831978, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=30.8310991957105, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI21361497, Length=344, Percent_Identity=32.5581395348837, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI7656849, Length=385, Percent_Identity=30.1298701298701, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4557235, Length=318, Percent_Identity=33.9622641509434, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI76496475, Length=318, Percent_Identity=33.9622641509434, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=30.8707124010554, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=30.8707124010554, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=30.8707124010554, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI38505218, Length=400, Percent_Identity=23.75, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI211971008, Length=404, Percent_Identity=25.2475247524752, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI48976061, Length=404, Percent_Identity=25.2475247524752, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI87081958, Length=349, Percent_Identity=28.080229226361, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786223, Length=254, Percent_Identity=28.740157480315, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=386, Percent_Identity=36.0103626943005, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17508101, Length=369, Percent_Identity=30.6233062330623, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=30.0791556728232, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=29.4429708222812, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17569725, Length=384, Percent_Identity=28.6458333333333, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=392, Percent_Identity=30.8673469387755, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17533517, Length=394, Percent_Identity=28.1725888324873, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17534899, Length=387, Percent_Identity=28.6821705426357, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=284, Percent_Identity=32.0422535211268, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=27.5401069518717, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=328, Percent_Identity=32.9268292682927, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=32.8358208955224, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=31.5555555555556, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17505929, Length=358, Percent_Identity=24.8603351955307, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17551932, Length=360, Percent_Identity=23.6111111111111, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI19920834, Length=386, Percent_Identity=39.119170984456, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=32.1808510638298, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=32.7077747989276, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=32.8912466843501, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=29.1777188328912, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=29.4736842105263, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281363737, Length=388, Percent_Identity=29.3814432989691, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281365206, Length=334, Percent_Identity=25.4491017964072, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585193, Length=334, Percent_Identity=25.4491017964072, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585195, Length=334, Percent_Identity=25.4491017964072, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585191, Length=334, Percent_Identity=25.4491017964072, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43724; Mature: 43592

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMQEHTADPALDFYQFDLLLTPEEREVRDRVRGFMQREVKPIINEYWEKGEFPFELIPK
CCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LAELKVCGGTIQGYGCPGLSSVATGLVAAEMAKIDGSVCTFFGVTSGLAMSSIYYCGSEA
HHHEEECCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCHH
QKEYWLPKLASMEKIGAFALTEPDNGSDASHIQTTARLEGDHYVLNGQKRWIGNASFADV
HHHHCCHHHHHHHHHCEEEEECCCCCCCHHHHEEHEEECCCEEEECCCCEECCCCCCEEE
IIVWARDEATNQVTGFLVEKGTPGFEATVMHGKIAKRALWNAEIKLENCRIPASNRLEKA
EEEEECCCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHCCEEEEECCCCCCHHHHHHH
RSFKDTAVVLANTRFGVAWEGVGHAQAAYEMALRYSQERKQFGKPIAGYQLIQEKLVKML
HCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEVVAMELTTWRLSVLRDQGLMTDGQSSLAKMNNSAKARQIVALGREIFGGNGLLLENHI
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHH
ARHFADMEAVYTYEGSNEINTLVVGREITGVPAFV
HHHHHCCEEEEEECCCCCCEEEEEECEECCCCCCC
>Mature Secondary Structure 
TMQEHTADPALDFYQFDLLLTPEEREVRDRVRGFMQREVKPIINEYWEKGEFPFELIPK
CCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LAELKVCGGTIQGYGCPGLSSVATGLVAAEMAKIDGSVCTFFGVTSGLAMSSIYYCGSEA
HHHEEECCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCHH
QKEYWLPKLASMEKIGAFALTEPDNGSDASHIQTTARLEGDHYVLNGQKRWIGNASFADV
HHHHCCHHHHHHHHHCEEEEECCCCCCCHHHHEEHEEECCCEEEECCCCEECCCCCCEEE
IIVWARDEATNQVTGFLVEKGTPGFEATVMHGKIAKRALWNAEIKLENCRIPASNRLEKA
EEEEECCCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHCCEEEEECCCCCCHHHHHHH
RSFKDTAVVLANTRFGVAWEGVGHAQAAYEMALRYSQERKQFGKPIAGYQLIQEKLVKML
HCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEVVAMELTTWRLSVLRDQGLMTDGQSSLAKMNNSAKARQIVALGREIFGGNGLLLENHI
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHH
ARHFADMEAVYTYEGSNEINTLVVGREITGVPAFV
HHHHHCCEEEEEECCCCCCEEEEEECEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]