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The map label for this gene is argD [H]

Identifier: 159899826

GI number: 159899826

Start: 4174298

End: 4175479

Strand: Direct

Name: argD [H]

Synonym: Haur_3309

Alternate gene names: 159899826

Gene position: 4174298-4175479 (Clockwise)

Preceding gene: 159899825

Following gene: 159899827

Centisome position: 65.77

GC content: 52.45

Gene sequence:

>1182_bases
ATGACTGAACAACAAGCATTTGCAGATTTAGAAGCTGCCCATAGCGCCGGAGTTTACGCCAAGCGTCCGATTACTTTGGT
GCGTGGCAGCGGCGCAACCCTCTACGACGATCACGGCCAAGCTTATCTTGATTGTGGTTCAGGCATTGGGGTTGCCAACA
TCGGCCATTGTCACCCAACGGTGGTGCAGGCAATCGCCGAGCAGGCCGCAACCCTGACGGTTTGCCCCGAAGCCTTTCAT
AATGATCAACGGGCCTTATTGCAAGCCGAGTTGGTACAATTATTTCCAGCCGAATTTCAACGGGTCTTTTTGTGCAACAG
TGGCACGGAAGCAGTCGAAGCTGCTTTGAAATTTGCGCGCATGGCTACAGGCCGTACCGCGATTGTAGCAACCATGCGTG
GCTTTCATGGTCGCACTTTTGGAGCTTTGAGCGCTACATGGGAGAGTCACTACCGCGAGCCATTTATGCCGCTTGTGCCC
GATTTTAGCCATATTCCCTACAATAATATCGAGCGTTTGCAAAACGCTATTACTGAGCAAACTGCTGCGTTGATTGTTGA
AATTATCCAAGGCGAGGGCGGCATTCGCCCGGCAACCGCTGAATTTTTGCAAGCAGCCCAAACAATTTGCCGCGAACGCG
GAGCTTTATTGATTCTCGATGAAGTCCAAACTGGCTTTGGCCGTACTGGGCGAATGTTTGCATTTGAGCATTTTGACTTA
GAGCCAGACTTCGTTTGTTTGGCCAAGGCCTTGGGCGGGGGCATGCCAATGGGCGCGGTGGTGATCAACCAGCGAGTTGG
CGCATTGGCGACTGGCACGCATGGCTCGACCTTTGGCGGCAACCCTTTGGCGTGTGCAGCGGCGCGGGCTTCGCTGCGGG
TAATTCGTGAAGAACAATTGGTCGATCAAACTGCCGAAAAAGGCGATTGGCTGCTCGCTCAATTACGTTCAATCAACTCG
CCCAAAATTCGCGAGGTGCGCGGGTTAGGCTTGATGGTGGGCATTGAACTCAAGGAAAAAGTTGCGCCCTATCTACAAAA
ATTGATGAACCAGCATCAGATTATTGCGCTCAATTCGGGCAGCAATGTGTTGCGCTTGCTCCCGCCGTTGGTGATTAATT
GGGCTGAATTAGAACGCTTAGTGGCAACCTTACGCAGCATCTTCGAGGAGCCAAGCGCATGA

Upstream 100 bases:

>100_bases
TCATCATTGGCGATGGCCGCCGTGACCAACCAATTAGCGATGCCCTTGCTGGCCAGGGAACGATCATCGAATAAACGGCT
GAGTTGCTAGGAACCAAACC

Downstream 100 bases:

>100_bases
ACGATCAACAAGCTTTGCAGTTAATTGAGGCCATGGTGGCAACACCCAGTGTTTCGGGCGACGAGGCCGCAATCGCCCAA
TTGTTGGTTGAGCAGATGAA

Product: acetylornithine and succinylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTEQQAFADLEAAHSAGVYAKRPITLVRGSGATLYDDHGQAYLDCGSGIGVANIGHCHPTVVQAIAEQAATLTVCPEAFH
NDQRALLQAELVQLFPAEFQRVFLCNSGTEAVEAALKFARMATGRTAIVATMRGFHGRTFGALSATWESHYREPFMPLVP
DFSHIPYNNIERLQNAITEQTAALIVEIIQGEGGIRPATAEFLQAAQTICRERGALLILDEVQTGFGRTGRMFAFEHFDL
EPDFVCLAKALGGGMPMGAVVINQRVGALATGTHGSTFGGNPLACAAARASLRVIREEQLVDQTAEKGDWLLAQLRSINS
PKIREVRGLGLMVGIELKEKVAPYLQKLMNQHQIIALNSGSNVLRLLPPLVINWAELERLVATLRSIFEEPSA

Sequences:

>Translated_393_residues
MTEQQAFADLEAAHSAGVYAKRPITLVRGSGATLYDDHGQAYLDCGSGIGVANIGHCHPTVVQAIAEQAATLTVCPEAFH
NDQRALLQAELVQLFPAEFQRVFLCNSGTEAVEAALKFARMATGRTAIVATMRGFHGRTFGALSATWESHYREPFMPLVP
DFSHIPYNNIERLQNAITEQTAALIVEIIQGEGGIRPATAEFLQAAQTICRERGALLILDEVQTGFGRTGRMFAFEHFDL
EPDFVCLAKALGGGMPMGAVVINQRVGALATGTHGSTFGGNPLACAAARASLRVIREEQLVDQTAEKGDWLLAQLRSINS
PKIREVRGLGLMVGIELKEKVAPYLQKLMNQHQIIALNSGSNVLRLLPPLVINWAELERLVATLRSIFEEPSA
>Mature_392_residues
TEQQAFADLEAAHSAGVYAKRPITLVRGSGATLYDDHGQAYLDCGSGIGVANIGHCHPTVVQAIAEQAATLTVCPEAFHN
DQRALLQAELVQLFPAEFQRVFLCNSGTEAVEAALKFARMATGRTAIVATMRGFHGRTFGALSATWESHYREPFMPLVPD
FSHIPYNNIERLQNAITEQTAALIVEIIQGEGGIRPATAEFLQAAQTICRERGALLILDEVQTGFGRTGRMFAFEHFDLE
PDFVCLAKALGGGMPMGAVVINQRVGALATGTHGSTFGGNPLACAAARASLRVIREEQLVDQTAEKGDWLLAQLRSINSP
KIREVRGLGLMVGIELKEKVAPYLQKLMNQHQIIALNSGSNVLRLLPPLVINWAELERLVATLRSIFEEPSA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=381, Percent_Identity=34.9081364829396, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI24119277, Length=413, Percent_Identity=31.2348668280872, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI13994255, Length=423, Percent_Identity=30.9692671394799, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI284507298, Length=286, Percent_Identity=35.6643356643357, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=27.8450363196126, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=26.4423076923077, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=26.3157894736842, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI188536080, Length=413, Percent_Identity=24.9394673123487, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38679950, Length=413, Percent_Identity=24.9394673123487, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38679946, Length=413, Percent_Identity=24.9394673123487, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI145693181, Length=378, Percent_Identity=42.3280423280423, Blast_Score=284, Evalue=6e-78,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=39.6325459317585, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1789759, Length=373, Percent_Identity=36.4611260053619, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=34.2364532019704, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787560, Length=390, Percent_Identity=35.3846153846154, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786991, Length=407, Percent_Identity=32.6781326781327, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786349, Length=332, Percent_Identity=33.7349397590361, Blast_Score=125, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=35.0383631713555, Blast_Score=255, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI32564660, Length=415, Percent_Identity=32.289156626506, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI25144274, Length=263, Percent_Identity=36.1216730038023, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI71992977, Length=425, Percent_Identity=29.8823529411765, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71981843, Length=179, Percent_Identity=32.4022346368715, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=415, Percent_Identity=24.3373493975904, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71992985, Length=112, Percent_Identity=39.2857142857143, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=385, Percent_Identity=38.4415584415584, Blast_Score=248, Evalue=8e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=407, Percent_Identity=37.8378378378378, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6324386, Length=405, Percent_Identity=27.4074074074074, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6321456, Length=380, Percent_Identity=25.2631578947368, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=33.5051546391753, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI21356575, Length=412, Percent_Identity=33.0097087378641, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI28574759, Length=419, Percent_Identity=33.1742243436754, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161085790, Length=424, Percent_Identity=32.7830188679245, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=24.0740740740741, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=24.0740740740741, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=24.0740740740741, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42611; Mature: 42480

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQQAFADLEAAHSAGVYAKRPITLVRGSGATLYDDHGQAYLDCGSGIGVANIGHCHPT
CCCHHHHHHHHHHHHCCCEECCCEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCHH
VVQAIAEQAATLTVCPEAFHNDQRALLQAELVQLFPAEFQRVFLCNSGTEAVEAALKFAR
HHHHHHHHHCEEEECHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHH
MATGRTAIVATMRGFHGRTFGALSATWESHYREPFMPLVPDFSHIPYNNIERLQNAITEQ
HHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TAALIVEIIQGEGGIRPATAEFLQAAQTICRERGALLILDEVQTGFGRTGRMFAFEHFDL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECHHCCCCCCCCEEEEEECCC
EPDFVCLAKALGGGMPMGAVVINQRVGALATGTHGSTFGGNPLACAAARASLRVIREEQL
CCHHHHHHHHHCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VDQTAEKGDWLLAQLRSINSPKIREVRGLGLMVGIELKEKVAPYLQKLMNQHQIIALNSG
HHHHHHCCHHHHHHHHCCCCCCHHHHHCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCC
SNVLRLLPPLVINWAELERLVATLRSIFEEPSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEQQAFADLEAAHSAGVYAKRPITLVRGSGATLYDDHGQAYLDCGSGIGVANIGHCHPT
CCHHHHHHHHHHHHCCCEECCCEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCHH
VVQAIAEQAATLTVCPEAFHNDQRALLQAELVQLFPAEFQRVFLCNSGTEAVEAALKFAR
HHHHHHHHHCEEEECHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHH
MATGRTAIVATMRGFHGRTFGALSATWESHYREPFMPLVPDFSHIPYNNIERLQNAITEQ
HHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TAALIVEIIQGEGGIRPATAEFLQAAQTICRERGALLILDEVQTGFGRTGRMFAFEHFDL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECHHCCCCCCCCEEEEEECCC
EPDFVCLAKALGGGMPMGAVVINQRVGALATGTHGSTFGGNPLACAAARASLRVIREEQL
CCHHHHHHHHHCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VDQTAEKGDWLLAQLRSINSPKIREVRGLGLMVGIELKEKVAPYLQKLMNQHQIIALNSG
HHHHHHCCHHHHHHHHCCCCCCHHHHHCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCC
SNVLRLLPPLVINWAELERLVATLRSIFEEPSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11489859 [H]