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The map label for this gene is cobT

Identifier: 159899781

GI number: 159899781

Start: 4125109

End: 4126161

Strand: Direct

Name: cobT

Synonym: Haur_3263

Alternate gene names: 159899781

Gene position: 4125109-4126161 (Clockwise)

Preceding gene: 159899780

Following gene: 159899787

Centisome position: 65.0

GC content: 54.61

Gene sequence:

>1053_bases
GTGAACATTGACGATCTATCAGCCACGATTGCCGAGCTTGATTCCGCTGCAATTCAGCAAGCGCAACAACGCCAAGATCA
ACTGACCAAGCCGCAGGGAGCGCTGGGCCTGCTCGAAACCTTGTCAATTCAATTAGCAGGTATCACTCAGCAATGCCCGC
CAAGCGTGCAAAAACCGATCATTGTCGTTGCGGCAGCCGATCATGGGGTGGCTGAATATGGAGTGAGCGCCTATCCCTCA
AGCGTCACGGCCCAAATGGTGGCGAATTTTTTGGCGGGCGGCGCGGCGGTGAGCGTTTTGGCCCGCCATGTTGGAGCTGA
ACTCTTAATCATTGATGCGGGGGTACAAACCGCAATTGTTAGCGAGGCCGCTAATTTTCGCAGCGAATGGCTGGGGGCTG
GCACGCACAACTTGGCAATTGAACCAGCAATGAGCCAAGCCCAAGCTCAATCAGCATTTGAACGCGGCATACGCATCGCT
CATGAATTGGCTGATGCAGGCCACGATTTGATTGCGCTTGGCGAGATGGGGATTGGCAATACGACCGCTGCCGCCTGTTT
AACCGCGATCTATTGCCAGCAACCTGCGGCTGCCGTTACTGGCCATGGCACGGGCGTACAAGCCGAGCACTATCAACGCA
AAATCGAGGTTGTGGCTCAAGCAGTGGCACGGGTTGGCAGTAATGTGGATGGACTTCAGCCATTAATCGAGGTTGGCGGC
TTTGAAATTGGTATTTTGGCGGGCATTATTGTGGGTGCTGCTCAGCGGCGTGTGCCAATTTTAGTTGATGGTTTTATCAC
CACAGCGGCGGCTTTGGTAGCCCAAGCGCTTGCGCCAAAGGCGATTGATTATTGTATTGCAGCGCATTGTGGAGCTGAGC
CAGGCCATCGGATTGCTTTGCAACAATTGGGTTTGCGGCCATTGCTTGAGCTTGATTTACGGCTTGGCGAAGGCAGCGGC
GCGGCTTTGGCGATTCCGTTGGTGCAAGCGGCCTGTCGCATTTTAAGCGAAATGGCCACTTTTGCTAGCGCCCACGTTGA
TACGGCGCTCTAA

Upstream 100 bases:

>100_bases
CCAGCCGAATCCAAGCCTAGTCCAACTGATGTCCAACGTTTGTCCTCGAATGAAATTGATGCTATTCTGCGCGGCGATCA
ACCTATACCTGGAGCAACGA

Downstream 100 bases:

>100_bases
AAAACGAATGGCCAGCAGGTATCGCCTGCTGGCCAGCGAGTAGCTCGACAAGACTACCACGAAACCCCATCTTTTTTAGC
ATCGAAGGTTTCCAAATCAA

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MNIDDLSATIAELDSAAIQQAQQRQDQLTKPQGALGLLETLSIQLAGITQQCPPSVQKPIIVVAAADHGVAEYGVSAYPS
SVTAQMVANFLAGGAAVSVLARHVGAELLIIDAGVQTAIVSEAANFRSEWLGAGTHNLAIEPAMSQAQAQSAFERGIRIA
HELADAGHDLIALGEMGIGNTTAAACLTAIYCQQPAAAVTGHGTGVQAEHYQRKIEVVAQAVARVGSNVDGLQPLIEVGG
FEIGILAGIIVGAAQRRVPILVDGFITTAAALVAQALAPKAIDYCIAAHCGAEPGHRIALQQLGLRPLLELDLRLGEGSG
AALAIPLVQAACRILSEMATFASAHVDTAL

Sequences:

>Translated_350_residues
MNIDDLSATIAELDSAAIQQAQQRQDQLTKPQGALGLLETLSIQLAGITQQCPPSVQKPIIVVAAADHGVAEYGVSAYPS
SVTAQMVANFLAGGAAVSVLARHVGAELLIIDAGVQTAIVSEAANFRSEWLGAGTHNLAIEPAMSQAQAQSAFERGIRIA
HELADAGHDLIALGEMGIGNTTAAACLTAIYCQQPAAAVTGHGTGVQAEHYQRKIEVVAQAVARVGSNVDGLQPLIEVGG
FEIGILAGIIVGAAQRRVPILVDGFITTAAALVAQALAPKAIDYCIAAHCGAEPGHRIALQQLGLRPLLELDLRLGEGSG
AALAIPLVQAACRILSEMATFASAHVDTAL
>Mature_350_residues
MNIDDLSATIAELDSAAIQQAQQRQDQLTKPQGALGLLETLSIQLAGITQQCPPSVQKPIIVVAAADHGVAEYGVSAYPS
SVTAQMVANFLAGGAAVSVLARHVGAELLIIDAGVQTAIVSEAANFRSEWLGAGTHNLAIEPAMSQAQAQSAFERGIRIA
HELADAGHDLIALGEMGIGNTTAAACLTAIYCQQPAAAVTGHGTGVQAEHYQRKIEVVAQAVARVGSNVDGLQPLIEVGG
FEIGILAGIIVGAAQRRVPILVDGFITTAAALVAQALAPKAIDYCIAAHCGAEPGHRIALQQLGLRPLLELDLRLGEGSG
AALAIPLVQAACRILSEMATFASAHVDTAL

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=345, Percent_Identity=41.4492753623188, Blast_Score=230, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_HERA2 (A9B732)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546028.1
- ProteinModelPortal:   A9B732
- SMR:   A9B732
- GeneID:   5735131
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3263
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- BioCyc:   HAUR316274:HAUR_3263-MONOMER
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 35909; Mature: 35909

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: ACT_SITE 317-317

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDDLSATIAELDSAAIQQAQQRQDQLTKPQGALGLLETLSIQLAGITQQCPPSVQKPI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCE
IVVAAADHGVAEYGVSAYPSSVTAQMVANFLAGGAAVSVLARHVGAELLIIDAGVQTAIV
EEEEECCCCHHHCCCHHCCHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEEECCCHHHHH
SEAANFRSEWLGAGTHNLAIEPAMSQAQAQSAFERGIRIAHELADAGHDLIALGEMGIGN
HHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
TTAAACLTAIYCQQPAAAVTGHGTGVQAEHYQRKIEVVAQAVARVGSNVDGLQPLIEVGG
HHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
FEIGILAGIIVGAAQRRVPILVDGFITTAAALVAQALAPKAIDYCIAAHCGAEPGHRIAL
CHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHH
QQLGLRPLLELDLRLGEGSGAALAIPLVQAACRILSEMATFASAHVDTAL
HHHCCCHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIDDLSATIAELDSAAIQQAQQRQDQLTKPQGALGLLETLSIQLAGITQQCPPSVQKPI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCE
IVVAAADHGVAEYGVSAYPSSVTAQMVANFLAGGAAVSVLARHVGAELLIIDAGVQTAIV
EEEEECCCCHHHCCCHHCCHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEEECCCHHHHH
SEAANFRSEWLGAGTHNLAIEPAMSQAQAQSAFERGIRIAHELADAGHDLIALGEMGIGN
HHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
TTAAACLTAIYCQQPAAAVTGHGTGVQAEHYQRKIEVVAQAVARVGSNVDGLQPLIEVGG
HHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
FEIGILAGIIVGAAQRRVPILVDGFITTAAALVAQALAPKAIDYCIAAHCGAEPGHRIAL
CHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHH
QQLGLRPLLELDLRLGEGSGAALAIPLVQAACRILSEMATFASAHVDTAL
HHHCCCHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA