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The map label for this gene is pknH [H]

Identifier: 159899552

GI number: 159899552

Start: 3830159

End: 3831544

Strand: Direct

Name: pknH [H]

Synonym: Haur_3033

Alternate gene names: 159899552

Gene position: 3830159-3831544 (Clockwise)

Preceding gene: 159899551

Following gene: 159899553

Centisome position: 60.35

GC content: 49.71

Gene sequence:

>1386_bases
ATGCATCTTGTTGCAGGTCAACAATATGGGCGCTACGAAATTGTTGATGATCGTTTGGCCGAAGGGCTTTCCGGCCCGGT
CTACCATGCGATCATCAATCACGATGATGGGCATCGTGAAGAAGTTGCGCTCAAATTTCTGACGAATAAACTTCCTCAAG
TTCGTCAGTATTTTATGAATGAGGAACGTTTGCTGAAAAAAGCCGAGCACCCTCATGTGATCGGCTTTGTCCACAGTAAT
GTCCGTGACGAGCCGTATACGCTGGCCACGACGTTCGTTTATGCCTACAGCAATAAAGAGTTATCGAAGCAAAAAAGCGA
AACTATCGCGCTGCAAATCGCCGAACAAATTGGCAGTGCTTTGGATTATCTGCATATTGCCCACCCTGATAGCCCAGTTA
TTCATCGTGACGTAAAGCCCGATAACATTTTGGTCGATAAAGCCACGCACGATGCGATTCTGATTGACCTCAGTGTTGCT
TCGCACGAACGCTTTGCCTTGGTCGATGAACGTGGTTTTGGTACGCCGCCGTATATGGCTCCTGAGCAATATACGGGGCA
TGAAGTGCCAGCAACCGACCAATATGCCTTGGCCTTGGTCGTCTATTATTTCCTGACAGGCGATACAATCCCCACGATCA
AACCACCTAAAATCAAGGGGATGGAATCGAATGATCCTCAAGTATATCAAGCAGCTTTGGCGATTTGGAATACTGAATTT
CGCCAGCAACTGGCGGCTCAAAACGAGCGGATTCGCAAAAACTTGGCCAAACATCCCACGGCCATCGAGGTTTTCTTAAA
AGCGACTGCCTTTGAGCCACACGATCGTTATAGCTCATGTGCAGCCTTCAGCATGGCGATGCACGAAGCCTTACGCAATG
ATGGAGCCGCCTTTGCAGCCCCAAGCATGCCCATCAGCAACTCACGGCGCTCAACCATGATCAGTATTGGGGCCATTGGT
GCTCTGGTTTTAATTGCAGTGCTCTTTTTAGTCTTGGGTGGTGGCGATACGCCTGATGTCAATGGTAAAGCAACGCCAGA
ACAAGCAGCGATGCAACCAACCTCAACCTTACCCGAAACCCCGACTACTGGTGGTATTCCAACGGTCACAATCGAAGCGG
GTATTCCAACCTCAACCTTACCACCAATAGTTTCACCAACTACTGGAGGCCGCGAGGTAACCCTGAGTCAAGGCTACATT
TTGCGGGCACAACCTGGCGATGGTAGCGCGAATGCCCTTGGCAGTGGGCAAGCTCTCGAAGGCCAAAAGTTTCGGGTGCT
TGATGAGAACCCCAGCACCATCAGTGGTGATCGACGCAAATGGTTCAATGTACAACGTATCAACGGTGGAGAAACAGGAT
GGCTACCAGAAACAGTCTTACGCTAG

Upstream 100 bases:

>100_bases
TATTTTGGCAGCAGTCACAACCGCTTTAGCAACCGCCACCCGCCGTCGCCCAACTCGGATTGATCCAGGGGCTGGTAAGT
AGGCTATCGGAGGAGCGACT

Downstream 100 bases:

>100_bases
GCCACCAAGGAGCATTGCAATGAGTCAAGCTGCCAATCTGCCTAACCTCGTGGTCTATGGGCAAAGCGATGTTGGGCGAC
AACGGAATAATAACGAAGAT

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MHLVAGQQYGRYEIVDDRLAEGLSGPVYHAIINHDDGHREEVALKFLTNKLPQVRQYFMNEERLLKKAEHPHVIGFVHSN
VRDEPYTLATTFVYAYSNKELSKQKSETIALQIAEQIGSALDYLHIAHPDSPVIHRDVKPDNILVDKATHDAILIDLSVA
SHERFALVDERGFGTPPYMAPEQYTGHEVPATDQYALALVVYYFLTGDTIPTIKPPKIKGMESNDPQVYQAALAIWNTEF
RQQLAAQNERIRKNLAKHPTAIEVFLKATAFEPHDRYSSCAAFSMAMHEALRNDGAAFAAPSMPISNSRRSTMISIGAIG
ALVLIAVLFLVLGGGDTPDVNGKATPEQAAMQPTSTLPETPTTGGIPTVTIEAGIPTSTLPPIVSPTTGGREVTLSQGYI
LRAQPGDGSANALGSGQALEGQKFRVLDENPSTISGDRRKWFNVQRINGGETGWLPETVLR

Sequences:

>Translated_461_residues
MHLVAGQQYGRYEIVDDRLAEGLSGPVYHAIINHDDGHREEVALKFLTNKLPQVRQYFMNEERLLKKAEHPHVIGFVHSN
VRDEPYTLATTFVYAYSNKELSKQKSETIALQIAEQIGSALDYLHIAHPDSPVIHRDVKPDNILVDKATHDAILIDLSVA
SHERFALVDERGFGTPPYMAPEQYTGHEVPATDQYALALVVYYFLTGDTIPTIKPPKIKGMESNDPQVYQAALAIWNTEF
RQQLAAQNERIRKNLAKHPTAIEVFLKATAFEPHDRYSSCAAFSMAMHEALRNDGAAFAAPSMPISNSRRSTMISIGAIG
ALVLIAVLFLVLGGGDTPDVNGKATPEQAAMQPTSTLPETPTTGGIPTVTIEAGIPTSTLPPIVSPTTGGREVTLSQGYI
LRAQPGDGSANALGSGQALEGQKFRVLDENPSTISGDRRKWFNVQRINGGETGWLPETVLR
>Mature_461_residues
MHLVAGQQYGRYEIVDDRLAEGLSGPVYHAIINHDDGHREEVALKFLTNKLPQVRQYFMNEERLLKKAEHPHVIGFVHSN
VRDEPYTLATTFVYAYSNKELSKQKSETIALQIAEQIGSALDYLHIAHPDSPVIHRDVKPDNILVDKATHDAILIDLSVA
SHERFALVDERGFGTPPYMAPEQYTGHEVPATDQYALALVVYYFLTGDTIPTIKPPKIKGMESNDPQVYQAALAIWNTEF
RQQLAAQNERIRKNLAKHPTAIEVFLKATAFEPHDRYSSCAAFSMAMHEALRNDGAAFAAPSMPISNSRRSTMISIGAIG
ALVLIAVLFLVLGGGDTPDVNGKATPEQAAMQPTSTLPETPTTGGIPTVTIEAGIPTSTLPPIVSPTTGGREVTLSQGYI
LRAQPGDGSANALGSGQALEGQKFRVLDENPSTISGDRRKWFNVQRINGGETGWLPETVLR

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI34365793, Length=218, Percent_Identity=28.4403669724771, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71984730, Length=214, Percent_Identity=27.1028037383178, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984736, Length=214, Percent_Identity=27.1028037383178, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319751, Length=172, Percent_Identity=29.6511627906977, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221377805, Length=188, Percent_Identity=31.3829787234043, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221377807, Length=188, Percent_Identity=31.3829787234043, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 50467; Mature: 50467

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLVAGQQYGRYEIVDDRLAEGLSGPVYHAIINHDDGHREEVALKFLTNKLPQVRQYFMN
CCCCCCCCCCCEEEEHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHCC
EERLLKKAEHPHVIGFVHSNVRDEPYTLATTFVYAYSNKELSKQKSETIALQIAEQIGSA
HHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LDYLHIAHPDSPVIHRDVKPDNILVDKATHDAILIDLSVASHERFALVDERGFGTPPYMA
HHEEEEECCCCCCEECCCCCCCEEEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCC
PEQYTGHEVPATDQYALALVVYYFLTGDTIPTIKPPKIKGMESNDPQVYQAALAIWNTEF
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RQQLAAQNERIRKNLAKHPTAIEVFLKATAFEPHDRYSSCAAFSMAMHEALRNDGAAFAA
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEC
PSMPISNSRRSTMISIGAIGALVLIAVLFLVLGGGDTPDVNGKATPEQAAMQPTSTLPET
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCC
PTTGGIPTVTIEAGIPTSTLPPIVSPTTGGREVTLSQGYILRAQPGDGSANALGSGQALE
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCCCCCCCCCCC
GQKFRVLDENPSTISGDRRKWFNVQRINGGETGWLPETVLR
CCEEEEECCCCCCCCCCCHHEEEEEEECCCCCCCCCHHHCC
>Mature Secondary Structure
MHLVAGQQYGRYEIVDDRLAEGLSGPVYHAIINHDDGHREEVALKFLTNKLPQVRQYFMN
CCCCCCCCCCCEEEEHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHCC
EERLLKKAEHPHVIGFVHSNVRDEPYTLATTFVYAYSNKELSKQKSETIALQIAEQIGSA
HHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LDYLHIAHPDSPVIHRDVKPDNILVDKATHDAILIDLSVASHERFALVDERGFGTPPYMA
HHEEEEECCCCCCEECCCCCCCEEEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCC
PEQYTGHEVPATDQYALALVVYYFLTGDTIPTIKPPKIKGMESNDPQVYQAALAIWNTEF
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RQQLAAQNERIRKNLAKHPTAIEVFLKATAFEPHDRYSSCAAFSMAMHEALRNDGAAFAA
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEC
PSMPISNSRRSTMISIGAIGALVLIAVLFLVLGGGDTPDVNGKATPEQAAMQPTSTLPET
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCC
PTTGGIPTVTIEAGIPTSTLPPIVSPTTGGREVTLSQGYILRAQPGDGSANALGSGQALE
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCCCCCCCCCCC
GQKFRVLDENPSTISGDRRKWFNVQRINGGETGWLPETVLR
CCEEEEECCCCCCCCCCCHHEEEEEEECCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]