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The map label for this gene is bvgS [H]

Identifier: 159899382

GI number: 159899382

Start: 3633183

End: 3634451

Strand: Direct

Name: bvgS [H]

Synonym: Haur_2863

Alternate gene names: 159899382

Gene position: 3633183-3634451 (Clockwise)

Preceding gene: 159899381

Following gene: 159899383

Centisome position: 57.25

GC content: 47.28

Gene sequence:

>1269_bases
ATGCGTACTCAATACCCTACAAACGAAGCCCAACGTCTTGCTGCCCTGCAAAGTTATGGCTTGCTGGCCCGCCCCTATAT
TCACGAATTCGATGAATTAGCCCGCTTAGCGGCGCTTTTTTGTGCGACACCGATTGCGATTATTTCGTTGATCGATCATA
AATATCAATATATCAAAGCGGCTTTTGGCAGCCAACTCAAAACAATTCCGCGTAAATATTCGTGTTGTGCGCAAACGGTA
GTTGAGCGTGAGCTGGTTGTTTATGATCAAGCCAGCCTTGAGCGTAGTTTTGGGCATCATCCCTTAGTGCAGCAGGGTTT
TCAGTTCTATGCGGGCATGCCGATTATCAATCAACAAGGCTTTGCTCTCGGTTGTATCGCGGTGATCGATCACCAACCTC
GCCAACTTAGCTCACAGCAACGTGAAAGTTTACAATTGATCGCTCAGCAATTAAGCCATCAATTTGAGCTGTTTCGTCAA
GTTCAGCAATTAACGGCCTTGCCTCATGATGTTTTCCATTCGAGCATCGCCAGTGATCCCCAAGTGCCGAGCAAAACGCC
CTTAATTGCTAAAATGAGCCAGCAATTGCATAAACCGCTGCATACGATTATGACCGATAGTCAGCTTTTGGCTGATCAGT
TGATCGAAGCGGGAGTAGCCGAGTTGGAGCCAACTGCCCATCACATTCAAGAAACCAGCGCCCAGCTTTTGGCATTAATC
GACGATATGATCGATTTGGCCAAGATTGAACATGGCCAACTTGATGTGCATTATGAAGAGGTTTGTCTGGGGCCGTTGAT
CGATCAATTAAATGTGATTGTTGCGCCATTGATGGTGCGCAATCATAATACGTTTCATGTGCAAATTGGCACACGCCAAC
GCATTTTTTGGAGTGATAATCGCTTGGTACGTCAAATTTTGGTAAATGTGGTTGGTAATGCTGCCAAATTTACCCACGCT
GGCTCAGTGCGCATCGAAGTCAGCGAAGAACAGCGCAACGGTCAGCATTATTTGGCCTTTCATGTGATCGATACAGGCAT
TGGCATGACTCCTGAGCAACAAGTCCAATTGTTTCAAGAGCAACCGCGTTTGGGAAAAAGCCTGGGCAGCCAACCAAGCA
CTGGTTTGGGTTTGGCGATTAGCAAACGCTTGGCTTTATTGCTTGGCGGCGATATTACCTTGAGCAGCAATCCTGGGATC
GGCAGTCATTTCACGCTTTACCTACCCTTGAAAGCAACCCCGCAAATTACACAGCCGCAGGCCGCTTAA

Upstream 100 bases:

>100_bases
CGAAGTCACCCAAACAGCCCCCTCGACAGTGGCTTAACGCTATGTCAAGATCGTACTAGCCTTTAGTTTCCAGCGATCTT
AATTTTAGCGAGGAGCCGCC

Downstream 100 bases:

>100_bases
TGCTAAACTTGATTGGCAATAAATTTTAGTATTCTTGAGGATTCACCACCCTTCCGTCCCGCCTCAAGGCGGGAAACGCC
GGGGGCTTTAATCCCCCGGC

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MRTQYPTNEAQRLAALQSYGLLARPYIHEFDELARLAALFCATPIAIISLIDHKYQYIKAAFGSQLKTIPRKYSCCAQTV
VERELVVYDQASLERSFGHHPLVQQGFQFYAGMPIINQQGFALGCIAVIDHQPRQLSSQQRESLQLIAQQLSHQFELFRQ
VQQLTALPHDVFHSSIASDPQVPSKTPLIAKMSQQLHKPLHTIMTDSQLLADQLIEAGVAELEPTAHHIQETSAQLLALI
DDMIDLAKIEHGQLDVHYEEVCLGPLIDQLNVIVAPLMVRNHNTFHVQIGTRQRIFWSDNRLVRQILVNVVGNAAKFTHA
GSVRIEVSEEQRNGQHYLAFHVIDTGIGMTPEQQVQLFQEQPRLGKSLGSQPSTGLGLAISKRLALLLGGDITLSSNPGI
GSHFTLYLPLKATPQITQPQAA

Sequences:

>Translated_422_residues
MRTQYPTNEAQRLAALQSYGLLARPYIHEFDELARLAALFCATPIAIISLIDHKYQYIKAAFGSQLKTIPRKYSCCAQTV
VERELVVYDQASLERSFGHHPLVQQGFQFYAGMPIINQQGFALGCIAVIDHQPRQLSSQQRESLQLIAQQLSHQFELFRQ
VQQLTALPHDVFHSSIASDPQVPSKTPLIAKMSQQLHKPLHTIMTDSQLLADQLIEAGVAELEPTAHHIQETSAQLLALI
DDMIDLAKIEHGQLDVHYEEVCLGPLIDQLNVIVAPLMVRNHNTFHVQIGTRQRIFWSDNRLVRQILVNVVGNAAKFTHA
GSVRIEVSEEQRNGQHYLAFHVIDTGIGMTPEQQVQLFQEQPRLGKSLGSQPSTGLGLAISKRLALLLGGDITLSSNPGI
GSHFTLYLPLKATPQITQPQAA
>Mature_422_residues
MRTQYPTNEAQRLAALQSYGLLARPYIHEFDELARLAALFCATPIAIISLIDHKYQYIKAAFGSQLKTIPRKYSCCAQTV
VERELVVYDQASLERSFGHHPLVQQGFQFYAGMPIINQQGFALGCIAVIDHQPRQLSSQQRESLQLIAQQLSHQFELFRQ
VQQLTALPHDVFHSSIASDPQVPSKTPLIAKMSQQLHKPLHTIMTDSQLLADQLIEAGVAELEPTAHHIQETSAQLLALI
DDMIDLAKIEHGQLDVHYEEVCLGPLIDQLNVIVAPLMVRNHNTFHVQIGTRQRIFWSDNRLVRQILVNVVGNAAKFTHA
GSVRIEVSEEQRNGQHYLAFHVIDTGIGMTPEQQVQLFQEQPRLGKSLGSQPSTGLGLAISKRLALLLGGDITLSSNPGI
GSHFTLYLPLKATPQITQPQAA

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=31.4410480349345, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=31.2757201646091, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=31.4410480349345, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=30.1724137931034, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=29.6, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=24.7899159663866, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46991; Mature: 46991

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTQYPTNEAQRLAALQSYGLLARPYIHEFDELARLAALFCATPIAIISLIDHKYQYIKA
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGSQLKTIPRKYSCCAQTVVERELVVYDQASLERSFGHHPLVQQGFQFYAGMPIINQQG
HHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHCCCCHHHHHHHHHHCCCCEECCCC
FALGCIAVIDHQPRQLSSQQRESLQLIAQQLSHQFELFRQVQQLTALPHDVFHSSIASDP
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
QVPSKTPLIAKMSQQLHKPLHTIMTDSQLLADQLIEAGVAELEPTAHHIQETSAQLLALI
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHH
DDMIDLAKIEHGQLDVHYEEVCLGPLIDQLNVIVAPLMVRNHNTFHVQIGTRQRIFWSDN
HHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCEEEEECCH
RLVRQILVNVVGNAAKFTHAGSVRIEVSEEQRNGQHYLAFHVIDTGIGMTPEQQVQLFQE
HHHHHHHHHHHCCCHHEEECCEEEEEECHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHH
QPRLGKSLGSQPSTGLGLAISKRLALLLGGDITLSSNPGIGSHFTLYLPLKATPQITQPQ
CCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEECCCCCCCCCC
AA
CC
>Mature Secondary Structure
MRTQYPTNEAQRLAALQSYGLLARPYIHEFDELARLAALFCATPIAIISLIDHKYQYIKA
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGSQLKTIPRKYSCCAQTVVERELVVYDQASLERSFGHHPLVQQGFQFYAGMPIINQQG
HHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHCCCCHHHHHHHHHHCCCCEECCCC
FALGCIAVIDHQPRQLSSQQRESLQLIAQQLSHQFELFRQVQQLTALPHDVFHSSIASDP
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
QVPSKTPLIAKMSQQLHKPLHTIMTDSQLLADQLIEAGVAELEPTAHHIQETSAQLLALI
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHH
DDMIDLAKIEHGQLDVHYEEVCLGPLIDQLNVIVAPLMVRNHNTFHVQIGTRQRIFWSDN
HHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCEEEEECCH
RLVRQILVNVVGNAAKFTHAGSVRIEVSEEQRNGQHYLAFHVIDTGIGMTPEQQVQLFQE
HHHHHHHHHHHCCCHHEEECCEEEEEECHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHH
QPRLGKSLGSQPSTGLGLAISKRLALLLGGDITLSSNPGIGSHFTLYLPLKATPQITQPQ
CCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEECCCCCCCCCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]